JIM - Journal of Internal Medicine’s Post

The newest clinical study showing that PRP dose is critical to success continues to align with our almost two decade old experience from culturing MSCs. https://lnkd.in/gcuSyytJ

🔬Elevating Patient-Centric Care in Chronic Inflammatory Diseases (CIDs) 🌟   🩺 At Avenna, our mission revolves around supporting the prognosis, diagnosis, and treatment of Chronic Inflammatory Diseases (CIDs). We prioritise patient satisfaction and aim to simplify the adoption of testing methods for early detection and personalised treatment.   We are delighted to share our collaboration with Trajan Scientific and Medical in a pioneering research initiative. In partnership with Trajan, we are exploring Patient-Centric Microsampling using Trajan's Mitra® microsampling devices based on VAMS® technology.   🌐 The Goals: Test the Mitra Device as a new, patient-friendly blood microsampling method that is minimally invasive and easily performed in-house. Assess the method's capability to provide reliable information for N-glycan analysis and ensure the stability of blood samples during national and international shipping via standard mail.   📊 Trajan's Microsampling Research Support Program: This research is part of Trajan's Microsampling Research Support Program, demonstrating our shared commitment to advancing medical research.   🔍 What We're Looking For: Robustness and Stability of the sample: Ensuring the reliability of the microsampling method. User Feedback: Insights from both patients and technicians are invaluable to refining our approach. #PatientCentricCare #MicrosamplingResearch #InnovationInHealthcare #ChronicInflammatoryDiseases #GlyHealth #Glycans #CID #Inflammation #EarlyDetection #TreatmentPersonalisation #MitraDevices #Trajan  

PFA atrial fibrillation ablation, using the pentaspline PFA catheter (Farawave, Farapulse-Boston Scientific , is SAFE! The results of MANIFEST-17K study, recently published in Nature Medicine, are indeed very impressive. The co-authors should be congratulated for tediously pooling together retrospective real-world data from 106 centers in 20 countries regarding 17,642 treated patients. This is clearly the largest PFA study so far. We need however to wait cautiously for long-term clinical outcome in order to be convinced that we’re positively benefiting the patients. https://lnkd.in/dszec8yq

🚨 New Publication Alert: Breaking Boundaries: Exploring Recent Advances in Anticoagulation and Thrombosis Management! 🚨 Excited to announce our latest comprehensive review on the advances in anticoagulation and thrombosis management. This work dives deep into pivotal trials such as PACIFIC-AF and **RIVER, highlighting emerging anticoagulants and their role in shaping patient care. These innovations will improve outcomes, but they also emphasize the critical need for personalized care and vigilant patient monitoring. A special thanks to my incredible co-authors, Dr. Abdur Jamil, MD, Dr. Faryal Altaf, Dr. Siddiqui, and Dr. Shah, for their invaluable collaboration. Together, we continue to push the limits of what’s possible in medicine. 💪 📖 Read more here: https://lnkd.in/eNPKyrSs #Thrombosis #Anticoagulation #MedicalResearch #PatientCare #Collaboration

💡 Research News 💡   In June we published an interesting study entitled "Long-term outcomes after echocardiography versus fluoroscopy-guided left atrial appendage closure: Is there still a role for a simplified approach?" with David Niederseer as co-author.   📃 Left atrial appendage closure (LAAC) represents an alternative to oral anticoagulation for stroke prevention in patients with non-valvular atrial fibrillation (AF). While transoesophageal echocardiography is the current standard for guiding LAAC procedures, several centers have employed fluoroscopic guidance alone. However, data on long-term outcomes are lacking. In this study LAAC with fluoroscopy guidance alone is equally safe and leads to similar clinical outcome compared to LAAC with additional echocardiography guidance.   📌 Link to full text: https://lnkd.in/e6H_epRg     #ResearchHochgebirgsklinikDavos #davosscience #davosresearch #research #echocardiography #fluoroscopy   David Niederseer Jan Vontobel Thomas Gilhofer Victor Konstantin Schweiger Mi Chen, Alessandro Candreva, Davide Di Vece, Christian Templin, Barbara E. Stähli, Julia Stehli, Ronald K. Binder, Fabian Nietlispach, Prof. Dr. med. Markus Kasel, Frank Ruschitzka, Jonathan Michel, Michael Würdinger, Alexander Gotschy, Philipp Jakob, Medizincampus Davos Science City Davos Hochgebirgsklinik Davos

"Evidence-based medicine means applying real standards, looking at clinical studies critically, and deciding if a particular medication, treatment, or diagnostic study should be used broadly or have some unique standards." Aranscia's Dr. Joel Diamond, in a recent interview with Population Health Learning Network's Annals of Long-Term Care, discussed the current state of #precisionmedicine and how future advancements will continue to make major impacts in long-term and post-acute care. Read more here: https://lnkd.in/gECj8YgT #personalizedmedicine #pharmacogenomics #pgx #precisiononcology #behavioralhealth #longtermcare #postacutecare #DrJoelDiamond

