Loubna Youssar’s Post

Scientists have made an interesting discovery! A bacterial version of reverse transcriptase can read RNA and create new genes in DNA. This new genetic material is then transcribed back into RNA, which helps produce protective proteins when a bacterium is infected by a virus. This process is different from viral reverse transcriptases, which only transfer information from RNA to DNA. Check out the article to learn more about this fascinating finding! #science #genetics #research https://lnkd.in/erBtEsSr

Crazy molecular biology - A bacterial version of reverse transcriptase reads RNA as a template to make completely new genes written in DNA. These genes are then transcribed back into RNA, which is translated into protective proteins when a bacterium is infected by a virus. By contrast, viral reverse transcriptases don’t make new genes; they merely transfer information from RNA to DNA.

Sequencing and characterizing short tandem repeats in the human genome

The use of long-read sequencing technology, in combination with the recently completed telomere-to-telomere human reference genome (T2T-chm13), enables us to explore uncharted Aboriginal genomic variation. Long reads can resolve repetitive or non-unique genes and regions that are intractable with dominant short-read sequencing platforms. Long reads are also superior for the detection of structural variants (SVs), which account for the majority of the differences between the genomes of any 2 individuals and at least 25% of their deleterious alleles, yet are poorly understood owing to technical and analytical limitations. https://lnkd.in/etYnufAJ

Introns are perhaps one of our genome's biggest mysteries. They are DNA sequences that interrupt the sensible protein-coding information in our genes, and need to be "spliced out." The human genome has hundreds of thousands of introns, about 7 or 8 per gene, and each is removed by a specialized RNA protein complex called the "spliceosome" that cuts out all the introns and splices together the remaining coding sequences, called exons. How this system of broken genes and the spliceosome evolved in our genomes is not known. https://lnkd.in/gTekw-79

Are you a student, or a newbie in DNA sequencing? Want to learn how whole genome sequencing works? Check out this article: #sequencing #DNAsequencing #genomesequencing #NGS

Whole Genome Sequencing CD Genomics has been providing the accurate and affordable whole genome sequencing service for couple of years. We combine both Illumina (short reads) and PacBio (long reads) platforms to achieve whole genome de novo assemblies and re-sequencing for viruses, microbes, plants, animals and humans. For more information: https://lnkd.in/eiAHQj49 #genetics #biology #ngs #epigenetics

Research Spotlight: Programmable Genome Writing Via Click Editing with DNA Polymerases and HUH Endonucleases https://lnkd.in/e3ByK2p5

New gene-editing tool found in bacterium could carry out extensive genome remodelling: Highly selective mechanism can insert, remove and flip large portions of DNA https://buff.ly/3zv2W23 #geneediting

The human genome, an intricate tapestry of genetic information for life, has proven to be a treasure trove of strange features. Among them are segments of DNA that can "jump around" and move within the genome, known as "transposable elements" (TEs). As they change their position within the genome, TEs can potentially cause mutations and alter the cell's genetic profile, but also are master orchestrators of our genome's organization and expression. For example, TEs contribute to regulatory elements, transcription factor binding sites, and the creation of chimeric transcripts—genetic sequences created when segments from two different genes or parts of the genome join together to form a new, hybrid RNA molecule.