Ira Weisberg’s Post

Acute pain is a sharp pain that comes on suddenly and is brought about by something specific. This type of pain may be short, no longer than six months, but can impact quality of life long-term. The pain tends to be related to a temporary illness or a soft-tissue injury, so it typically goes away after the illness or injury subsides. When it is not effectively relieved and treated, acute pain has a detrimental effect on all aspects of the quality of life. Studies have shown that it can produce anxiety and emotional distress in the lives of individuals, affect their general well-being negatively, and also inhibit their ability to perform daily family activities. Patients with acute pain need effective pain relief.  SofPulse will provide pain relief without narcotics. Additionally, using SofPulse will reduce inflammation and edema, with most patients experiencing a better wound-healing outcome. SofPulse is the only FDA-approved, technology-based, and patented pain relief product with a demonstrable ability to get patients back to their lives faster, with an improved quality-of-life benefit. SofPulse PEMF therapy treatment has been used in more than 20 thousand cases to manage acute pain and edema in both outpatient and home settings, offering patients a safe and effective pain management alternative. Contact us for more information. #painrelief #sofpulse #surgery #plasticsurgery #endonovo #endonovotherapeutics #healing #effectivepainrelief #nomoreopiods #painmanagement #managepain #fdacleared #noninvasive #edema #electroceuticals #pain #reducepain #veterans #veteranshealth #militarymedicine www.sofpulse.com

As seniors live longer, they have more years to develop chronic health conditions that often lead to surgery and other disorders needing effective pain management. SofPulse would represent a game-changing pain treatment for seniors where there is a need to find effective non-pharmacologic pain management methods. The US population is aging and the number of older adults undergoing surgery is increasing. In addition to worse traditional surgical outcomes (i.e., mortality, morbidity), older adults are prone to geriatric-specific complications such as postoperative delirium and functional decline. Aging affects every organ system, and these physiologic changes need to be recognized and incorporated into geriatric-specific post-operative care. Pain control in older adults requires adequate treatment of pain while simultaneously avoiding over-treatment with drugs. Uncontrolled pain is more common in older adults and is also a precipitating factor for postoperative delirium. A PEMF approach towards pain management – specifically SofPulse – would be a game changer in this market segment. Effective pain management, less edema and swelling, reduced inflammation, and getting back to your life all with no adverse event risks – there is nothing like this in the market. SofPulse will provide pain relief without narcotics or any drugs. Additionally, using SofPulse will address the underlying cause of pain - inflammation and edema. SofPulse is the only FDA-approved, technology-based, and patented pain relief product with a demonstrable ability to get you back to your life faster, with an improved quality-of-life benefit. SofPulse PEMF therapy treatment has been used in more than 20 thousand cases to manage acute pain and edema in in-patient, outpatient, and home settings, offering patients a safe and effective pain management alternative. Contact us for more information. www.sofpulse.com #painrelief #sofpulse #surgery #plasticsurgery #effectivepainrelief #painmanagement #edema #reducepain #veterans #veteranshealth #militarymedicine #seniors #seniormedicine #seniorcare #seniorhealth www.sofpulse.com

Pain robs an individual of their life. A patient may become anxious or depressed and may even want to end their life because of pain. This mostly results from being unable to do many of the things they could do without the pain. It robs them of their relationships with others, their ability to maintain employment, and sometimes the joy they have when they are without pain. According to a WHO (World Health Organization) study, people with persistent pain are four times more likely to suffer from anxiety or depression than individuals without pain, and more than twice as likely to have difficulty working and concentrating. When someone is in constant acute pain, the last thing they want to do is attend a friend’s backyard barbecue, a company party, neighborhood meetings, or even small gatherings with their family members or close friends. This often leads to a downward cycle of social isolation, further deteriorating feelings of joy and happiness, and exacerbating loneliness. A PEMF approach towards pain management – specifically SofPulse – is being seen as a game changer. Effective pain management, less edema and swelling, reduced inflammation, and getting back to your life all with no adverse event risks – there is nothing like this in the market. SofPulse provides pain relief without narcotics or any drugs. Additionally, using SofPulse will address the underlying cause of pain - inflammation and edema. SofPulse is the only FDA-approved, technology-based, and patented pain relief product with a demonstrable ability to get you back to your life faster, with an improved quality-of-life benefit. SofPulse PEMF therapy treatment has been used in more than 20 thousand cases, including a large number of breast and other cancer surgeries,  to manage acute pain and edema in in-patient, outpatient, and home settings, offering patients a safe and effective pain management alternative. Contact us for more information. #painrelief #sofpulse #surgery #plasticsurgery #effectivepainrelief #painmanagement #edema #reducepain #veterans #veteranshealth #militarymedicine #seniors #seniormedicine www.sofpulse.com

