Initial Therapeutics’ Post

Gordian Biotechnology is all about predicting patient outcomes, and are now hiring a Head of Translational Genomics to envision and enact strategy to identify patient segments most likely to match responses we're seeing preclinically. You'll have access to unprecedented in vivo datasets showing therapeutic potential from experimental tests in half a dozen species, as well as patient samples. From this and additional data you seek out, you'll explore and decide the best ways for us to identify patients likely to respond in clinical trials, e.g. endotypes sharing pathophysiology with preclinical models, biomarkers for responsiveness, and more. You would report directly to the CSO, and be supported by an outstanding team of disease experts and wet+computational biologists. Read more and apply: https://lnkd.in/gwFgvT3T #Hiring #Biotechjobs #Startupjobs #Bayareajobs #DrugDevelopment #HumanGenetics #ComparativeGenomics #SingleCell #Genomics #MASH #Fibrosis #HeartFailure #Osteoarthritis #CreatingTime

𝐒𝐩𝐚𝐭𝐢𝐚𝐥 𝐆𝐞𝐧𝐨𝐦𝐢𝐜𝐬 𝐌𝐚𝐫𝐤𝐞𝐭 𝐆𝐫𝐨𝐰𝐭𝐡 𝐃𝐫𝐢𝐯𝐞𝐫𝐬 & 𝐎𝐩𝐩𝐨𝐫𝐭𝐮𝐧𝐢𝐭𝐢𝐞𝐬 The Spatial Genomics Market is experiencing significant growth due to the rising demand for high-resolution insights into tissue biology and disease mechanisms. The push for precision medicine, particularly in oncology and neurology, is driving the adoption of spatial genomics technologies. These techniques allow researchers to analyze gene expression within the spatial context of tissues, leading to breakthroughs in understanding complex diseases. Opportunities in the spatial genomics market are expanding as pharmaceutical companies, research institutions, and healthcare providers increasingly adopt these technologies for drug discovery and diagnostics. The potential for spatial genomics to uncover new biomarkers and therapeutic targets offers promising avenues for innovation, particularly in cancer and autoimmune diseases. 𝗗𝗼𝘄𝗻𝗹𝗼𝗮𝗱 𝗮 𝗙𝗿𝗲𝗲 𝗦𝗮𝗺𝗽𝗹𝗲 𝗥𝗲𝗽𝗼𝗿𝘁:- https://lnkd.in/dpV_6dNp 𝗧𝗼𝗽 𝗞𝗲𝘆 𝗣𝗹𝗮𝘆𝗲𝗿𝘀:- Thermo Fisher Scientific | 10x Genomics | NanoString Technologies, Inc. | Illumina | Bio-Rad Laboratories | QIAGEN | Agilent Technologies | S2 Genomics | Seven Bridges #SpatialGenomics #GenomicsResearch #PrecisionMedicine #TissueBiology #CellularAnalysis #DiseaseResearch #Bioinformatics #DrugDiscovery #BiotechInnovation #HealthcareTech #GenomicsMarket #SpatialBiology

very good opportunity to build career in CNS discovery

As a dedicated Laboratory Specialist and PhD Candidate in Biochemistry, I’m passionate about leveraging cutting-edge research to make an impact in clinical testing, data analysis, and scientific research. Currently, my work focuses on investigating novel gene signatures that contribute to immune evasion in invasive breast cancer, which could lead to more targeted therapies and improved patient outcomes. With over 2 years of experience in molecular biology, I have a solid foundation in laboratory operations, including quality control, equipment maintenance, and test result analysis. Additionally, my skills in customer service and clinical research allow me to bridge the gap between technical data and patient care. I’m always eager to collaborate and share knowledge with professionals in the fields of clinical research, molecular biology, and biochemistry. Let’s connect and explore how we can drive the future of healthcare together! #Biochemistry #ClinicalResearch #LaboratorySpecialist #DataAnalysis #BreastCancerResearch #PhDCandidate #ScientificResearch

