Isomorphic Labs’ Post

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Congratulations to the team at Google DeepMind on launching #AlphaProteo, an AI system that could improve our understanding of biological processes. This system advances biological and health research, by supporting scientists in their creation of novel proteins that successfully bind to target molecules. Our scientists at Isomorphic Labs are excited to explore this model in application to drug design.

Google DeepMind

1,064,904 followers

Introducing AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules. 🧬 This research could help deepen our understanding of fundamental biology. Here’s how: 🔵 Protein binders are essential tools in drug development and biotech. They’ve already demonstrated potential in binding cancer cells, blocking viral infections and more. 🔵 AlphaProteo managed to generate candidates with strong binding to 7️⃣ diverse proteins related to infection, cancer, inflammation, and autoimmune disease. 🔵 AI for protein design has great potential - but more work is needed. We’re improving AlphaProteo’s success rate and will continue working with scientists to develop a responsible offering for the community. Find out more ↓https://dpmd.ai/4geFM0L

10 Comments

Samir EL ZEIN, PhD

Building advanced AI teams and solutions. CTO, genAI.

What do you do about the metallic active sites?

Jorge Zuniga, PhD

Protein Biochemist | Structural Biologist | Protein Engineer

Is it available to all Scientific community for free? Where?

Frédéric Célerse, PhD

Research scientist in AI for Chemistry

it looks like ubiquitin in this example ? 😅

1 Reaction

Rajan Bachra

Specialist R&D Life Science Recruiter for Biotechnology, Pharmaceutical and Medical Device Clients.

This tech is moving so quickly.. good job we have candidates keeping up 😉 Ellie Cockburn

1 Reaction

Prof Frederic Cadet

Co-founder & Chairman of the Board at PEACCEL

Thank You for sharing Isomorphic Labs

Saira Mohamed

Gene Therapy | Rare Disease | Longevity

Very interesting and fast moving tech!

Luke Usher

Open To New Opportunities

Connor Hadden

1 Reaction

Martin Trebbin

Principal Scientist & Assistant Professor, Uni Buffalo | Characterizing Atomic Structures of Biologics & Materials Dynamically | PhysicalChemistry •MaterialsScience •ProteinBiochemistry •PolymerScience •Nanotechnology

Inspiring!

Janine Swarbrick

Patent Director @ HGF Limited | Protecting and obtaining value from innovations in computing, software and physics including AI, digital health, FemTech and bioinformatics

Fascinating - Lauris Kemp this looks like your kind of science!

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Yurii Zakharchuk

Assistant of CEO @ OS-System | Connecting Businesses and Startups with Top-Tier Software Development Talent
1w
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This is literally what I wrote about a few posts ago — the AI revolution in medicine is happening quietly, but eventually, it will become very noticeable. Today, I saw the announcement about AlphaProteo — an AI system for designing novel proteins that bind more successfully to target molecules. This breakthrough could radically change the approach to treating diseases such as cancer, viral infections, and autoimmune diseases. AlphaProteo has already shown its effectiveness, creating proteins that bind to 7 different targets related to infections and inflammatory processes. Without a doubt, the potential of AI in protein design is immense, and although the work is just beginning, the results are already impressive. All of this shows that the future of medicine and biotechnology lies with artificial intelligence. #AI #medicine #biotechnology #artificialintelligence
Google DeepMind

1,064,904 followers
1w

Introducing AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules. 🧬 This research could help deepen our understanding of fundamental biology. Here’s how: 🔵 Protein binders are essential tools in drug development and biotech. They’ve already demonstrated potential in binding cancer cells, blocking viral infections and more. 🔵 AlphaProteo managed to generate candidates with strong binding to 7️⃣ diverse proteins related to infection, cancer, inflammation, and autoimmune disease. 🔵 AI for protein design has great potential - but more work is needed. We’re improving AlphaProteo’s success rate and will continue working with scientists to develop a responsible offering for the community. Find out more ↓https://dpmd.ai/4geFM0L
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Paul Bratcher

AI Expert | Transformation | Strategy | Digital | Futurist | CAIO | Startup Co-founder | Keynote Speaker | Make better not just faster
1w
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Ai but not generative Ai. You know one of the many other toolsets and research areas
Google DeepMind

1,064,904 followers
1w

Introducing AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules. 🧬 This research could help deepen our understanding of fundamental biology. Here’s how: 🔵 Protein binders are essential tools in drug development and biotech. They’ve already demonstrated potential in binding cancer cells, blocking viral infections and more. 🔵 AlphaProteo managed to generate candidates with strong binding to 7️⃣ diverse proteins related to infection, cancer, inflammation, and autoimmune disease. 🔵 AI for protein design has great potential - but more work is needed. We’re improving AlphaProteo’s success rate and will continue working with scientists to develop a responsible offering for the community. Find out more ↓https://dpmd.ai/4geFM0L
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Muchiu (Henry) Chang, PhD. Cantab (Cambridge, UK)