Intense acute pain afflicts millions of patients each year. Despite the recently increased focus on the importance of pain control, management of acute pain has remained suboptimal. One of the primary components of an acute pain service is the availability of round-the-clock pain services for patients requiring analgesia or counseling. Providing 24-hour pain services can be a costly and labor-intensive practice but is critical to ensuring the comfort of the majority of patients. SofPulse is the only FDA-cleared, non-invasive medical device offering round-the-clock, continuous pain therapy. SofPulse is programmed to administer its pain-relieving PEMF therapy continually to the site of the pain. Our patients report pain relief only hours after surgery – with no drugs. The benefits of the SofPulse acute pain therapy have been demonstrated in several studies including those reporting overall improvement in postoperative pain scores and patient satisfaction. Failure to administer appropriate analgesic treatment often results in worsening pain and more frequent hospital readmissions, adding to the already high economic burden associated with pain therapy. Moreover, the long-term consequences of under-treated acute pain should not be overlooked, since many patients with more severe acute postoperative pain may later suffer unnecessarily from chronic pain. The use of SofPulse post-operatively for facilitating early recovery and discharge, in addition to potentially reducing the risk of the development of chronic pain, is becoming the standard of care in many hospitals. If you or someone you know could use our help, please have them reach out to me at iweisberg@endonovo.com for a free consultation. Contact us for more information. #veterans #veteranshealth #pain #painrelief #painmanagement #armyhealth #navyhealth #sofpulse www.sofpulse.com

Our military heroes injured while on duty, veterans needing surgery as well as their families often experience substantial pain, which must be addressed before returning to active duty or returning to civilian life. The United States (US) military has instituted several guidelines and initiatives aimed at improving pain management by providing rapid access to medical care and developing interdisciplinary pain management strategies based on outcomes observed both in combat and hospital settings. For far too many years, military personnel undergoing surgery had only one option to manage their post-operative pain – drugs. Narcotics to be more specific. Far too often many of us suffered the consequences of drug therapy. As a society we traded off the reduction of pain for significant changes in the quality of our lives. Now, there is a clinically proven and FDA cleared alternative, SofPulseÒ (www.sofpulse.com). The market leader in the management of post-surgical pain. I speak with physicians, surgeons and patients every day about the journeys through managing pain. Almost without exception, the people I’m speaking to or someone they love (a sister, a mother, a best friend) either struggle with intractable pain or suffer pre-surgical anxiety because of the anticipation of pain. Pain patients are everywhere. So, I’m asking you: do you or someone you know planning on undergoing a surgical procedure such as a joint replacement, cardiac bypass surgery or another procedure? Are you or they anxious about the post-surgery recovery? Are you or they concerned about taking drugs to manage the pain? SofPulseÒ is the only available non-pharmaceutical, FDA cleared pain management device available in the country for the treatment of post-surgical pain. Our team of pain specialists will guide you or your loved one with a path towards a non-pharmaceutical recovery following surgery. SofPulseÒ has recently entered into a partnership to provide our therapy to all the military and VA hospitals throughout the US. If you or someone you know who could use our help, please have them reach to me at iweisberg@endonovo.com for a free consultation. Contact us for more information. #painreliief #sofpulse #surgery #effectivepainrelief # pain management # edema #veterans #veteranshealth # militarymedicine #effectivepainmanagement www.sofpulse.com

Clinical trials are not the only way to get phages to patients. An alternative is an approach that goes by a range of names: named patient use, expanded access, compassionate use… what they all cover is, to quote the European Medicines Agency, “a treatment option that allows the use of an unauthorised medicine. Under strict conditions, products in development can be made available to groups of patients who have a disease with no satisfactory authorised therapies”. The extraction of useful data from such studies is heavily outweighed by the need to treat the patient, and in some cases even recording such data can be unacceptable. But it does get therapeutic phages to patients, and there are quite a few cases where there have been positive results. One excellent example was a case series pubished on treating diabetic toe ulcers, where some extremely nasty conditions were resolved through the use of phages, which was work explicitly intended to progress matters towards clinical trials. Fish R, Kutter E, Wheat G, Blasdel B, Kutateladze M, Kuhl S. Compassionate Use of Bacteriophage Therapy for Foot Ulcer Treatment as an Effective Step for Moving Toward Clinical Trials. Methods Mol Biol. 2018;1693:159-170. doi: 10.1007/978-1-4939-7395-8_14. PMID: 29119440. Sacher J and Zheng J, Phage Therapy Collaboration and Compassionate Use. ” in D.R.Harper, S.T.Abedon, B.H. Burrowes, M.L.McConville eds. (2021). Bacteriophages: Biology, Technology, Therapy (2 volumes). Springer Nature, Vienna. ISBN 978-3319419855 #bacteriophage #phage #compassionate_use #expanded­_access #named_patient #phagetherapy #thephageadviser drh@thephageadviser.com