Unveiling the Cellular Symphony: Exploring Trends and Innovations in the Single Cell RNA Sequencing Technology Market Read More: https://lnkd.in/dpFQ4Fi9 This report provides a detailed and insightful analysis of the current state and future prospects of this dynamic and rapidly evolving sector. As the demand for high-resolution cellular analysis grows, the report explores the market landscape, offering a comprehensive overview of key trends, technological advancements, and market drivers. ✔ Key Highlights 🔸 Market Dynamics In-depth analysis of the factors influencing market growth, encompassing market drivers, challenges, opportunities, and trends that are shaping the trajectory of the Single Cell RNA Sequencing Technology Market. 🔸 Application Insights A detailed breakdown of the diverse applications of single-cell RNA sequencing, ranging from basic research to clinical applications, highlighting key use cases across various scientific domains. 🔸 Competitive Landscape Comprehensive profiles of major market players, their product portfolios, recent developments, and strategic initiatives. An assessment of market competitiveness and the positioning of key players in the global landscape. ✔ Market Segmentations #Company Illumina PerkinElmer 10x Genomics Thermo Fisher Scientific Oxford Nanopore Technologies QIAGEN LC Sciences Scipio bioscience Singleron Biotechnologies #Type • C1 • Chromium • Others #Application • Cancer • Microbiology • Neurobiology • Immunology • Others 💠 Stringent Datalytics #informationtechnology #itservices #marketresearch #AdvancedMaterials #IndustryInsights #MarketAnalysis #Innovation #TechTrends #Manufacturing #Engineering #FutureTech

My commentary in Genetic Engineering & Biotechnology News was just published. I am looking to promote a discussion about the NGS market. Please share your thoughts. As the marketplace is rapidly evolving, the competitive picture could change. Please share your thoughts about whether I am right or wrong. --- Hi - I'm Jeffrey Rosenfeld, PhD MBA with 15+ years of experience in genomics, biotech, biomarkers and bioinformatics. Let's chat about how I can help you with you biomarker clinical trial or performing due diligence on your next investment

A new year has just begun and we are excited to welcome new doctoral students to our team, bringing fresh perspectives, strong motivation, and enthusiasm. Eleonora Pinto, a medical biotechnologist who has been with us for three years, is now embarking on a new professional journey to further her growth as a scientist, and we are thrilled to support her in realizing her career aspirations. Eleonora will work on the development of an innovative method for generating CAR-T cells in vivo. CAR-T cell therapy typically involves extracting the patient's T lymphocytes, engineering them in the lab with a chimeric receptor (CAR) that targets tumor cells, and then reintroducing the enhanced cells into the patient. However, this process is intricate, expensive, and can lead to systemic toxicities. Moreover, there is a risk of tumor cells developing resistance to CAR. Eleonora's approach aims to generate CAR-T cells directly in the body, transferring the CAR gene to T cells in a living model. This not only can reduce time and costs but also mitigate the risk of systemic toxicities and potential alterations in cell phenotype during lab manipulations. We wish Eleonora the best of luck in her new project with us! #biotech #biotechnology #research #phd #students #career

Hi LinkedIn Fam, I am excited to share that I have successfully defended my dissertation titled "Endocytosis, Cytotoxicity, Cell death mechanism and Bioimaging of Doxorubicin-Based Combination Nanomedicines”, a subset of final dissertation titled “Ionic Nanomedicines and Biocompatible Hydrogel: Synthesis, Characterization and Application in Cancer and Drug Delivery” This achievement stands as a testament to resilience, perseverance, hard work, and commitment. I am also thankful to my advisor Dr. Noureen Siraj and committee members- Dr. Robert J Griffin, Dr. Nawab Ali, Dr. Anindya Ghosh and Dr. Brain Walker for their time and significant contribution during this phase. I am using this opportunity to share that I am actively seeking opportunities in analytical scientist roles, postdoctoral positions, or scientist position focused on cancer research. About me: PhD in Applied Chemistry, research focus on drugs design/development, characterization, in vitro and in vivo/preclinical drug testing for cancer research. Skills: Expertise in different analytical methods including chromatographic and spectroscopic methods for drug separation and characterization. Examples include UV-Vis, Fluorimetry, FTIR, NMR, DLS, GC-MS, HPLC-MS. Experience with different fluorophores, NIR dyes, photosensitizers, photothermal agents, and FRET-based bioimaging probes. Experience with cell culture/ cell-based assay (in vitro) including proliferation, cytotoxicity, flow cytometry, confocal imaging. Experience in handling and conducting experiments in animal model, tissue imaging and drug validation. Authored and co-authored various peer-reviewed publications. As I embark on my career, I eagerly anticipate the opportunity to expand my skill set, pursue my research interests, contribute to the advancement in translational cancer research, disease diagnostic, analytical chemistry and drug delivery applications. If you are hiring or know of relevant opportunities, I would love to connect! Thank you! #cancerresearch #postdoc #nanomaterials #STM #phototherapy #photothermaltherapy #photodynamictherapy #opentowork #thermaloncology #hyperthermia

