International Neuromodulation Society’s Post

Fantastic real-world impact by Neuromodulation Program Members Garston Liang, Alex Thorpe, Ami Eidels & team who have partnered with the International Neuromodulation Society to produce a series of articles explaining biostatistics, now featured on The Neuromodulation Podcast Hunter Medical Research Institute (HMRI) University of Newcastle #Biostatistics #statistics #introtostatistics #stats #neuromodulation #INS

Solution Manual for Biostatistics for the Biological and Health Sciences 3rd Edition by Marc M. Triola, Mario F. Triola & Jason Roy - Complete, Elaborated and Latest Solution Manual. All Chapters

Solution Manual for Biostatistics for the Biological and Health Sciences 3rd Edition by Marc M. Triola, Mario F. Triola & Jason Roy - Complete, Elaborated and Latest Solution Manual. All Chapters

Tackling the Problem of Inconsistency in Odds Ratio Analysis I recently read an enlightening article by Michael P. Fay titled "Confidence intervals that match Fisher's exact or Blaker's exact tests," published in Biostatistics. This article delves into the inconsistencies that can arise when analyzing 2×2 tables using two-sided Fisher's exact test and the usual exact confidence intervals (CIs) for the odds ratio. 📌 Key Insights: - Test-CI Inconsistency: The article highlights how the usual exact CI might conflict with Fisher's exact test results, causing potential misinterpretations. - Matching Confidence Intervals: Fay explores solutions such as the "matching" interval, defined as the smallest interval containing the confidence set, addressing these inconsistencies. - Practical Application: The article also introduces the R package exact2×2, which automates the assignment of appropriate matching intervals for Fisher's and Blaker's exact tests. Understanding these methodologies is crucial for researchers and statisticians aiming for more accurate and consistent results in their analyses. For a detailed exploration of these concepts, you can read the full article here https://lnkd.in/g4eZfAYn. Feel free to share your thoughts or experiences with exact tests and confidence intervals in the comments below! #Biostatistics #DataAnalysis #ExactTests #ConfidenceIntervals #Research

Biostatistics: Standard deviation A standard deviation \(or \) is a measure of how dispersed the data is in relation to the mean. Low, or small, standard deviation indicates data are clustered tightly around the mean, and high, or large, standard deviation indicates data are more spread out. Problem: In a random survey of 3,015 boys age 11, the average height was 146 cm, and the standard deviation \(SD\) was 8 cm. A histogram suggested the heights were approximately normally distributed. Fill in the blanks. A\) One boy was 170 cm tall. He was above average by __________ SDs. B\) Another boy was 148 cm tall. He was above average by __________ SDs. C\) A third boy was 1.5 SDs below the average height. He was __________ cm tall. D\) If a boy was within 2.25 SDs of average height, the shortest he could have been is __________ cm and the tallest is __________ cm. Youtube video: https://lnkd.in/dR2ZMmRY \#nikolays_genetics_lessons

I invite you to read this interesting open access article on #statistic #medicine Find useful information on the #evaluation topic and #statistics https://lnkd.in/eFz6EnKP

A few quick reactions to some of the data at ESC: 1)Frail-AF study: surprising and counterintuitive results. Of note: the authors/discussants do not offer any convincing explanations and they just emphasise these are data 'as they are in real life' Over the last few years it has been my practice to gently and not repetitively (like in 'suggestion') 'nudge' non-valvular AF pts (frail or not but even more so if frail!) and their GPs to migrate from VKA to a DOAC and I was not the only one to do so. Is this study enough to change practice? Not sure. 2)NOAH-AFNET study: last ESC AF guidelines already stated that device-detected AHR episodes lasting <24 hrs should not prompt anticoagulation. This study only strengthens this recommendation. My question however is: why not extend this to < 24 hrs clinical PAF episodes? Either not all AHR episodes are real AF or indeed short PAF episodes do not justify OAC. The study authors did not have a clear answer. 3)STEP-HFpEF study. The NT-proBNP levels decreased in parallel with weight loss. Since obesity spuriously lowers NT-proBNP levels this finding suggest that Semaglutide really works by some other mechanisms beyond the 'mechanical' effect of just losing weight. And one question for my echo colleagues: any experience with transitioning to an ABCDE protocol for stress echo?

#Frequentist versus #Bayesian Approaches to Clinical Trials: A Targeted Systematic Review. Our latest blog by Giles Partington, Senior Statistician II, delves into the challenges of clinical trials for rare diseases and small populations, comparing approaches under frequentist and Bayesian frameworks and how each handle themselves. Click here to continue reading: https://lnkd.in/eafm4nPK #ClinicalTrials #RareDiseases #Phastar #blog

See how Tiffany Amariuta-Bartell at the Halıcıoğlu Data Science Institute, UC San Diego is utilizing Expanse at the San Diego Supercomputer Center (SDSC) at UC San Diego to develop statistical models to unlock genetic secrets to help improve disease diagnosis, risk assessment, and personalized medicine for underrepresented groups. #GeneticResearch #SDSC #DataScience #UCSanDiego #Expanse #DiseaseDiagnosis #PersonalizedMedicine #StatisticalModels

Mastering biostatistics is key to USMLE success! Challenge yourself with our question of the day and pave the way to exam excellence. 🏆📊 For answer explanation watch here: https://lnkd.in/gjUj5dCD #USMLEPrep #questionoftheday #USMLE #usmlestep1 #nextsteps #nextstepsusmle