Immuno-oncology Insights’ Post

Same-section spatial multiomics: a platform for detailed analysis of the solid tumor TME While #spatialbiology can help to better understand the #TME, current technologies are unable to simultaneously capture protein and #RNA information within the same #histological section. This month, Miltenyi Biotec’s Emily Neil (Manager, Molecular Technologies) and Ariadna Pascual (Global Product Manager) will explore technologies that allow for same-section #spatialmultiomics and simultaneous protein and #RNAdetection. Attend this webinar to: • Understand a same-section spatial multiomics assay and its advantages for protein and RNA analysis • Discover the applications of same-section spatial RNA and protein detection within I-O • Learn about automated spatial gene expression assay analysis specifically within the solid tumor TME Register for this #webinar below:

Want to learn more about how you can perform same section spatial multiomics on the #MACSima? Sign up for our webinar presented by two of the brilliant minds that helped develop this application Emily Neil, PhD and Dr. Ariadna Pascual Velázquez!

Accelerate #CGTdevelopment with rapid, cell-free, NGS-verified synthesis of long, complex #syntheticDNA Later this month, ELEGEN's Marion Meunier (Applications Scientist) and Ben Allred (Staff Scientist) will explore cell-free #DNAmanufacturing products that enable researchers to access high-accuracy long DNA with industry-leading sequence complexity. As a webinar attendee, you will: • Gain an understanding of the complex DNA sequences commonly used in the development of cell and #genetherapy • Explore how long, complex synthetic DNA constructs enable precise customization of genetic material • Learn about the advantages of rapid, cell-free synthesis of long, complex synthetic DNA constructs for the development of cell and gene therapy Register for this #webinar below:

Don't miss our upcoming webinar that explores how 3D cellular models can be generated and utilized to understand physiological pathways and minimize the use of animals for drug development. Learn about the creation, validation, and application of 3D models for diseases like cancer and autoimmunity in this exciting event. #3DModels #DrugDevelopment https://lnkd.in/ggSFrwKk

Register today for this Webinar to gain insights on the impact of process intensification on virus-based manufacturing to meet demands of Cell and Gene Therapy demands. Register Today! #viralvector #processintensification #upstream #celltherapy #genetherapy #tfdf

Commercial-scale manufacture of #lentivirus for ex vivo and #invivotherapies This month, Rachel Legmann (Senior Director of Technology, Gene Therapy, Repligen Corporation) and Michelle Yen Tran (Process Development Scientist, McGill University) discuss a tangential flow depth filtration system that is adapted to the fragility of envelope viruses and can be scaled to industrial-size production #bioreactors. Attend this webinar to learn about: • A #tangentialflow depth #filtrationsystem that is adapted to the fragility of #envelopeviruses and can be scaled to industrial-size production #bioreactors. • How to reduce loss of envelope virus functionality • Targeting affordable #viralvectormanufacturing by reducing cost per dose Register for this #webinar below:

Enhancing CAR-T cell generation: optimizing non-viral engineering of resting T cells for improved #cancerimmunotherapy This May, Akshaya Chandrasekaran (R&D Scientist, Thermo Fisher Scientific) will explore a system to optimize the generation of CAR-T cells from resting T cells as part of a clinically relevant CAR-T cell therapy manufacturing workflow, ensuring their safety, scalability, and efficacy Attend this webinar to learn about: • Ensuring the safety, scalability, and efficacy of resting T cells in cancer immunotherapy • How non-viral gene delivery using the CTS™ Xenon™ #ElectroporationSystem in combination • with CTS™ Xenon™ Lower Conductivity Electroporation Buffer can optimize the generation of CAR-T cells from resting T cells • Achieving effective membrane penetration in difficult-to-transfect cell types Register for this upcoming #webinar below:

Enhancing CAR-T cell generation: optimizing non-viral engineering of resting T cells for improved #cancerimmunotherapy While resting #Tcells are a desirable starting material for producing genetically modified #CARTcells, it is challenging to perform non-viral cell engineering of them. This May, Akshaya Chandrasekaran (R&D Scientist, Thermo Fisher Scientific) will explore a system to optimize the generation of CAR-T cells from resting T cells as part of a clinically relevant CAR-T cell therapy manufacturing workflow, ensuring their safety, scalability, and efficacy Register for this upcoming #webinar below:

Transform your research with next-generation sequencing (NGS) technologies 🧬 Join our new webinar series where experts from Psomagen, Decode Health, and Agilent Technologies discuss how quality control in PacBio HiFi long-read sequencing and RNA sequencing aids in discovering new biomarker candidates for diagnostic and therapeutic applications. #NGS #nextgenerationsequencing #qualitycontrol #biomarkers #diagnostics

Transform your research with next-generation sequencing (NGS) technologies 🧬 Join our new webinar series where experts from Psomagen, Decode Health, and Agilent Technologies discuss how quality control in PacBio HiFi long-read sequencing and RNA sequencing aids in discovering new biomarker candidates for diagnostic and therapeutic applications. #NGS #nextgenerationsequencing #qualitycontrol #biomarkers #diagnostics