LCGC Chromatography Solutions ’s Post

Agilent InfinityLab Quick Change Inline Filter for HPLC. . Particles can come from everywhere in the flow path - solvents, samples or worn instrument parts. Over time, particles clog the column frit, causing pressure increases and shorter column lifetime. The Agilent InfinityLab Quick Change HPLC inline filter protects valuable columns by capturing particles before they reach the column, extending their use and reducing your cost per sample. The innovative Quick Change HPLC inline filter enables finger-tight, tool-free replacement of HPLC filter discs. A click sound tells you when your inline solvent filter is tight up to 1300 bar, with no risk of over- or under-tightening. The filter housing is robust for over 100 replacements to reduce operation cost and avoid troubleshooting. Five different dimensions and porosities of HPLC filter discs are available to suit all your needs. Features. Efficient filtration of particles to protect columns and extend column lifetime Tool-free Click and seal - a click sound tells you when the filter is tight up to 1300 bar In-situ replacement of HPLC filter disc without disconnecting the filter from flow path Robust filter housing for over 100 HPLC filter disc replacements to lower operational costs Five types of HPLC filter discs available - 2.1mm id with 0.2µm/0.5µm pore size, 4.6mm id with 0.2µm/0.5µm/2.0µm pore size Touchless packaging enables no-touch insertion of HPLC filter disc into filter housing . . . . #lcgc #chromatography #chrome #pharmaceutical #pharma #pharmacy #linkedin #network #post #social #linkbuilding #linkedinconnections #linkedin #linkedingrowth #agilent #column #hplc #linkedincommunity #growthmindseth #marketingstrategy

InfinityLab Quick Change Inline Filter for HPLC . . . Particles can come from everywhere in the flow path - solvents, samples or worn instrument parts. Over time, particles clog the column frit, causing pressure increases and shorter column lifetime. The Agilent InfinityLab Quick Change HPLC inline filter protects valuable columns by capturing particles before they reach the column, extending their use and reducing your cost per sample. The innovative Quick Change HPLC inline filter enables finger-tight, tool-free replacement of HPLC filter discs. A click sound tells you when your inline solvent filter is tight up to 1300 bar, with no risk of over- or under-tightening. The filter housing is robust for over 100 replacements to reduce operation cost and avoid troubleshooting. Five different dimensions and porosities of HPLC filter discs are available to suit all your needs. Features Efficient filtration of particles to protect columns and extend column lifetime Tool-free Click and seal - a click sound tells you when the filter is tight up to 1300 bar In-situ replacement of HPLC filter disc without disconnecting the filter from flow path Robust filter housing for over 100 HPLC filter disc replacements to lower operational costs Five types of HPLC filter discs available - 2.1mm id with 0.2µm/0.5µm pore size, 4.6mm id with 0.2µm/0.5µm/2.0µm pore size Touchless packaging enables no-touch insertion of HPLC filter disc into filter housing . . . . #lcgc #chromatography #chrome #pharmaceutical #pharma #pharmacy #linkedin #network #post #social #linkbuilding #linkedinconnections #linkedin #linkedingrowth #agilent #column #hplc #linkedincommunity #growth #marketingstrategy

InfinityLab Quick Change Inline Filter for HPLC . . . Particles can come from everywhere in the flow path - solvents, samples or worn instrument parts. Over time, particles clog the column frit, causing pressure increases and shorter column lifetime. The Agilent InfinityLab Quick Change HPLC inline filter protects valuable columns by capturing particles before they reach the column, extending their use and reducing your cost per sample. The innovative Quick Change HPLC inline filter enables finger-tight, tool-free replacement of HPLC filter discs. A click sound tells you when your inline solvent filter is tight up to 1300 bar, with no risk of over- or under-tightening. The filter housing is robust for over 100 replacements to reduce operation cost and avoid troubleshooting. Five different dimensions and porosities of HPLC filter discs are available to suit all your needs. Features Efficient filtration of particles to protect columns and extend column lifetime Tool-free Click and seal - a click sound tells you when the filter is tight up to 1300 bar In-situ replacement of HPLC filter disc without disconnecting the filter from flow path Robust filter housing for over 100 HPLC filter disc replacements to lower operational costs Five types of HPLC filter discs available - 2.1mm id with 0.2µm/0.5µm pore size, 4.6mm id with 0.2µm/0.5µm/2.0µm pore size Touchless packaging enables no-touch insertion of HPLC filter disc into filter housing . . . . #lcgc #chromatography #chrome #pharmaceutical #pharma #pharmacy #linkedin #network #post #social #linkbuilding #linkedinconnections #linkedin #linkedingrowth #agilent #column #hplc #linkedincommunity #growth #marketingstrategy

