Jaiswal Pharma’s Post

Top 5 Drug Interactions You Should Know 💊 Understanding drug interactions is vital for safe and effective treatment. Here's a quick guide to some common interactions that everyone should be aware of: 1.Warfarin and Aspirin 🩸 Interaction: Increases risk of bleeding. Explanation: Both medications thin the blood but through different mechanisms, leading to a heightened risk of serious bleeding events. 2.Statins and Grapefruit Juice 🍇🍹 Interaction: Raises statin levels in the blood. Explanation: Grapefruit juice inhibits a key enzyme that metabolizes statins, increasing their blood concentration and the risk of side effects like muscle pain. 3.ACE Inhibitors and Potassium Supplements 🧂❤️ Interaction: Leads to high potassium levels. Explanation: ACE inhibitors can increase blood potassium, and additional supplements might push these levels to dangerous heights, affecting heart rhythm. 4.Antibiotics and Calcium-Rich Foods 🥛💊 Interaction: Decreases antibiotic effectiveness. Explanation: Calcium in foods can bind with certain antibiotics, preventing them from being properly absorbed. 5.SSRIs and MAOIs 🧠⚠️ Interaction: Can cause serotonin syndrome. Explanation: Taking these two types of antidepressants together can lead to dangerously high serotonin levels, resulting in severe symptoms. 👉 Awareness of these interactions can prevent adverse effects and improve the safety of treatment plans. Always consult with your healthcare provider to ensure you're managing medications appropriately. #Pharmacology #Healthcare #DrugInteractions #PatientSafety #MedicationManagement #PharmacyTips #HealthEducation #ClinicalPharmacy #HealthAwareness #MedicalAdvice #PatientCare #HealthcareInnovation #PharmaFacts

Vitamin D for Restless Legs?--Did taking vitamin D reduce the severity of restless legs syndrome in women? See what a recent study found in the Restless legs syndrome (RLS) section of our Vitamin D Supplements Review, which includes our Top Picks for vitamin D. https://ow.ly/wgtl50SXIgx

Insulin detemir, sold under the brand name Levemir among others, is a long-acting modified form of medical insulin used to treat both type 1 and type 2 diabetes. It is used by injection under the skin. It is effective for up to 24 hours. Insulin detemir was approved for medical use in the European Union in June 2004, and in the United States in June 2005. It is on the World Health Organization's List of Essential Medicines. In 2020, it was the 124th most commonly prescribed medication in the United States, with more than 5 million prescriptions. It is an insulin analogue in which a fatty acid (myristic acid) is bound to the lysine amino acid at position B29. It is quickly absorbed after which it binds to albumin in the blood through its fatty acid at position B29. It then slowly dissociates from this complex. Here you can see a recent crystal structure of insulin detemir, showing the binding of myristic acid to the complex (PDB code: 8IPZ) Rendering by Francisco J. Enguita made with #proteinimager https://lnkd.in/dC8sqp-U #molecularart #insulin #detemir #myristic #diabetes #xray

#OBRxBrands #OurWorkWednesday JANUVIA is a dipeptidyl peptidase-4 (DPP-4) inhibitor indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. To Learn More: https://lnkd.in/eFbFMxPx #OptiBrand #OptiBrandRx #OBRx #OWW #Pharma #PharmaMarketResearch #PharmaStrategy #strategy #marketresearch #getmore #PharmaExperts 

In India, there is a common fear that whey damages the kidneys. What many don't know is that pharmaceutical companies sell whey-based products for chronic kidney disease (CKD) patients, which are loaded with sugars in the form of maltodextrin and fructose. These products also list corn oil as the first ingredient. Corn oil has been proven detrimental to cardiovascular health, as highlighted in the Minnesota Coronary Experiment. (Ref: https://lnkd.in/d8NKSqNh ) This harmful formulation is given to CKD patients who often already suffer from diabetes and hypertension. Such products will only worsen their conditions, increasing the need for more insulin or blood pressure medications. When will we learn the correct nutrition for CKD patients? Anup Singh Mandar Gadre, Ph.D.

⚠ - Small rant coming...just a heads up. I am reaching peak fatigue with people promoting their products as the equivalent to GLP1-receptor agonists. These drugs (semaglutide, tirzepatide, liraglutide, etc) bind to and activate the GLP-1 receptor in a manner similar to GLP-1 you make in your on body. This is like when we give estrogen to women in menopause or prednisone, a synthetic glucocorticoid that binds to cortisol receptors, to people with a serious inflammatory reaction. Compounds that stimulate the release of a hormone are not the same as receptor agonists. Lots of things can stimulate release of hormones, or even have hormone-like activity, but that does not per se make them effective. I am not saying that some products that increase GLP1 release are not helpful for metabolic health and weight management, but it's not the same mechanism and we should not anticipate the same effect. Consider that the primary things that stimulate the release of insulin are sugars, free fatty acids, and amino acids - but we would not equate these to replacing insulin in someone with diabetes. Just some food for thought. #GLP #weightmanagement #weightloss #notnaturesozempic

💊 Drug-Induced Liver Injury (DILI) – Stay Safe, Stay Informed The liver plays a vital role in detoxifying substances, but it can be overwhelmed when medications are taken carelessly. The cartoon below humorously highlights a serious issue: when your liver is "under attack" from improper drug use. ⚠️ Why Should You Care? Regular use of medications without proper consultation can harm your liver. Some medications, even over-the-counter ones, have hepatotoxic potential. Polypharmacy (using multiple drugs) increases the risk of drug interactions. 🩺 What Can You Do? 1. Always consult a healthcare professional before starting or stopping any medication. 2. Avoid self-medication, especially with painkillers, antibiotics, and herbal supplements. 3. Monitor liver function when on long-term therapies. 4. Be informed about possible side effects of prescribed drugs. Your liver matters! Protect it by being cautious with medications. #DrugSafety #LiverHealth #Pharmacovigilance #StayInformed #HealthAwareness #BeSafe

💊 Drug-Induced Liver Injury (DILI) – Stay Safe, Stay Informed The liver plays a vital role in detoxifying substances, but it can be overwhelmed when medications are taken carelessly. The cartoon below humorously highlights a serious issue: when your liver is "under attack" from improper drug use. ⚠️ Why Should You Care? Regular use of medications without proper consultation can harm your liver. Some medications, even over-the-counter ones, have hepatotoxic potential. Polypharmacy (using multiple drugs) increases the risk of drug interactions. 🩺 What Can You Do? 1. Always consult a healthcare professional before starting or stopping any medication. 2. Avoid self-medication, especially with painkillers, antibiotics, and herbal supplements. 3. Monitor liver function when on long-term therapies. 4. Be informed about possible side effects of prescribed drugs. Your liver matters! Protect it by being cautious with medications. #DrugSafety #LiverHealth #Pharmacovigilance #StayInformed #HealthAwareness #BeSafe