JCDD MDPI’s Post

#Accutane_Series: Part_1: As a doctor, pay attention to these #five points when prescribing a #Accutane (#Isotretinion) medication: Accutane Disease Interactions: 1️⃣ 𝗜𝗻𝘁𝗿𝗮𝗰𝗿𝗮𝗻𝗶𝗮𝗹 𝗵𝘆𝗽𝗲𝗿𝘁𝗲𝗻𝘀𝗶𝗼𝗻: Can cause pseudotumor cerebri, leading to symptoms like papilledema, headache, nausea, and visual disturbances. Refer patients experiencing these symptoms to a neurologist, discontinue retinoid permanently if confirmed. 2️⃣ 𝗣𝘀𝘆𝗰𝗵𝗶𝗮𝘁𝗿𝗶𝗰 𝗱𝗶𝘀𝗼𝗿𝗱𝗲𝗿𝘀: Associated with depression, psychosis, and rarely, suicidal ideation. Administer with caution in patients with preexisting psychiatric conditions, consider therapy withdrawal, and ensure evaluation and follow-up. 3️⃣ 𝗢𝘀𝘁𝗲𝗼𝗽𝗼𝗿𝗼𝘀𝗶𝘀: May negatively impact bone mineral density, particularly in adolescents. Caution advised in patients with a history of childhood osteoporosis or other bone disorders. 4️⃣ 𝗘𝗹𝗲𝘃𝗮𝘁𝗲𝗱 𝘀𝗲𝗿𝘂𝗺 𝘁𝗿𝗶𝗴𝗹𝘆𝗰𝗲𝗿𝗶𝗱𝗲𝘀: Linked to increases in triglycerides and cholesterol, with potential cardiovascular risks and risk of fatal pancreatitis. Monitor lipid levels before and during therapy, especially in high-risk patients. 5️⃣ 𝗟𝗶𝘃𝗲𝗿 𝗱𝗶𝘀𝗲𝗮𝘀𝗲: Linked to liver enzyme elevations and toxic hepatitis. Administer with caution in patients with liver disease, monitor liver enzymes regularly. #Accutane #isotretinion #medication #medicationsafety #pharmacy #communitypharmacy #pharmacist 📍𝗥𝗲𝗳𝗲𝗿𝗲𝗻𝗰𝗲: https://lnkd.in/eJaWM8eE

Crohn's disease, a chronic inflammatory disorder primarily impacting the small intestine with potential involvement of the large intestine, is influenced by immune factors and often has a genetic predisposition. Assessment findings typically encompass abdominal cramps, chronic diarrhea, fever, nausea, weight loss, and pain localized in the right lower quadrant. Nursing diagnoses commonly associated with Crohn's disease include anxiety, diarrhea, imbalanced nutrition, and acute pain. Diagnostic modalities such as X-rays, colonoscopy, and fecal tests are employed for accurate diagnosis. Treatment modalities encompass a spectrum ranging from pharmacological management to dietary adjustments and, in severe cases, surgical interventions such as colectomy with ileostomy. Nursing interventions entail vigilant monitoring of gastrointestinal status, administration of prescribed medications, provision of nutritional support, and diligent postoperative care for patients undergoing surgery. Educational endeavors aimed at patients should focus on imparting comprehensive understanding of the disorder, proper medication adherence, self-care strategies for managing ileostomy, stress management techniques, and vigilant recognition of symptomatology for timely intervention. Effective management of Crohn's disease necessitates a multifaceted approach involving collaboration between healthcare professionals and patients to optimize outcomes and enhance quality of life. *let's connect for more knowledge sharing* #healthcare #health #linkedin #linkedinlearning #study #knowledge #research #medicine #medical #medicina #wecan #europe #asiapacific #asia #antarctica #india #southafrica #doctor #nurses #mediation #drugdevelopment #drugsafety #ingo #ngo

Incorporating the use of the Clinical Frailty Scale in clinical practice can help to identify patients with cirrhosis who may be at a higher risk of developing hepatic encephalopathy. https://brnw.ch/21wGWKA

Hypertension is the leading cause of preventable cardiovascular deaths in Ghana, affecting 34% of the population, with over 60% unable to access treatment. A recent article by the Ghanaian Society of Cardiology, Stroke Association Supportnetwork-Ghana (SASNET-GHANA), and the World Heart Federation in the Ghana Medical Journal highlights key roadblocks to hypertension management, including insufficient funding and healthcare capacity. Based on a roundtable discussion, the article outlines actionable steps to tackle these barriers and improve cardiovascular health across the country. Find the article here: https://lnkd.in/ejvS46Ea.

