INTERPHEX Global’s Post

What bioinformatics services does UGenome offer? Diagnostic/prognostic Biomarker discovery 09 Classifier development (ML/AI) - With gene signature and gene expression data, we build and optimize classifiers. - We evaluate classifiers (logistic regression, tree-based classifiers, XGBoost, Neural Nets, Genomic ensembling algorithms) to produce a number of classifiers and compare best performance. #ugenome, #ugenomeai, #ugenomebiotech, #bioinformatics, #biotech, #genetics, #science, #dna, #research, #genomics, #medicine, #immunology, #drugdiscovery, #datascience, #lifesciences, #biostatistics, #health, #pharma, #genomeannotation, #pharmacogenomics, #pharmacogenetics, #genomicmedicine, #sequencing, #dataanalysis, #machinelearning, #precisionmedicine, #metagenomics,

What bioinformatics services does UGenome offer? Diagnostic/prognostic Biomarker discovery 09 Classifier development (ML/AI) - With gene signature and gene expression data, we build and optimize classifiers. - We evaluate classifiers (logistic regression, tree-based classifiers, XGBoost, Neural Nets, Genomic ensembling algorithms) to produce a number of classifiers and compare best performance. #ugenome, #ugenomeai, #ugenomebiotech, #bioinformatics, #biotech, #genetics, #science, #dna, #research, #genomics, #medicine, #immunology, #drugdiscovery, #datascience, #lifesciences, #biostatistics, #health, #pharma, #genomeannotation, #pharmacogenomics, #pharmacogenetics, #genomicmedicine, #sequencing, #dataanalysis, #machinelearning, #precisionmedicine, #metagenomics,

The Genetic Research Cycle is at the core of advancements in genomic medicine. By connecting patients and families to scientific discoveries, we describe phenotypes, identify the genes responsible, and translate this knowledge into effective diagnostics, management, and therapy. This ongoing cycle not only helps us understand the mechanisms behind genetic diseases but also enables us to offer personalized care to improve patient outcomes. Each phase of the cycle—from identifying underlying genes to characterizing their impact—brings us closer to precision medicine, where treatments are tailored to individual genetic profiles. This is the future of healthcare, and it's unfolding today. #GenomicMedicine #GeneticResearch #PrecisionMedicine #ClinicalGenetics #HumanGenetics #ClinicalGenomics #PersonalizedCare #ResearchAndDevelopment #MedicalGenetics

Ephemeral Genes: Bacteria Rewrite Genetic Rules with Free-Floating DNA! #Mysummary The recent discovery by researchers from the Columbia University found that bacteria can create free-floating, transient genes outside of their chromosomal DNA, defying the traditional view that all genetic instructions are encoded within chromosomes. The key findings center around a bacterial defense mechanism involving an RNA molecule and a reverse transcriptase enzyme. This reverse transcriptase synthesizes DNA from RNA templates, creating ephemeral DNA sequences that function as fully operational genes. One such gene, named Neo, is part of the bacteria's antiviral response, preventing viral replication and protecting neighboring cells during an infection. #Mythoughts Now imagine if similar extrachromosomal genes are discovered in humans, it could lead to a complete rethinking of genetic regulation and coding, especially in contexts where genes may not be present in the genome itself but are instead transiently produced in response to specific conditions. HAPPY to hear your THOUGHTS and Stay POSITIVE! #Myinspiration "The important thing is not to stop questioning. Curiosity has its own reason for existence." Albert Einstein Link to the Science Magazine paper: https://lnkd.in/eVMqZr6g #microbiome #science #biology #pharma #health

What bioinformatics services does UGenome offer? 01 Customized Reference Genomes/Transcriptomes - Using pre-defined mutations or gene fusions, UGenome AI generates customized reference genomes/transcriptomes. - Customized genomic reference files enhance the sensitivity of detecting genomic alterations in next generation sequencing data and improve results from downstream bioinformatics analyses. #ugenome, #ugenomeai, #ugenomebiotech, #bioinformatics, #biotech, #genetics, #science, #dna, #research, #genomics, #medicine, #immunology, #drugdiscovery, #datascience, #lifesciences, #biostatistics, #health, #pharma, #genomeannotation, #pharmacogenomics, #pharmacogenetics, #genomicmedicine, #sequencing, #dataanalysis, #machinelearning, #precisionmedicine, #metagenomics,