Consultant in Patent Intelligence and Engineering Management
1w
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Google DeepMind Technology is ONLY one of the three fundamentals, and NOT the key. The three universally basic IP based elements that make AI work are: 1. patented tools with high computational capability (fast chip/algorithm, quantum computer, etc.), 2. patented tools of energy technologies (battery/electricity power supply), and 3. copyrighted metadata. The importance of IPs of computational capability and energy have been taken for granted, though all are expensive.💰🤑💸 But the key is the copyrighted metadata, the treasure map curated by human for treasure hunting. Metadata is an enabler, a digital content, NOT a technology. Without metadata, NO data can be found/retrieved, even by the most advanced technologies, like AI, quantum computers, etc. https://lnkd.in/g-aJFnXR We are using our expertise/IP, a copyrighted multilingual metadata, to do what AI can't do in data analytics NOW. Do you or any contacts of yours need our expertise/IP? Thanks. AI 事實查核 (Chinese version): https://lnkd.in/eeVbdcza AI fact findings about AI (English version): https://lnkd.in/gwcPNUPP
Google DeepMind

1,064,904 followers
1w

Introducing AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules. 🧬 This research could help deepen our understanding of fundamental biology. Here’s how: 🔵 Protein binders are essential tools in drug development and biotech. They’ve already demonstrated potential in binding cancer cells, blocking viral infections and more. 🔵 AlphaProteo managed to generate candidates with strong binding to 7️⃣ diverse proteins related to infection, cancer, inflammation, and autoimmune disease. 🔵 AI for protein design has great potential - but more work is needed. We’re improving AlphaProteo’s success rate and will continue working with scientists to develop a responsible offering for the community. Find out more ↓https://dpmd.ai/4geFM0L
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Ute Blauth

Enterprise Account Executive at Google
1w Edited
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So impressive! Our incredible colleagues from DeepMind keep on pushing the boundaries of what is possible: This is the opposite of protein folding. Tells which protein sequences fold to a given functional structure. This is how #AI can impact lives. #DrugDiscovery #Machinelearning #AI
Google DeepMind

1,064,904 followers
1w

Introducing AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules. 🧬 This research could help deepen our understanding of fundamental biology. Here’s how: 🔵 Protein binders are essential tools in drug development and biotech. They’ve already demonstrated potential in binding cancer cells, blocking viral infections and more. 🔵 AlphaProteo managed to generate candidates with strong binding to 7️⃣ diverse proteins related to infection, cancer, inflammation, and autoimmune disease. 🔵 AI for protein design has great potential - but more work is needed. We’re improving AlphaProteo’s success rate and will continue working with scientists to develop a responsible offering for the community. Find out more ↓https://dpmd.ai/4geFM0L
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Bashar S.

MSc Bioinformatics Student
1w
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I just saw Google DeepMind's post about their new AI system, AlphaProteo, and it got me thinking... 🤔💡 My friend has been living with Facioscapulohumeral muscular dystrophy (FSHD) for years, and I often wonder about new research that could help. As I read about AlphaProteo's ability to design proteins that bind to specific targets, my mind started racing. 🧬🏃♂️ I can imagine so many potential applications for AlphaProteo across various diseases, but my thoughts immediately went to FSHD. What if we could use this to create proteins that bind to and inhibit DUX4 - the protein causing havoc in FSHD? The possibilities for FSHD research are exciting. AlphaProteo could revolutionize our understanding of DUX4 and its interactions, potentially uncovering new therapeutic targets we haven't even considered yet. By providing more precise and powerful research tools, it might accelerate the pace of discovery and bring us closer to effective treatments faster than we ever thought possible. Of course, there's still work to do. The next big challenge will be figuring out how to deliver these designer proteins into muscle cells throughout the body. But I'm optimistic that scientists can tackle this too! 🔬 Each advance brings us one step closer to transforming the lives of those with FSHD and other challenging diseases. The future of medical research with AI is bright, and it's fueled by the power of human ingenuity and compassion. 🌟💪🔬 #FSHD #FSHDHope #AIinMedicine #ResearchInnovation #AlphaProteo
Google DeepMind

1,064,904 followers
1w

Introducing AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules. 🧬 This research could help deepen our understanding of fundamental biology. Here’s how: 🔵 Protein binders are essential tools in drug development and biotech. They’ve already demonstrated potential in binding cancer cells, blocking viral infections and more. 🔵 AlphaProteo managed to generate candidates with strong binding to 7️⃣ diverse proteins related to infection, cancer, inflammation, and autoimmune disease. 🔵 AI for protein design has great potential - but more work is needed. We’re improving AlphaProteo’s success rate and will continue working with scientists to develop a responsible offering for the community. Find out more ↓https://dpmd.ai/4geFM0L
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Jhon Erick Rivera Monroy

Director Laboratorio Instrumental de Alta Complejidad - LIAC
1w
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The future is here
Google DeepMind