InfinityLab Quick Change Inline Filter for HPLC Particles can come from everywhere in the flow path - solvents, samples or worn instrument parts. Over time, particles clog the column frit, causing pressure increases and shorter column lifetime. The Agilent InfinityLab Quick Change HPLC inline filter protects valuable columns by capturing particles before they reach the column, extending their use and reducing your cost per sample. The innovative Quick Change HPLC inline filter enables finger-tight, tool-free replacement of HPLC filter discs. A click sound tells you when your inline solvent filter is tight up to 1300 bar, with no risk of over- or under-tightening. The filter housing is robust for over 100 replacements to reduce operation cost and avoid troubleshooting. Five different dimensions and porosities of HPLC filter discs are available to suit all your needs. Features Efficient filtration of particles to protect columns and extend column lifetime Tool-free Click and seal - a click sound tells you when the filter is tight up to 1300 bar In-situ replacement of HPLC filter disc without disconnecting the filter from flow path Robust filter housing for over 100 HPLC filter disc replacements to lower operational costs Five types of HPLC filter discs available - 2.1mm id with 0.2µm/0.5µm pore size, 4.6mm id with 0.2µm/0.5µm/2.0µm pore size Touchless packaging enables no-touch insertion of HPLC filter disc into filter housing #lcgc #chromatography #chrome #pharmaceutical #pharma #pharmacy #linkedin #network #post #social #linkbuilding #linkedinconnections #linkedin #linkedingrowth #agilent #column #hplc #linkedincommunity #growth #marketingstrategy

Flushing an HPLC (High-Performance Liquid Chromatography) system is crucial for maintaining column performance and preventing issues. Let's explore the importance of using hot water for flushing and how it impacts the system: 1. Pressure Issues and Column Contamination: - High back pressure in an HPLC system can be caused by various factors, including column contamination, plugged inlet frits, or blockages elsewhere in the system. - Flushing the column with hot water helps eliminate contaminants, such as high molecular weight compounds or adsorbed substances, which may accumulate over time. - Procedure: - Rinse the column (remove the detector from the flow path) to eliminate contamination and plugged packing. - Back flush the column to clear any blockages in the inlet frit. - Consider changing the column inlet frit if necessary. - Adding a disposable 0.5 μm or 2 μm in-line filter to the system can prevent pressure issues. 2. Baseline Noise and Flow Cell Flushing: - Baseline noise in UV detectors (such as diode array detectors) can be caused by a dirty flow cell. - Flushing the flow cell helps remove contaminants and improve baseline stability. - Procedure: - Disconnect the column and place a union instead. - Reverse the cell flow path by swapping the inlet and outlet lines. - Flush the flow cell with HPLC-quality water at 5 mL/min for 5 minutes. - Then, flush with 100% isopropanol (IPA) for at least 1 hour. - Swap the inlet and outlet lines back to their original positions and check if the baseline issue disappears. 3. Prevent Precipitation and Drying: - Flush the system with water to prevent precipitation of mobile phase buffers within the column's sorbent bed. - Seal the column with end plugs to prevent drying of the chromatographic bed. Remember that proper maintenance, including regular flushing, ensures optimal HPLC performance and extends the column's lifetime. If you encounter persistent issues. #pharmaceutical #HPLC #Method #ICH #Inspire #Columns #Chromatography

