International Neuromodulation Society’s Post

A REVIEW PUBLISED IN THE SCIENTIFIC JOURNAL LIFE OF MDPI ON JANUARY 2023 PROVES THAT RTMS IS A POTENTIALLY EFFECTIVE AND SAFE TREATMENT FOR CHRONIC NEUROPATHIC PAIN. CURRENT EVIDENCE SUPPORTS THE USE OF 10 HZ HF-RTMS OF THE PRIMARY MOTOR CORTEX TO REDUCE NEUROPATHIC PAIN, ESPECIALLY IN PATIENTS WITH SCI, DIABETIC NEUROPATHY AND POST-HERPETIC NEURALGIA. RTMS IS HYPOTHESIZED TO ACHIEVE ANALGESIC EFFECTS BY UPREGULATING THE PAIN THRESHOLD, INHIBITING PAIN IMPULSE, MODULATING THE BRAIN CORTEX, ALTERING IMBALANCED FUNCTIONAL CONNECTIVITY, REGULATING NEUROTROPHIN AND INCREASING ENDOGENOUS OPIOIDS AND ANTI-INFLAMMATORY CYTOKINES. https://lnkd.in/dfetaAzd

Following removal of the subdural hematoma (shown above), if significant brain tension is present in areas of large contusions and necrosis, these areas may be aspirated at the risk of additional bleeding. Learn more here | https://zurl.co/MH16.

Following removal of the subdural hematoma (shown above), if significant brain tension is present in areas of large contusions and necrosis, these areas may be aspirated at the risk of additional bleeding. Learn more here | https://zurl.co/MH16.

Opioid induced hyperalgesia Hyperalgesia may involve a reduction in nociceptive firing threshold, and an increase in the supra-threshold response. The end result is amplified nociception and an increase in pain intensity. Primary Hyperalgesia: Hyperalgesia that occurs at the site of injury and is often a reflection of peripheral sensitisation. Primary Hyperalgesia: Hyperalgesia that occurs at the site of injury and is often a reflection of peripheral sensitisation. It occurs as a result of reduced activation threshold and increased responsiveness of nociceptors (A-delta and C-fibres). Secondary Hyperalgesia: Hyperalgesia in an area adjacent to or remote from the site of injury.It is maintained by changes in the central processing of sensory information, including sensitisation of the spinal nociceptive neurons and altered descending inhibition. Secondary hyperalgesia reflects that central sensitisation (at spinal cord/brain level) is at play. It involves sensitisation of second-order neurons in the dorsal horn, as well as activation of nociceptive neurons in the brainstem and thalamus.

#FlashbackFriday 2023: Long term follow-up study indicates that SCS remains an effective to reduce pain intensity in patients with PDPN https://lnkd.in/g97sEEUr How to Cite 👉 Zuidema X, van Daal E, van Geel I, de Geus TJ, van Kuijk SMJ, de Galan BE, de Meij N, Van Zundert J. Long-Term Evaluation of Spinal Cord Stimulation in Patients With Painful Diabetic Polyneuropathy: An Eight-to-Ten-Year Prospective Cohort Study. Neuromodulation. 2023 Jul;26(5):1074-1080. doi: 10.1016/j.neurom.2022.12.003. Epub 2022 Dec 31. PMID: 3658999.

#EINS2023 Pain relief with spinal cord stimulation (SCS) starts with neural activation.      Take part this Saturday, 2 Sept 16:55-17:05 in Hall B for an oral presentation on Evoked Compound Action Potential-Controlled Closed-loop Spinal Cord Stimulation Produces Analgesia In Rats with Neuropathic Pain  presented by: Ilona Obara, MD    Come by our booth 09B to learn about the Evoke® System, an ECAP Controlled, Closed-loop spinal cord stimulation (SCS) system for the treatment of chronic pain. The Evoke System provides an objective and physiologic measure of the spinal cord’s response to stimulation and can automatically adjust on every pulse to provide consistent neural activation.      THIS CHANGES EVERYTHING.     #NoComparison #DurablePainRelief #seethepain #closedloop   #EVOKEStudy #Evoke #ECAPs  #SmartLoop  #ECAPs  #SmartSCS #ChronicPain #PAIN2023     https://lnkd.in/dtrSMTUt    Risks and Important Safety Info https://lnkd.in/d2XZ_Asn       Rx Only     The Saluda Medical Evoke® SCS System is indicated as an aid in the management of chronic intractable pain of the trunk and/or limbs.    

Pulsed electromagnetic field (PEMF) therapy shows promise in reducing pain and improving quality of life for osteoarthritis patients. https://lnkd.in/e87HuP_D

As we age our brain naturally becomes more insulin resistant. This creates a breakdown in communication between neurons, causing symptoms like changes in mood, cognitive decline, and eventually neurodegeneration. This research highlights potential ketone-based therapies for neurodegenerative diseases. Acute insulin resistance in the brain impairs synaptic activity, axonal conduction, and network synchronization. Administering ketones like D-βHb can restore these critical neuronal functions. This research suggests new therapeutic avenues for conditions involving insulin resistance, such as diabetes and Alzheimer’s disease. https://lnkd.in/g2Vr_94d

🔴 Radiation Therapy for Tendonitis 🔴 📣 Low dose radiation therapy (LDRT) has recently gained significant attention for its effectiveness in treating osteoarthritis, but its potential extends far beyond this single condition. In fact, LDRT has shown promising results in managing pain for a variety of musculoskeletal disorders, supported by a growing body of evidence. While osteoarthritis has been the focus of many recent studies, LDRT has demonstrated efficacy in treating other painful musculoskeletal conditions as well. 🚩 Tendinopathies, also known as enthesopathies, are one of those painful conditions. These conditions involve inflammation or degeneration at the point where tendons or ligaments attach to bone. Several studies have shown promising results. 🔷 I've created a table summarizing some of these studies.

https://lnkd.in/gvVwmmWF Favorable results in arthroscopic labral repair, even with acetabular chondral lesions, by using PRP and cell-based adjunct therapies.