Pain is nearly universal, contributing substantially to morbidity, mortality, disability, and health care system burdens. Acute pain is often defined as the physiologic response and experience to noxious stimuli that can become pathologic, is normally sudden in onset, time-limited, and motivates behaviors to avoid actual or potential tissue injuries. Acute pain usually lasts for less than 7 days but often extends up to 30 days; for some conditions, acute pain episodes may recur periodically. In some patients, acute pain persists to become chronic. Acute pain is ubiquitous following surgery. The key decisional dilemma in acute pain management involves the selection of interventions to provide adequate pain relief, improve quality of life, improve function, and facilitate recovery while minimizing adverse effects and avoiding overprescribing of opioids. Evidence also suggests that adequate acute pain treatment may mitigate factors that promote the transition to chronic pain. However, shortcomings in acute pain care have been documented. In addition to the underlying cause of pain, patient factors that impact acute pain management include age, sex, race/ethnicity, pain severity, comorbidities (including mental health and substance use), genetic factors, pregnancy, or breastfeeding status. Timing of presentation and clinical setting can also influence acute pain management. For example, postoperative pain occurs at a specific point in time and is often managed with multimodal strategies in a monitored setting before discharge. A treatment that is effective for one acute pain condition and patient in a particular setting may not be effective in others. This is where SofPulse shines. SofPulse works regardless of the cause or pathology of the acute pain. In over 20 thousand cases to date, SofPulse has worked without any reported adverse events. SofPulse patients experience an effective treatment for their pain – and feel better quickly. Are you or someone you know planning on undergoing a surgical procedure such as a joint replacement, cardiac bypass surgery, or another procedure? Are you or they anxious about the post-surgery recovery? Are you or they concerned about taking drugs to manage the pain? SofPulse is the only available non-pharmaceutical, FDA-cleared pain management device available in the country for the treatment of post-surgical pain. Our team of pain specialists will guide you or your loved one with a path toward a non-pharmaceutical recovery following surgery. SofPulse has recently entered into a partnership to provide our therapy to all the military and VA hospitals throughout the US. If you or someone you know could use our help, please have them reach out to me at iweisberg@endonovo.com for a free consultation. Contact us for more information. #pain #painrelief #surgery #veteranshealth #veterans www.sofpulse.com

Clinical trials are not the only way to get phages to patients. An alternative is an approach that goes by a range of names: named patient use, expanded access, compassionate use… what they all cover is, to quote the European Medicines Agency, “a treatment option that allows the use of an unauthorised medicine. Under strict conditions, products in development can be made available to groups of patients who have a disease with no satisfactory authorised therapies”. The extraction of useful data from such studies is heavily outweighed by the need to treat the patient, and in some cases even recording such data can be unacceptable. But it does get therapeutic phages to patients, and there are quite a few cases where there have been positive results. One excellent example was a case series pubished on treating diabetic toe ulcers, where some extremely nasty conditions were resolved through the use of phages, which was work explicitly intended to progress matters towards clinical trials. Fish R, Kutter E, Wheat G, Blasdel B, Kutateladze M, Kuhl S. Compassionate Use of Bacteriophage Therapy for Foot Ulcer Treatment as an Effective Step for Moving Toward Clinical Trials. Methods Mol Biol. 2018;1693:159-170. doi: 10.1007/978-1-4939-7395-8_14. PMID: 29119440. Sacher J and Zheng J, Phage Therapy Collaboration and Compassionate Use. ” in D.R.Harper, S.T.Abedon, B.H. Burrowes, M.L.McConville eds. (2021). Bacteriophages: Biology, Technology, Therapy (2 volumes). Springer Nature, Vienna. ISBN 978-3319419855 #bacteriophage #phage #compassionate_use #expanded­_access #named_patient #phagetherapy #thephageadviser drh@thephageadviser.com

Keeping fingers crossed for #Metformin and #PIKASO, to hopefully see pain & function improve, and #joint_structure preserved with #preventive #treatment. Thx 🙏 to Jason Kim, PhD and to the Arthritis Foundation for kicking this off and for initiating this important #clinical_trial. Particularly interested to see elucidated whether the subtle structural changes in #articular_tissues occurring with #ACL_injury, caused by #trauma and/or altered #biomechanics and best assessible by quantitative #MRI #morphometry and #relaxometry, can be effectively #modified by #drug_treatment. - Ludwig Boltzmann Institute Arthritis and Rehabilitation - PROTO Horizon - #KANON_Study - Richard Frobell - Frank W. Roemer, M.D. - Ali Guermazi, MD, PhD - Saara Totterman, MD, PhD - Jose Tamez-Pena - Alan Brett PhD - Simon Herger - Annegret Mündermann - Nicholas Brisson - Univ.-Prof. Dr. Ing. Georg Duda - Mikael Boesen - Julien Freitag - Adam Culvenor - David Hunter https://lnkd.in/dYPyk9vR

TCC biomarker is vital for assessing complement response to medical devices or extra-corporeal circuits. Here, experts discuss how Svar TCC biomarker is used to investigate complement response in dialysis patients. Learn more! https://hubs.ly/Q02DSlQw0 #ComplementingLifeScience #AnswersinLifeScience #Complementsystem #Complementbiology #MedicalDevices #Hemocompatibility #ExtracorporealCircuits #Dyalisis #Catheter