*🚀Choosing the Right Syringe Filter: 0.45 µm vs. 0.22 µm – Key Differences* Selecting the appropriate syringe filter is crucial for achieving accurate and reliable results in lab processes. The two common pore sizes, *0.45 µm* and *0.22 µm*, serve different purposes: - *0.45 µm Filter: Ideal for **general filtration* and removing large particulates, commonly used in *clarifying samples* like buffers, solvents, or media where fine sterilization isn't required.    - *0.22 µm Filter: Best suited for **sterilizing filtration, effectively removing **bacteria and smaller particles, making it essential for **biological samples* and sensitive applications. *Which to choose?*   - For *non-sterile applications* like HPLC sample prep, go with *0.45 µm*. - For *sterile filtration* or when handling *microorganism-sensitive samples, the **0.22 µm* filter is your go-to. Selecting the right pore size can streamline your workflow and improve the accuracy of your experiments. #Laboratory #Filtration #Pharma #HPLC #SyringeFilters #Biotech #Research #SterileFiltration 

🚀Present Value with Customer Long-Term Benefit in Mind and not Slashing Price for Short-Term Benefit: HPLC as example🚀 Achieve Unmatched Gradient Performance with XXX HPLC System In today’s fast-paced labs, consistency and precision are key. The XXX HPLC system stands out for its superior gradient performance, enabling seamless method transfer from different brand HPLCs while maintaining high accuracy. 1. Feature (F): The XXX HPLC is built with a torpedo pump design featuring active pulse damping, stroke volume optimization and a fixed delay volume. This cutting-edge technology provides precise and consistent flow rates, ensuring the formation of reproducible gradients with every run. 2. Advantage (A): This pre-compressed make-up pressure during pump stroke transitions eliminates any dips in pressure, ensuring smoother solvent delivery and reducing noise in chromatographic baselines. This system synchronizes injection timing with the formation of the gradient, leading to enhanced reproducibility and method transferability across different HPLC brands. 3. Benefit (B): For labs seeking to transfer methods from other HPLC systems, the XXX HPLC ensures seamless transition with minimal revalidation time. Its pre-compressed make-up pressure technology and active pulse damping enhance reproducibility, allowing you to meet regulatory requirements faster, avoid unnecessary troubleshooting, and maintain high throughput. 4. Evidence (E): The XXX HPLC has been widely adopted in both QC and research environments globally, praised for its reliable performance across multiple industries. It’s been proven to reduce downtime and enhance lab productivity. Numerous case studies from pharmaceutical companies demonstrate improved compliance and faster method validation using the XXX HPLC. This system not only enhances your current operational efficiency but future-proofs your lab for smooth method transfers and higher precision. Imagine reducing your troubleshooting time and meeting compliance with ease—what would that mean for your lab? Addressing the "Too Expensive" Comment While it may seem like a premium investment upfront, the long-term benefits far outweigh the cost. Not only does the xxx HPLC minimize errors and optimize method transfers, but it also reduces operational costs associated with wasted materials and re-analysis. Over time, these savings can significantly exceed any initial investment. Our customers frequently report enhanced lab productivity, citing faster, more accurate results upon integration. By choosing the XXX HPLC, you’re also choosing consistent quality—a critical factor for regulatory compliance and long-term profitability. #HPLC #LabEfficiency #Chromatography #PrecisionScience Please feel free to comment and connect Gordon Tai 戴国栋, MBA I am a member of the #LBFalumni & #SkyHighTower #GORDONᴛAi #GORDONᴛAiOnSTRAtegy #GORDONᴛAiOnSALES