The Power of Data in Medical Innovation The recent four-year study on Sotyktu (deucravacitinib) for moderate-to-severe plaque psoriasis showcases the transformative potential of comprehensive data analysis. Consistent safety and durable response rates underline its efficacy, highlighting the importance of long-term data in advancing treatment options. At CIMS, we leverage revolutionary tools to harness robust data, driving forward innovations that enhance patient care and outcomes. Let's continue to unlock the full potential of data for a healthier future. #DataDriven #MedicalInnovation #CIMS #HealthcareTransformation #clinicaltrials

𝗣𝗮𝘁𝗶𝗲𝗻𝘁 𝗖𝗵𝗿𝗼𝗻𝗼𝘁𝘆𝗽𝗲 𝗖𝗼𝘂𝗹𝗱 𝗜𝗺𝗽𝗮𝗰𝘁 𝗕𝗲𝘀𝘁 𝗧𝗶𝗺𝗲 𝘁𝗼 𝗧𝗮𝗸𝗲 𝗕𝗹𝗼𝗼𝗱 𝗣𝗿𝗲𝘀𝘀𝘂𝗿𝗲 𝗠𝗲𝗱𝗶𝗰𝗮𝘁𝗶𝗼𝗻 A new study showed that hypertention patients had a reduced risk of heartattack when taking their medicine aligned to their body clock. Chronotherapy matters to control blood pressure with antihypertension medication. This is a new finding of a study conducted by University’s School of Medicine of the University of Dundee, in collaboration with #HelmholtzMunich, and in partnership with an international team of researchers from Italy, UK and the USA - published in eClinicalMedicine. 👉 Learn more: https://lnkd.in/dsEx-FDH Kenneth Dyar Filippo Pigazzani #chronotherapy #hypertension #therapy #BodyClock #InnerClock #chronotype #heartattack #PersonalizedMedicine #circadianmedicine #SRBR2024 #cardiovasculardisease

🌟 Exciting Research Update! 🌟 I'm thrilled to share that our latest paper, "Clustering Analysis of HRCT Parameters Measured Using a Texture-Based Automated System: Relationship with Clinical Outcomes of IPF," has been published in BMC Pulmonary Medicine. Authors: Jong-Uk Lee, Jong-Sook Park, Eunjeong Seo, Jin Seol Kim, Hae Ung Lee, Yongjin Chang, Jai Seong Park, & Choon-Sik Park. In this study, we explored the potential of automated quantitative analysis of high-resolution CT (HRCT) parameters to predict clinical outcomes in patients with idiopathic pulmonary fibrosis (IPF). By analyzing HRCT images from 159 IPF patients using the AVIEW software from Coreline Soft, we identified key lung texture patterns such as honeycombing, reticulation, emphysema, consolidation, and ground glass opacity. Our cluster analysis revealed three distinct patient groups based on these parameters: 1️⃣ Cluster 1: Patients with the lowest parameter values, exhibiting the longest survival and well-preserved lung function, with a relatively high Forced Vital Capacity (FVC) and Diffusing Capacity of the Lungs for Carbon Monoxide (DLCO). 2️⃣ Cluster 2: Patients with high reticulation and consolidation scores, showing the lowest FVC and DLCO, and the shortest survival, predominantly affecting female patients. 3️⃣ Cluster 3: Male smokers with high honeycombing and emphysema scores, with intermediate survival rates and moderate FVC levels. This study underscores the effectiveness of automated quantitative CT analysis in predicting clinical outcomes in IPF and highlights the potential for identifying high-risk groups who may benefit from targeted management strategies. Check out the full paper here: https://lnkd.in/gMHQvNgf #IPF #PulmonaryMedicine #HRCT #MedicalImaging #QuantitativeAnalysis #Research #AVIEW #CorelineSoft

#ISMINIM2023 Wu Mingsong, Director/Chief Physician, Department of Oncology and Hematology, Beiliu People's Hospital, discussed on clinical practice in the minimally invasive and non-invasive treatment of hepatobiliary and pancreatic cancer guided by integrated medical sciences. Initial progress has been made in integrated medical sciences of hepatobiliary and pancreatic cancer, which deserves further exploration. Integrated medical sciences is an emerging medical system emphasizing on from “disease” to “patient”, embodying humanistic medicine. Minimally invasive intervention plus HIFU non-invasive ablation, as well as organic integration of other systemic treatments and conditioning, can benefit patients more. Watch the lecture: https://lnkd.in/gYg9d8My #livertumor #cancer #minimallyinvasive #noninvasive