Almaden Genomics recently enhanced its G.nome software, enabling the comprehensive processing, analysis, and visualization of single-cell RNA-seq data. This update encompasses advanced functionalities such as gene expression alignment and quantification per cell, Seurat clustering analysis, reference-based cell type annotation, and integrated parallelization capabilities. #genomics #rnaseq #dataanalysis

What bioinformatics services does UGenome offer? 01 Customized Reference Genomes/Transcriptomes - Using pre-defined mutations or gene fusions, UGenome AI generates customized reference genomes/transcriptomes. - Customized genomic reference files enhance the sensitivity of detecting genomic alterations in next generation sequencing data and improve results from downstream bioinformatics analyses. #ugenome, #ugenomeai, #ugenomebiotech, #bioinformatics, #biotech, #genetics, #science, #dna, #research, #genomics, #medicine, #immunology, #drugdiscovery, #datascience, #lifesciences, #biostatistics, #health, #pharma, #genomeannotation, #pharmacogenomics, #pharmacogenetics, #genomicmedicine, #sequencing, #dataanalysis, #machinelearning, #precisionmedicine, #metagenomics,

Understanding the Role of DNA Testing in Personalized Medicine. What is Personalized Medicine? Personalized medicine is the science that uses genetic profiles to determine if a specific person can benefit from a medical approach that will pro-actively determine prevention & treatment of conditions. What is a Gene ? Your gene is an amazing part of your DNA profile. It is a basic part of all individual’s DNA profile and is similar in almost all people. However, there are part of the genetic make-up that have genes that vary from person to person. This is what makes a person unique. How does the genetic DNA influence your health? Your genetic variations will influence your DNA changes. In certain rare situations, the variation of your genetic DNA can cause a medical condition. Some examples of these conditions are sickle cell anemia, Tay-Sachs and even a pre-disposition to cancer. If there is a family history of these genetic conditions, It is recommended that an individual should consult and test for the possibility of these genetic variations impacting them. SmarTest Labs: 501 N. Frederik Avenue, Suite 106, Gaithersburg Maryland 20874. Phone: 301-686-8566 Visit Website: https://lnkd.in/efbfQYkP #smartestlabs #DNAtesting #drugtesting #Alcoholtesting #DNA #genetic #Testing #Lab #Maryland

😎 Wow~ Our customers published a paper in Cell Discovery~ 🎉 👨🔬 👩🔬 Chemically induced dimerization (CID) is currently a widely used dimerization system that directly regulates protein function. However, CID systems still have many limitations. So how to overcome these limitations? 🧐 🤩 This study constructed integrated compact regulators of protein activity (iCROP), which can control signaling pathways and genome editing in vivo. The results provide powerful new tools for regulating or editing endogenous genes. 👏 👏 ✔ https://lnkd.in/gswxbj3Y   ✔ For more push, please follow #Twitter: https://lnkd.in/gntQ9qE7 ✔ Related Product Recommendation: #Asunaprevir (#BMS650032; https://lnkd.in/ghtJvzDs); #Rupintrivirvr (#AG7088; https://lnkd.in/gtx-XaTs); #Streptomycin (#Agrept; #Agrimycin; #StreptomycinA; https://lnkd.in/gs3m66Su); #Lopinavir (#ABT378; https://lnkd.in/g7kPU_wm); #Lipopolysaccharides (#LPS; https://lnkd.in/gCtd8NnF); #D-Luciferin (#D-(-)-Luciferin; #FireflyLuciferin; #BeetleLuciferin; https://lnkd.in/gC6QkE7B); #CellDiscov #iCROP #CID #GeneEditing #MCE #MedChemExpress

Genetics is driving the next wave of healthcare innovation, potentially holding the key to unlocking some of the most intractable diseases at their very source. We’re following the science, rooting our genetic medicines research in cutting-edge technology, collaboration, and the power of human genetics. From emerging modalities like gene editing to gene insertion to the innovative drug delivery and genetic payload technologies, we’re applying these new approaches to unearth discoveries for people who need them most. Read more from Aris Baras and Christos Kyratsous in our article with Forbes to see how we’re looking to shape the future of medicine. #ASGCT2024 https://bit.ly/3WCD2D0