Joslyn Chaiprasert-Paguio’s Post

We are calling for papers for our upcoming issue. Contact me if you want to contribute! 😘 🥁 Title: Tau Protein Pathology in Alzheimer's Disease 📌Instructions: https://lnkd.in/dYcUY7xe 📩Submission: https://lnkd.in/gTKzH2ry ⌛ Deadline: 30 August 2024 📡 Journal of Integrative Neuroscience 📞 Any Questions: Amy.wang@imrpress.com The main goal of this topic is to examine the role of abnormal tau protein accumulation in Alzheimer's disease, including its spread throughout the brain, and its implications for disease progression and therapeutic targeting. This can include novel genetic, cellular, animal, neuroimaging, psychological and behavioral research.  #callforpapers #Review #OriginalResearch #BrainHealth #neuroscience #Tauprotein #Tau #alzheimers #neuroresearch #NeurodegenerativeDiseases #InnovationInResearch #Neurodegeneration #AlzheimersDisease

🧠 Exciting Discovery in Memory Formation: 🌟 A recent study published in Nature sheds light on the fascinating connection between DNA damage,repair, and long-term memory formation. Researchers found that when memories are created, brain cells experience DNA breaks, triggering an inflammatory response crucial for memory consolidation. This groundbreaking research, led by Jelena Radulovic and team, uncovers the intricate mechanisms underlying memory encoding and retention. The study highlights the role of the TLR9 protein in the inflammatory response to DNA damage, suggesting that our own DNA acts as a signaling system for memory storage. Deleting the TLR9 gene in mice impaired long-term memory recall, emphasizing the importance of DNA repair in memory processes. Understanding these internal mechanisms not only enhances our knowledge of memory formation but also offers insights into neurodegenerative diseases like Alzheimer's. This research opens new avenues for exploring the complexities of memory at a cellular level. Read more about this exciting study here: https://lnkd.in/gtac6fTs #MemoryFormation #Neuroscience #DNADamage #InflammatoryResponse #ResearchBreakthrough 🧬🔬

#ACROHighlights [Featured Product] Modeling Alzheimer's Disease with PFFs and Cerebral Organoids 🧠🔬 Alzheimer's disease (AD) research is advancing rapidly thanks to innovative disease models. Pre-formed Fibrils (PFFs) are at the forefront, mimicking the seeding and propagation of pathogenic proteins in both in vivo and in vitro models. This breakthrough approach is paving the way for deeper insights into understanding and treating AD. By introducing PFFs into brain organoid models, researchers achieve a significant leap in AD research. This method closely replicates the pathological protein seeding and propagation seen in AD, creating more realistic and representative disease models. 🔗 Explore Aneuro to Empower Your Research: https://smpl.is/9aryw #AlzheimersResearch #BiotechInnovation #DiseaseModeling #Neuroscience #Aneuro

Friend or foe: The role of stress granule in neurodegenerative disease Stress granules are temporary dynamic cellular structures that form in response to stress, primarily composed of RNA and RNA-binding proteins. They can interact with several other organelles. While normally protective, their dysfunction is implicated in neurodegenerative diseases, such as ALS, FTD, HD, Alzheimer's, and Parkinson's. This review explores stress granules' formation, composition, and role in cellular stress responses, as well as their complex involvement in both preventing and promoting neurodegeneration. Understanding this intricate relationship is crucial for developing new treatments for these debilitating diseases. The article was published in Neuron: https://lnkd.in/esJ-PYVQ. #genetics #genomics #precisionmedicine #genomicmedicine #brain #neurology #neurodegeneration #neuroscience #als #ftd #huntington #parkinson #alzheimer #stress #rna #biomarkers #therapeutics #biotechnology #innovation #research #science #sciencecommunication

🧠 Exciting Breakthrough in Alzheimer's Research 🌟 Researchers have identified five distinct subtypes of Alzheimer's disease, a major leap forward in understanding and treating this complex condition. This discovery, involving an international team of neuroscientists, reveals unique molecular processes and genetic profiles for each subtype. This new perspective on Alzheimer's disease opens the door to more targeted and effective treatment strategies. It's not just a single disease; it's five distinct conditions with their own characteristics and treatment needs. Read more about this groundbreaking research in the detailed article from New Atlas: https://lnkd.in/ekx9UgP6 #AlzheimersResearch #MedicalInnovation #Neuroscience #Healthcare

🧠 Exciting Update from the Kioloa Neurosciences Colloquium! 🧠 I'm delighted to share insights from my recent talk at the Kioloa Neurosciences Colloquium, where I delved into the intricate neural mechanisms underlying pain in Multiple Sclerosis (MS) and Fibromyalgia. Our preliminary data from our longitudinal study at Western Sydney University shed fascinating light on this complex topic. Understanding pain in MS is crucial for improving the quality of life for patients, and our study is dedicated to achieving that. We're investigating the potential biomarkers reflecting pain in MS and Fibromyalgia patients over time, offering invaluable insights into potential treatments and interventions. But we can't do it alone! We're actively seeking participants to join our study. If you or someone you know is living with MS or an autoimmune disease and is interested in contributing to cutting-edge research that could make a real difference, we'd love to have you on board. Want to learn more about our study or get involved? 👉 Feel free to reach out to me directly or visit the MS Australia website https://bit.ly/3QNSwjN for more information. Let's pave the way for a better understanding and management of pain in Multiple Sclerosis! #MultipleSclerosis #MSResearch #Fibromyalgia #Neuroscience #PainMechanisms #KioloaNeurosciencesColloquium #PhD #WesternSydneyUniversity

Dear Colleagues, as Guest Editor of the Special Issue “Molecular Motors in Neuronal Homeostasis and Neurodegeneration,” I am pleased to invite you to contribute a research article or comprehensive review. This Special Issue aims to explore the crucial roles of molecular motors in neuronal development, cellular dynamics, in the mechanisms underlying neurodegenerative diseases, their involvement in potential novel therapies, among other interesting topics in molecular neurosciences. If you have any questions or need further information, please feel free to reach out. For more details, you can also check the official website of the Special Issue below. https://lnkd.in/dE4jv3Vg Brain Sciences MDPI

🌟 Unlocking the intricate genetics of Huntington's disease & related disorders goes beyond triplet repeats. Dive into the latest insights and breakthroughs in this complex field. #HuntingtonsDisease #Genetics #Research" Discover the latest research on Ageing and Neurodegenerative Diseases Journal! Delve into groundbreaking studies unraveling the mysteries of age-related brain disorders. Stay informed, stay ahead. #Neuroscience #Aging

🌟🧬 Dive into the world of #SingleCellGenomics and its impact on #Neurodevelopmental disorders like autism in our on-demand webinar from Scale Biosciences 🧠🧬 #Neuroscience #Genomics. On-demand now → https://buff.ly/3Hpqnur

🌟💬 Xtalks Spotlight: To learn why companies developing treatments for #Alzheimer’s disease should consider including EEG biomarkers in clinical studies, Xtalks spoke with Christopher (CJ) Barnum PhD, VP of CNS Development at INmune Bio Inc. and Brian Murphy, PhD, Co-Founder and Chief Scientific Officer of Cumulus Neuroscience. 🧠 Watch the full interview with Dr. Barnum and Dr. Murphy here: https://buff.ly/3VYUfX3 #CNSTrials #DigitalBiomarker #DigitalBiomarkers #XtalksSpotlight #NeuroscienceTrials #NeuroscienceClinicalTrials #CNSDrugDevelopment #AlzheimersDiseaseTrials #NeurodegenerativeDisease