Leading the way in collaborative compounds, drug discovery and targeted therapeutics - what a joy to share that the joint effort of Moderna & Carisma Therapeutics has yielded the first in a series of candidates. This nomination leverages mRNA-based in vivo CAR-M to develop a novel cell therapy targeting GPC3 in solid tumors - and which is known to be highly expressed in hepatocellular carcinoma. "HCC is the most prevalent type of liver cancer and the fastest-rising cause of cancer-related death in the U.S." Let's bring forward some new options for patients! #HCC #LiverCancer #PatientPotential #mRNA #Macrophage #Monocyte #GPC3 #Glypican3 #collaboration #drugdiscovery #targetedtherapeutics #celltherapy #celliconvalley #immunotherapy #solidtumor #NasdaqCARM
We are excited to announce the nomination of the first Development Candidate under our collaboration with Moderna, Inc. The Development Candidate is an in vivo CAR-M targeting Glypican-3 and is designed to treat solid tumors, including hepatocellular carcinoma, the most prevalent type of liver cancer and the fastest-rising cause of cancer-related death in the U.S. Read more in the press release here: https://lnkd.in/gpeaEx_v #Immunotherapy #CancerResearch #SolidTumors #LiverCancer #HCC