International Society for Stem Cell Research’s Post

Improve the quality and reproducibility of your research! Apply standardized reporting practices for publishing results with hPSCs. 📌 Request a free wallchart for a quick reference of the ISSCR Standards for Human Stem Cell Use in Research: https://bit.ly/3yv5EnU International Society for Stem Cell Research #StemCellResearch

On this day in 2019, we debuted the Integrated Mitotic Stem Cell - the first comprehensive view of human stem cell division. Explore the tool at https://lnkd.in/gVhzkYb6

Hope is on the horizon for Parkinson's disease 🕊️🔬. With stem cell advancements, we're closer than ever to transforming how we treat this condition. Join us on this journey of innovation and discovery, where each step forward brings us nearer to a future free of Parkinson's challenges. Explore how stem cells are becoming a beacon of hope. Learn more by clicking the link in our bio. #FightParkinsons #stemcellhope International Stem Cell Institute 📞 (941)-867-7224 🌐 https://lnkd.in/dxCJCXmc #stemcells #stemcellresearch #stemcelltherapy #regenerativemedicine #cellulartherapy #stemcelltransplant #stemcelltreatment #chronicconditionrelief

Well done team! I happened to be at BioServe Space Technologies yesterday and witnessed on-orbit operation for the Human Brain Organoid Models for Neurodegenerative Disease & Drug Discovery (HBOND) study by my colleague and good friend astronaut Michael Barratt. The study investigates the mechanisms behind neuroinflammation, a common feature of neurodegenerative disorders, and test the response of several drugs against these effects. #stemcells #organoids #neurodegenerativedisease #parkinson #alzheimer #drugdevelopment #multiplesclerosis

Delve deeper into groundbreaking research from LKCMedicine, led by Assistant Professors Xia Yun and Jia Nee Foo, along with the dedicated research team including Research Associate Liu Meng and Research Fellow Dr Zhang Chao. Shedding light on potential breakthrough therapies for Polycystic Kidney Disease (PKD), the study cultivates 'mini kidneys' in the lab and implants them into live mice, uncovering crucial insights into PKD's metabolic dysfunctions. Explore the published study in Cell Stem Cell to learn more about the innovative approach and its implications for advancing PKD treatment. Read more: https://lnkd.in/gkhkPDxa #ResearchInnovation #LKCMedicine #PKDResearch

LEARN another powerful application of FREE RAPID STEM CELL CALCULATORS (https://lnkd.in/eKMZmqjs) for your tissue stem cell studies. Review the evidence in Chopra et al. 2023: https://lnkd.in/gV28iVhB REPOST TO SHARE!

We don’t put enough merit into this. Once upon a time, I was asked to perform karyotyping on our iPS cell lines. It’s expensive so not all labs routinely do it, but it should be done every 10 passages. iPSCs are very sensitive and their chromosomes can change in an instant. One of my cell lines were showing beautifully round colonies with distinct edges. Compared to another cell line that was barely attaching, it’s attachment efficiency and fold expansion were great. I thought they’ll be karyotypically fine 😀 Boy was I wrong! All 20 of the cells were mutated! It was actually the poorly growing ones that showed less karyotypic abnormalities. 🤮😑 Arguably, that they grew well is like they had cancer cell like properties 🤔 A few points: - Don’t be fooled by your eyes with your day to day cell culture. Always do the actual tests. - Treat iPSCs with the utmost care. Whilst I said the poorly growing ones had less abnormalities, they had only been in culture for 2 passages and still turned up issues. - Stop assuming that at your early stage of research, that it should be OK. The healthier cells were clearly performing very differently to the unhealthy ones. If they don’t behave normally in controlled lab conditions, they won’t behave normally in an animal or human trials. - If you do the testing, you can submit the reports to a journal in the initial stages. They will have more confidence in your results moving forward. Thanks to Prof. Laurie A. Boyer for teaching me all the above!

Thanks to advancements in stem cell research, particularly the recognition of the regenerative properties of Mesenchymal Stem Cells (MSCs), Adult Stem Cell Banking has become a versatile and promising avenue for accessing personalized healthcare and future therapeutic interventions. In our latest article, we describe the Stem Cell Banking process in detail and explain how it may greatly increase the potential for positive results when therapeutic application is necessary. https://lnkd.in/gwPpPt_k

🆕 We are more than happy to welcome to our Institute Dr. Vincenzo Calvanese, a well-recognized and consolidated researcher on #StemCell biology. Dr. Calvanese will lead the new “Blood Stem Cell Identity” group. They will try to understand which molecular features and regulatory processes identify a #BloodStemCell, a fundamental knowledge to advance in many areas, like haematopoietic stem cell transplant, one of the few successful clinical applications of stem cells today. Calvanese and his team join forces with IJC in the fight against #leukaemia 💪 Know more about his research in this article ⬇ https://lnkd.in/eWS9BR2n

In response to the recent New York Times articles exposing the significant shortcomings of traditional cord blood banks, VitalCells is setting a new industry standard by providing parents with live mesenchymal stem cells (MSCs) from their newborn's umbilical cord tissue and blood. This innovative approach ensures families have tangible, usable stem cells for regenerative medicine, addressing the critical issues highlighted in the exposé. Check out our latest blog to learn more about how VitalCells stands out in the field of stem cell banking by offering a more tailored and reliable solution for many families📣 ➡ https://lnkd.in/gJ55QpxB #VitalCellsPoweredByAmericanCellTechnology