Linda Lowes’ Post

My calling: Find a cure for Alzheimer's. Many of you asked me about my professional endeavors since departing Philips. My focus has been exploring causes and treatments for Alzheimer's disease, delving into endless studies and clinical trials—originally not for business purposes but due to a deeply personal connection. The painful experience of watching my grandparents, uncle, and aunt deteriorate has been incredibly challenging. Now I'm facing it once more, this time much closer to home. It quickly became apparent to me that there were no available treatments for Alzheimer’s disease, nor were there any promising options emerging. Not because neuroscientists do not try hard enough. They do. Very hard. However, what I found was that if you start developing a treatment based on a medical fallacy, all possible outcomes are destined to fail. In the last 20 years alone, approximately 2,700 phase II and III clinical trials failed. Astounding >99% failure. Which medical fallacy am I referring to? Well, it appears that all studies (literally) related to the brain's waste elimination process, known as the glymphatic system, have been and continue to be performed using MRI or PET scans with the subject lying down at rest. And that’s the problem. For decades, it was believed that the brain’s waste removal processes were constant, regardless of rest, sleep, or physical activity. That is simply not true. We have evolved around motion, and brain waste removal is affected by physical activity. Over the coming weeks, I will be publishing my medical hypothesis, what we discovered, and how we measured it. Given my conviction that science ought to be accessible to everyone, I will do this in the form of several (not so) short medical video animations. And this is the first part. Today’s understanding of CSF and waste removal. Please comment with your questions or critique and repost my videos in your network. I’m very certain that questioning today’s understanding of Alzheimer’s disease will help us find the cure. Enjoy. #EndAlz #MotoGlymphatic #Glymphatic

Breakthrough spinal patch uses natural body motion to repair herniated discs https://flip.it/6MmOji

Extraordinary education in musculoskeletal diagnostics: 50th annual meeting of the International Skeletal Society in September 2024. Easy to reach, interesting city. @intskeletalsociety https://lnkd.in/dGhj27Wu

🐀🫀Today’s shared video showcases the meticulous dissection of a rat heart's left ventricle and isolation of papillary muscles. Papillary muscle allows measurements too difficult or impossible to perform in whole hearts. Similarly, unlike single isolated myocytes, which represent the smallest fully functional model system, intact papillary muscle can be used to study cardiac function within a multicellular context and an intact 3-dimensional myofilament lattice. Check out our video tutorial that demonstrates the dissection of the rat heart's left ventricle and the removal of the papillary muscles. *** Wanna learn more? Explore these systems related to the linked video - our NEW Cardiac Slice System and Intact Muscle Chamber System! https://lnkd.in/et9ndNGk https://lnkd.in/eQ6y-QC3

I am excited to contribute with an article focusing on the assessment of cardiac muscle function utilizing NILES2024.

Hamstring injuries are common in elite sports. Muscle injury classification systems aim to provide a framework for diagnosis. The British Athletics Muscle Injury Classification (BAMIC) describes an MRI classification system with clearly defined, anatomically focused classes based on the site of injury: (a) myofascial, (b) muscle-tendon junction or (c) intratendinous; and the extent of the injury, graded from 0 to 4. However, there are no clinical guidelines that link the specific diagnosis (as above) with a focused rehabilitation plan.

EMGs: Your roadmap to relief from back and neck discomfort. 🏆 Let the power of electromyography guide you towards targeted treatments and a life without pain at Spine Team Texas. Say hello to a happier, healthier spine with Dr. Donnelly-Straach!

Becker Education and Engagement Day is this Saturday! If you were not able to attend last year's BEED, it's not too late to gain valuable insights from Dr. Vandenborne's 2023 presentation: "Imaging Muscles in Becker Muscular Dystrophy." Learn more about how measuring muscle fat fraction helps inform clinical trials: https://lnkd.in/eRGVxswg #BeckerMuscularDystrophy

Whether you're working to improve athletic performance or the diagnosis of gait disorders, you need the right information. Learn how gait analysis can help your biomechanical research in today’s blog. https://hubs.li/Q02Ks0Xy0

Brain injury (BI) awareness is growing, but many still struggle to understand how to recognize it and support those affected. 🌱 Join us on October 22nd for the Brain Injury Networking event with Harry White from Be Physiology, who will share key strategies for helping people reconnect with their communities during recovery. Let's make a difference together! ✨ #BrainInjuryAwareness #CommunitySupport #SynapseAustralia Don't miss it! 😊 #BrainInjuryAwareness #Networking #Rehabilitation #CommunitySupport #SynapseAustralia