After more than four years in the making, with the help of a great interdisciplinary team and support from a pilot grant from UR Medicine, our paper is finally out. Here is the gist: The prevalence of prediabetes and type 2 diabetes is high in people with serious mental illness on second-generation antipsychotics, and oral glucose tolerance testing has the potential to identify these patients much earlier. Insulin resistance, higher triglyceride levels, pulse rates, and waist/hip ratios are associated with an increased risk of prediabetes and type 2 diabetes. Finally, unhealthy diet habits translate into worse metabolic profiles, and daily step counts are closely correlated with CRP levels, a well-known cardiac risk marker. All of the above findings emphasize the need and potential power of lifestyle measures to improve those markers. With the same interdisciplinary team, we are working hard to improve the metabolic health of folks with serious mental illness in our integrated diabetes clinic at the UR MIPS-PC site (Medicine-In-Psychiatry-Service Primary Care).

https://lnkd.in/g4Rr5_YP Article title: Correlation of Cardiac Sympathetic Nervous System Dysfunction with Diastolic Left Ventricular Dysfunction in Patients with Controlled Hypertension   Author(s): Elsayed Abo-salem*; Mouhamad Abdallah; Mohamed Effat; Said Alsidawi; Myron Gerson   Journal: Archives of Clinical Hypertension   Journal ISSN: 2640-771X Introduction: Sympathetic nervous system activity is increased in patients with systemic hypertension. Angiotensin converting enzyme inhibitors can effectively control hypertension without a reflex sympathetic stimulation. However, limited data are available about the role of sympathetic dysfunction in the pathophysiology of diastolic dysfunction among patients with controlled hypertension receiving angiotensin converting enzyme inhibitors. #ArterialBloodPressure #ArterialHypertension #BloodPressureMonitoring #BloodPressureVariability #CardiovascularRisks #CentralBloodPressure #HighBloodPressure #HypertensionDuringPregnancy #HypertensionInChildren #HypertensionInNewborn #HypertensionManagement #HypertensionNeonate #HypertensionNursing #HypertensionNutrition #HypertensionRiskFactors #HypertensionTreatment #Peertechz #PeertechzPublications #HypertensiveCrisis #HypertensiveEmergency #IdiopathicIntracranialHypertension #InducedHypertension #IntracranialHypertension #LowBloodPressure #PersistentPulmonaryHypertension #PortalHypertension #ProtopulmonaryHypertension #PulmonaryHypertension #RenalDisorders #TraumaticIntracranialHypertension

Thanks for sharing! Crohn’s diagnosis should be considered during some specific clinical presentations, including acute abdominal pain. To be more discrete, right lower quadrant abdominal pain. Missed diagnosis and unnecessary surgical procedures might cause post-operative complications, including enteric fistulaes. Also, I would recommend replacing the video, with a more relevant one with the Crohn Disease, including different strictruoplasty procedures #Crohn_Disease #stricturoplasty #Surveillence_guidelines Deepak Pandey

THE SILENT KILLER Hypertension, often called the silent killer, is a serious condition that frequently presents no symptoms. Recently, I had a conversation with a friend in his mid-thirties about his health. When I asked him about his last blood pressure check, he mentioned it was over six months ago. I advised him to visit a nearby pharmacy for a quick check-up. To his surprise, his blood pressure was 160/100 mmHg. He had no idea his blood pressure was high, especially since neither he nor his family had been diagnosed with hypertension. During my research on hypertension, I discovered some surprising differences in the guidelines. According to the American College of Cardiology (ACC) and the American Heart Association (AHA), stage 1 hypertension is defined as a systolic blood pressure (SBP) of 130-139 mmHg or a diastolic blood pressure (DBP) of 80-89 mmHg. In contrast, the European Society of Hypertension considers stage 1 hypertension to start at 140/90 mmHg. What last did you check your blood pressure?