Lunaphore (a Bio-Techne brand)’s Post

🌟 Expedite Your #DrugDiscovery With Our Targeted #InVitro #BiochemicalAssays.  💡 Gain Deeper Insights Into Your Novel Modalities’ #MOA, #Pharmacodynamics, Or #Potency 🧫 Explore Our Comprehensive Assay Library, Including #ReceptorBinding, #OxidativeStress, #DNADamage, And More 🔬 Utilize Precise Multi-Platform Detection: #Fluorescence, TR-FRET (#HTRF), BRET, #AlphaLISA, Or Colorimetric Assays 🤝 Collaborate With Seasoned Scientists To Tailor Your Assay Strategy And Propel Your #TherapeuticResearch 👩🔬Take The First Step, Speak To Our Scientist Today. https://lnkd.in/dw2ra3KM

Experience enhanced efficiency in HSC differentiation with Cultrex™ BME compared to the leading competitor’s matrix. Elevate your experiments by using a matrix that delivers optimal results. #Research #DrugDiscovery #RegenerativeMedicine #StemCells

#callforreading #recommendations #tittlestory in Methods and Protocols MDPI Title: Quantifying mRNA in Highly Degraded Fixed Tissues by Nanostring Technology: A Comparative Study Authors: Eros Azzalini, Barbara Di Stefano, Vincenzo Canzonieri, Tiziana Venesio, Umberto Miglio, Caterina Marchiò, Anna Sapino, Carlo Previdere, Paolo Fattorini and Serena Bonin are from Università degli Studi di Trieste, University of Turin and Università di Pavia Read and Download for #free at: https://lnkd.in/gmcFJJuE #methods #protocols #mRNA #nanostring #qPCR #tissues #molecularanalysis #geneexpression #nucleicacids #DNA

Published in November 2023 via MDPI, the continual struggle against the ravages of sepsis has a new paper with a possible biomarker. One of the in-depth aspects of the experiment were investigating the effects of LPS on filamentous actin arrangement and apoptotic cell death. Actin filaments were observed via Phalloidin-iFluor® 555 reagent staining. To read the full text paper, click through here: https://lnkd.in/g3kxKrCY #citation #biotech #sepsis

New paper alert! Congratulations to Haguy Wolfenson and Lidan Shi on this great work! It was great collaborating to support your findings with some theoretical models, excellent work done by Hamidreza Jafarinia at MERLN Institute for Technology-Inspired Regenerative Medicine! https://lnkd.in/eAqpDXsT Highlights: • pYAP-Y357 accumulates at small adhesions on soft matrices and leads to apoptosis • YAP phosphorylation by c-Abl and Src drives the apoptotic decision • Failure of adhesion reinforcement determines pYAP-Y357 accumulation • Cellular decisions to undergo apoptosis or grow can be switched by myosin inhibition

“What is the biggest advantage of the new MolBoolean™ method? It provides the ability to simultaneously monitor both the levels of free proteins and their interactions in fixed cells and tissue.” Professor Ola Söderberg, Inventor of the MolBoolean Technology “The MolBoolean method was designed to incorporate targeting of both free and interacting proteins with one unified approach, instead of relying on orthogonal methods, keeping the efficiency in their reporting more similar." Read full testimonial on Atlas Antibodies website: https://ow.ly/z4tX50Stzzy #atlasantibodies #molboolean #proteinproteininteraction #insituPLA #primaryantibodies #humantissuestaining

It's MPX Monday and we are excited to release an important part of our CEO Simon Fredriksson's seminar on our Molecular Pixelation (MPX) technology. He talks about the three most important metrics obtained using MPX technology - ✅ Abundance of protein ✅ Spatial distribution of a single protein - Polarity Score ✅ Colocalization of proteins For a complete video, check out this link 👉 https://lnkd.in/dFxrmwrW #MPXMonday #molecularpixelation #MPX #abundance #proteins #spatialbiology #polarityscore #spatialbiology #cellsurface #surfaceproteins #CDmarkers #immunemarkers #Tcells #CD3 #cancercell #NKcell #surfaceproteome #CARTcells #colocalization #uropod #dataanalysis #endothelial #Bcell #cancercell #drugdevelopment

Happy #FluorescenceFriday! This FISH image shows the precise localization of a green fluorescent probe to the centromere regions of mouse chromosomes in both an interphase and a metaphase cell. This technology demonstrates the power of FISH (Fluorescence In Situ Hybridization) for detailed aneuploidy detection. The specificity of this probe is critical for projects that require clear delineation of centromeric regions, where it can be used alongside probes labeled with different fluorophores, either as a control probe or for aneuploidy detection. FISH testing can be used for aneuploidy detection in both mouse and human models. The utility of dual-species hybridization techniques ranges from comparative genomic studies to the identification of chromosomal anomalies. WiCell offers both cGMP and non-cGMP FISH analysis. Our FISH capabilities are just one part of the cytogenetic services we offer to assist in the pursuit of scientific understanding and innovation. Read more about all of our cytogenetic services at https://hubs.la/Q02h2Cm50

Biodesix scientist, Dylan Flohrschutz, will present their research on "Improved Patient Satisfaction with Capillary Blood Collection Devices as an Alternative to Venipuncture for Applications in Clinical Proteomic Assays" at the Association for Diagnostics & Laboratory Medicine 2024. Join the presentation at 1:30 p.m. Central Time on July 31st in the Poster Hall to learn more. Gary Pestano https://lnkd.in/gaErY7th #biodesix #diagnostics #lifesciences #proteomics

𝐒𝐮𝐩𝐞𝐫 𝐒𝐞𝐧𝐬𝐢𝐭𝐢𝐯𝐞 𝐈𝐇𝐂 𝐃𝐞𝐭𝐞𝐜𝐭𝐢𝐨𝐧 𝐒𝐲𝐬𝐭𝐞𝐦 𝐟𝐨𝐫 𝐂𝐥𝐞𝐚𝐧, 𝐂𝐫𝐢𝐬𝐩, 𝐈𝐧𝐭𝐞𝐧𝐬𝐞 𝐒𝐭𝐚𝐢𝐧𝐬 #BioGenex presents Super Sensitive™ Polymer-HRP #DetectionSystem - a breakthrough in #immunohistochemistry (IHC) technology. Our state-of-the-art system provides not only unmatched sensitivity but also produces clear, crisp, intense stains. 𝐅𝐞𝐚𝐭𝐮𝐫𝐞𝐬 𝐚𝐧𝐝 𝐁𝐞𝐧𝐞𝐟𝐢𝐭𝐬: ✦Fast 40 minutes turn-around time ✦Excellent sensitivity for low-abundant markers ✦Universal kit for rabbit and mouse antibodies ✦Higher dilution for most antibodies for reduced cost 𝐋𝐞𝐚𝐫𝐧 𝐌𝐨𝐫𝐞: https://hubs.la/Q02nwDbJ0