Delta4 is offering a Computational Biology PhD position! Join the 3-year European Doctoral Network (DN) program, "PROMOTE," focusing on computational drug screening and synthetic lethality drug repurposing to identify novel therapeutic options for prostate cancer (PCa). PCa is the second most common malignancy, affecting ~1.3 million men every year worldwide. Tragically, there is a treatment paradox, as ~45% of PCa patients experience slow-growing cancer and are unlikely to progress rapidly, while PCa is not curable at an advanced stage. Clinical management of PCa is not optimal, as patients who do not require treatment are over-treated, while for those where immediate actions are required, efficient treatment is still needed. To fill the above gaps, PROMOTE was formed to educate doctoral candidates in emerging -omics and AI technologies. Collaborate with 13 top research centers and help discover novel non-invasive tools and more efficient therapeutic options for this disease. Apply now to be part of our cutting-edge team in Vienna, Austria. Visit our website for more details: https://delta4.ai/careers/ #Delta4AI #JoinOurTeam #PhDPosition #ComputationalBiology #DrugRepurposing #ProstateCancer #ResearchOpportunity

#SpatialGenomics: A Comprehensive Guide to Understanding #Cellular Organization ➤ 𝐂𝐥𝐢𝐜𝐤 𝐡𝐞𝐫𝐞 𝐭𝐨 𝐆𝐞𝐭 𝐏𝐃𝐅: https://lnkd.in/dt8WUsjQ #Spatialgenomics aims to assess the genomic information of individual cells within their native tissue #environment. Understanding the association between #cells and their specific locations within tissue is crucial for comprehending normal development and disease pathology. A cutting-edge technique within spatial genomics is #spatialtranscriptomics, a #molecular profiling method enabling researchers to quantify gene activity across a tissue sample and pinpoint where this activity is taking place. Spatial #genomics applications extend beyond the #cellular or tissue level, allowing for the analysis of subcellular transcriptional dynamics. #Pharmaceutical and #biotechnology companies are focusing on research and development, with R&D expenditures increasing globally. For instance, according to the International Federation of #PharmaceuticalManufacturers & Associations (IFPMA), global pharmaceutical R&D expenditure is expected to increase to USD 213 billion in 2026 from USD 189 billion in 2022. Spatial genomics has become increasingly important in ensuring precision and accuracy in #drugresearch & #development and reducing the time required for #research. ➤ 𝗗𝗿𝗶𝘃𝗲𝗿𝘀 1.   Increasing Applications of Spatial Genomics in #DrugDiscovery & Development Driving Market Growth 2.   Lack of Standardization and Concerns Over the Privacy of Genomic Data Limiting the Adoption of Spatial #GenomicsProducts 3.   Rising Adoption of Personalized #Medicines Generating Growth Opportunities for Market Players 4.   Complexities in Data Analysis to Remain a Major Challenge Impacting Market #Growth ➤ 𝑲𝒆𝒚 𝑷𝒍𝒂𝒚𝒆𝒓𝒔:  NanoString Technologies, Inc. (U.S.), 10X Genomics, Inc. (U.S.), Illumina, Inc. (U.S.), Oxford Nanopore Technologies Plc. (U.K.), Akoya Biosciences, Inc. (U.S.), Revvity, Inc. (U.S.) #SpatialBiology #SpatialTranscriptomics #SingleCellGenomics #GenomicResearch #SpatialAnalysis #MolecularBiology #LifeSciences #Bioinformatics #SpatialData #GeneExpression #TissueGenomics #SpatialMapping #GenomicTechnologies #NextGenSequencing #PrecisionMedicine #CellularBiology #SpatialOrganization #3DGenomics