HPLC Solvent Inlet Filters. HPLC solvent inlet filters represent the first barrier for retaining particles, precipitates, and microbes from mobile phases, buffers, and salt solutions at HPLC inlet. Agilent provides a wide range of high-quality glass and stainless steel HPLC inlet filters with different pore sizes. Further down the flow path, Agilent inline filters can be installed at the high-pressure side to filtrate even smaller particles from solvents, samples and system worn parts. Both Agilent solvent inlet filters and inline filters are designed for and tested on Agilent instruments to ensure best fit and protection of your valuable columns against particle clogging. These inlet solvent filters are critical for preventing pressure increases and contamination, leading to extended column lifetime, increased analytical efficiency and decreased cost per sample. The new Quick Change inline filter with finger-tight filter disc replacement provides ultimate ease of use and robustness. Features Agilent solvent inlet filters have a defined, homogeneous pore size to effectively block particles above a certain size, while letting the mobile phase through without a significant pressure increase Agilent solvent inline filters can be installed before column to capture particles from solvents, samples and system worn parts to protect columns, extending column lifetime InfinityLab Quick Change inline filters are innovatively designed to enable finger-tight filter disc replacement, with click & seal to avoid over- or undertightening and superior robustness for lower operational costs #lcgc #chromatography #chrome #pharmaceutical #pharma #pharmacy #linkedin #network #post #social #linkbuilding #linkedinconnections #linkedin #linkedingrowth #agilent #column #hplc #linkedincommunity #growthmindseth #marketingstrategy

HPLC Solvent Inlet Filters. HPLC solvent inlet filters represent the first barrier for retaining particles, precipitates, and microbes from mobile phases, buffers, and salt solutions at HPLC inlet. Agilent provides a wide range of high-quality glass and stainless steel HPLC inlet filters with different pore sizes. Further down the flow path, Agilent inline filters can be installed at the high-pressure side to filtrate even smaller particles from solvents, samples and system worn parts. Both Agilent solvent inlet filters and inline filters are designed for and tested on Agilent instruments to ensure best fit and protection of your valuable columns against particle clogging. These inlet solvent filters are critical for preventing pressure increases and contamination, leading to extended column lifetime, increased analytical efficiency and decreased cost per sample. The new Quick Change inline filter with finger-tight filter disc replacement provides ultimate ease of use and robustness. Features Agilent solvent inlet filters have a defined, homogeneous pore size to effectively block particles above a certain size, while letting the mobile phase through without a significant pressure increase Agilent solvent inline filters can be installed before column to capture particles from solvents, samples and system worn parts to protect columns, extending column lifetime InfinityLab Quick Change inline filters are innovatively designed to enable finger-tight filter disc replacement, with click & seal to avoid over- or undertightening and superior robustness for lower operational costs #lcgc #chromatography #chrome #pharmaceutical #pharma #pharmacy #linkedin #network #post #social #linkbuilding #linkedinconnections #linkedin #linkedingrowth #agilent #column #hplc #linkedincommunity #growthmindseth #marketingstrategy

HPLC Solvent Inlet Filters HPLC solvent inlet filters represent the first barrier for retaining particles, precipitates, and microbes from mobile phases, buffers, and salt solutions at HPLC inlet. Agilent provides a wide range of high-quality glass and stainless steel HPLC inlet filters with different pore sizes. Further down the flow path, Agilent inline filters can be installed at the high-pressure side to filtrate even smaller particles from solvents, samples and system worn parts. Both Agilent solvent inlet filters and inline filters are designed for and tested on Agilent instruments to ensure best fit and protection of your valuable columns against particle clogging. These inlet solvent filters are critical for preventing pressure increases and contamination, leading to extended column lifetime, increased analytical efficiency and decreased cost per sample. The new Quick Change inline filter with finger-tight filter disc replacement provides ultimate ease of use and robustness. Features Agilent solvent inlet filters have a defined, homogeneous pore size to effectively block particles above a certain size, while letting the mobile phase through without a significant pressure increase Agilent solvent inline filters can be installed before column to capture particles from solvents, samples and system worn parts to protect columns, extending column lifetime InfinityLab Quick Change inline filters are innovatively designed to enable finger-tight filter disc replacement, with click & seal to avoid over- or undertightening and superior robustness for lower operational costs . . . #lcgc #chromatography #chrome #pharmaceutical #pharma #pharmacy #linkedin #network #post #social #linkbuilding #linkedinconnections #linkedin #linkedingrowth #agilent #column #hplc #linkedincommunity #growth #marketingstrategy