National Cerebral and Cardiovascular Center’s Post

【 Understanding the Risks: How Brain Vessel Health Influences Bleeding in Patients on Blood Thinners 】 Researchers at the National Cerebral and Cardiovascular Center in Suita, Japan, conducted a study published in 'Ann Neurol. 2023 Dec 25,' aimed to understand how cerebral small vessel disease (SVD) affects the risk of bleeding in patients taking blood-thinning medications. Over 5,000 patients with heart or brain vessel diseases from various hospitals in Japan were followed, tracking their health and treatment with drugs that prevent blood clots. Using MRI scans, the team calculated each patient's total SVD score, a measure of the disease's severity in the brain's small vessels. They then observed these patients over time to see how often major bleeding or clot-related problems (ischemic events) occurred. The findings revealed a clear pattern: as the SVD score increased, so did the rate of major bleeding and stroke-like events. Particularly, patients with the highest SVD score (4) were significantly more likely to experience severe bleeding within the brain and other parts of the body compared to those with a score of 0. In summary, the study suggests that the severity of cerebral SVD is a helpful indicator for doctors to consider when prescribing blood-thinning medications. A higher SVD score means a higher risk of bleeding, which can guide safer treatment decisions. This information is crucial for balancing the benefits of preventing clots with the risks of bleeding, especially in patients with underlying vascular conditions. https://lnkd.in/gw4HzDgW

Cerebral small vessel disease: predictive for intracranial hemorrhage and probably for extracranial bleeding during antithrombotic therapy|News Releases|About NCVC|National Cerebral and Cardiovascular Center

Cerebral small vessel disease: predictive for intracranial hemorrhage and probably for extracranial bleeding during antithrombotic therapy|News Releases|About NCVC|National Cerebral and Cardiovascular Center

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