1,064,904 followers
1w

Introducing AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules. 🧬 This research could help deepen our understanding of fundamental biology. Here’s how: 🔵 Protein binders are essential tools in drug development and biotech. They’ve already demonstrated potential in binding cancer cells, blocking viral infections and more. 🔵 AlphaProteo managed to generate candidates with strong binding to 7️⃣ diverse proteins related to infection, cancer, inflammation, and autoimmune disease. 🔵 AI for protein design has great potential - but more work is needed. We’re improving AlphaProteo’s success rate and will continue working with scientists to develop a responsible offering for the community. Find out more ↓https://dpmd.ai/4geFM0L
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Daniel Peterson

Focused on neuroscience research
1w
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“Trained on large amounts of protein data from the Protein Data Bank (PDB) and more than 100 million predicted structures from AlphaFold, AlphaProteo has learned the myriad ways molecules bind to each other. Given the structure of a target molecule and a set of preferred binding locations on that molecule, AlphaProteo generates a candidate protein that binds to the target at those locations.” #AI #proteinbinding #alphaproteo #alphafold
Google DeepMind

1,064,904 followers
1w

Introducing AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules. 🧬 This research could help deepen our understanding of fundamental biology. Here’s how: 🔵 Protein binders are essential tools in drug development and biotech. They’ve already demonstrated potential in binding cancer cells, blocking viral infections and more. 🔵 AlphaProteo managed to generate candidates with strong binding to 7️⃣ diverse proteins related to infection, cancer, inflammation, and autoimmune disease. 🔵 AI for protein design has great potential - but more work is needed. We’re improving AlphaProteo’s success rate and will continue working with scientists to develop a responsible offering for the community. Find out more ↓https://dpmd.ai/4geFM0L
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Umar Mohammad

Senior at Harmony School of Endeavor – Austin
1w
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As AI systems grow more powerful, it is clear that they will become crucial companions to cutting-edge research in the natural sciences, whether it is physics, biology, or chemistry.
Google DeepMind

1,064,904 followers
1w

Introducing AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules. 🧬 This research could help deepen our understanding of fundamental biology. Here’s how: 🔵 Protein binders are essential tools in drug development and biotech. They’ve already demonstrated potential in binding cancer cells, blocking viral infections and more. 🔵 AlphaProteo managed to generate candidates with strong binding to 7️⃣ diverse proteins related to infection, cancer, inflammation, and autoimmune disease. 🔵 AI for protein design has great potential - but more work is needed. We’re improving AlphaProteo’s success rate and will continue working with scientists to develop a responsible offering for the community. Find out more ↓https://dpmd.ai/4geFM0L
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Lisa Monluc

Biochemistry PhD Candidate at FSU
1w
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How cool is it to be able to design peptide drugs to intervene with protein-protein interactions! AI has made a revolutionary impact to how we discover drugs by implementing often slow wet-lab experiments as verification process. I believe this tool will become more accurate as our understanding of protein-protein interactions improve.
Google DeepMind

1,064,904 followers
1w

Introducing AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules. 🧬 This research could help deepen our understanding of fundamental biology. Here’s how: 🔵 Protein binders are essential tools in drug development and biotech. They’ve already demonstrated potential in binding cancer cells, blocking viral infections and more. 🔵 AlphaProteo managed to generate candidates with strong binding to 7️⃣ diverse proteins related to infection, cancer, inflammation, and autoimmune disease. 🔵 AI for protein design has great potential - but more work is needed. We’re improving AlphaProteo’s success rate and will continue working with scientists to develop a responsible offering for the community. Find out more ↓https://dpmd.ai/4geFM0L
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Tanaka Gareth Makuza

QA/QC Lab Tech at Prodairy | Biotech | Lean Six Sigma Black Belt | Continuous Improvement | Diploma in ISO Standards | Google Certified Project Manager | Certified Generative AI Expert
1w Edited
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Hey biotechnologists, Checkout AlphaProteo dropped by Google DeepMind just now! AlphaProteo is an AI for novel protein design. Unlike AlphaFold which just predicts the 3D structure of proteins and protein interactions, AlphaProteo can go a step further and design novel proteins. These two AI tools provide a glimpse of an exciting future for protein engineering. #AI #proteinengineering #AlphaProteo
Google DeepMind

1,064,904 followers
1w

Introducing AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules. 🧬 This research could help deepen our understanding of fundamental biology. Here’s how: 🔵 Protein binders are essential tools in drug development and biotech. They’ve already demonstrated potential in binding cancer cells, blocking viral infections and more. 🔵 AlphaProteo managed to generate candidates with strong binding to 7️⃣ diverse proteins related to infection, cancer, inflammation, and autoimmune disease. 🔵 AI for protein design has great potential - but more work is needed. We’re improving AlphaProteo’s success rate and will continue working with scientists to develop a responsible offering for the community. Find out more ↓https://dpmd.ai/4geFM0L
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