Julia Popp’s Post

Will you be attending the 2023 Safety Pharmacology Society Annual Meeting in Brussels September 18-21? If so, don’t miss your chance to connect with Labcorp about the latest in Pharmacology innovation. We will have a team onsite and would be happy to schedule a meeting to talk about your project needs. Also check out the7 Labcorp posters on display: 1. Validation of an ICH E14/S7B Q&A Best Practice Compliant hERG Assay (#051) 2. Multi-site Validation of in vivo QT ICH E14/S7B Q&A Guidance in Canines and Non-Human Primates (#015) 3. Assessment of Moxifloxacin-induced QTc Prolongation in Canine and Nonhuman Primate Using a Linear Mixed Effect Modeling Approach (#017) 4. Evaluation of the Head Twitch Response in Male C5BL/6 Mice as a Measure of 5-HT2a Receptor Activation (#029) 5. An Investigation into the Relationship between Acetazolamide Systemic Exposure, Blood Gas Changes and Ventilatory Parameters in the Sprague Dawley Rat (#124) 6. Evaluating the Cardiovascular Effects of Lipid Nanoparticle-Encapsulating mRNA Therapeutics in Cynomolgus Monkeys Using Telemetry and Star-Oddi Logger Devices (#133) 7. Cardiovascular Assessment of Lipid Nanoparticle-Encapsulating mRNA Therapeutics in Rats using Telemetry and Star-Oddi Logger Devices (#135) And we are privileged to be a part of 5 industry working group collaborative posters: 1. Heart Rate Corrected JTp and Tpe as Proarrhythmia Biomarkers in Safety Pharmacology Non-Human Primate Studies: Outcome from a HESI Consortium Prospective Study (#025) 2. Towards Best Practices: A Cross-Company Survey of Nonclinical C-QT Analysis in Drug Development (#023) 3. Best Practice Considerations for Nonclinical In Vivo Cardiovascular Telemetry Studies with Alternative Study Designs in Non-Rodent Species (#013) 4. An Evaluation of Drug-Induced Blood Pressure Changes in a Standard Canine CV Safety Pharmacology Study: a HESI-sponsored Consortium (#026) 5. Recommendations on the Measurement of Electrocardiogram and Hemodynamic Parameters in Restrained Non-rodent Species in Regulatory Safety Assessment Studies (#007)