New research from MD Anderson includes identification of an enzyme that can be targeted as part of therapy that disrupts gastric cancer progression, as well as a biomarker that can stratify patients with neuroendocrine carcinoma. Read about these studies and more. #CancerResearch #EndCancer
MD Anderson Cancer Center’s Post
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Unlocking new treatment avenues for aggressive kidney cancer: The role of the HILPDA protein. https://lnkd.in/dABXDynM . . . . #KidneyCancer #CancerResearch #PrecisionMedicine #Biomarker #TherapeuticTarget #HILPDA #ScientificBreakthrough #PersonalizedMedicine #CancerTreatment #PatientOutcomes #ResearchInnovation #ClinicalTranslation #HopeForPatients #MedicalScience #PrecisionOncology
Unlocking New Treatment Avenues: The HILPDA Protein in Aggressive Kidney Cancer
meftii.com
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Chief Commercial Officer at NeoGenomics: Business & Commercial Execution – M&A integration – Turnarounds – Digital Transformation
Biomarker testing is an ever-evolving landscape. It's a topic discussed by a physician in this article: https://lnkd.in/epy6iUF7. He examines how it impacts treatment decisions for patients with early-stage non–small cell lung cancer (NSCLC), allowing for targeted approaches to be used earlier and more aggressively. #LungCancer #NSCLC #BiomarkerTesting . . . https://lnkd.in/epy6iUF7
Biomarker Testing Paves the Way for Better Targeted Therapies in NSCLC
targetedonc.com
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Identification of plasma exosomal lncRNA as a biomarker for early diagnosis of gastric cancer Frontiers https://lnkd.in/gwiqknmg
Frontiers | Identification of plasma exosomal lncRNA as a biomarker for early diagnosis of gastric cancer
frontiersin.org
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🔬 Dive into the intricate world of pancreatic cancer research with our latest Medium article! Discover how biomarkers are revolutionizing early detection, treatment, and prognosis. Read more: 👇 https://lnkd.in/d9MmiiET #PancreaticCancer #Biomarkers #PrecisionMedicine
The Science Behind MyHealthVerse — Deciphering the Puzzle: The Vital Link Between Biomarkers and…
medium.com
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Biologist @ National Institutes of Health (NIH) | PhD in Biomedical Sciences | Cancer Cell Biology | Tumor Biology | Neurodegenerative diseases
• Manuka honey enhances 5-FU-induced oxidative stress in colon cancer cells. • Manuka honey enhances 5-FU-induced apoptosis, regulating intrinsic and extrinsic pathway. • Manuka honey and 5-FU combination affects mitochondrial respiration and glycolysis. • Manuka honey enhances 5-FU-induced anti-metastatic effects, controlling MMP-2, MMP-9, and EMT markers expression.
Manuka honey synergistically enhances the chemopreventive effect of 5-fluorouracil on human colon cancer cells by inducing oxidative stress and apoptosis, altering metabolic phenotypes and suppressing metastasis ability
sciencedirect.com
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All things DUBs | Business Developer @ Ubiquigent | Biochemistry / Neuroscience PhD | 20+ years in life sciences industry biotech & CROs | SPR & Biacore Enthusiast | Volunteer Chair of Governors at local primary school.
Nice work by the Molecure team et al., validating the deubiquitinase, #USP21, as a potential target in cancer. Several biotech & pharma currently chasing this DUB target... #oncology #DUBinhibitor #cancerresearch #drugdiscovery
USP21 controls STAT3 activity and mitochondrial function of cancer cells justifying development of USP21 inhibitors. #mitochondria #drugdevelopment #deubiquitinase #cancer #STAT3 #cancermetabolism #cancertherapy #bioenergy #ATPproduction
The ubiquitin-specific protease 21 is critical for cancer cell mitochondrial function and regulates proliferation and migration
jbc.org
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In-house biomarker testing helped overcome barriers to care among patients diagnosed with metastatic non–small cell lung cancer (mNSCLC), particularly regarding individualized treatment decision, by shortening the period from diagnosis to treatment decision, according to findings recently published in Cancer Medicine: https://hubs.ly/Q02lxvh50 #biomarkertesting #NSCLC #cancer #lungcancer #TimeToTreatment #genomics4all
Referred molecular testing as a barrier to optimal treatment decision making in metastatic non‐small cell lung cancer: Experience at a tertiary academic institution in Canada
onlinelibrary.wiley.com
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USP21 controls STAT3 activity and mitochondrial function of cancer cells justifying development of USP21 inhibitors. #mitochondria #drugdevelopment #deubiquitinase #cancer #STAT3 #cancermetabolism #cancertherapy #bioenergy #ATPproduction
The ubiquitin-specific protease 21 is critical for cancer cell mitochondrial function and regulates proliferation and migration
jbc.org
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Comprehensive multi-level expression profiling of key biomarkers in breast cancer patients. https://lnkd.in/dSV9n4ZK
Comprehensive multi-level expression profiling of key biomarkers in breast cancer patients - PubMed
pubmed.ncbi.nlm.nih.gov
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New in Med by Cell Press: TMEscore model predicts response to immune checkpoint blockade plus chemotherapy in metastatic gastric cancer by assessing the tumor microenvironment. TMEscore outperforms traditional biomarkers such as CPS and MSI in identifying patients who may benefit from this treatment approach. #TMEscore #immunotherapy #gastriccancer #biomarkers #precisionmedicine #clinicalstudy https://lnkd.in/dyhrdUpc
Tumor microenvironment RNA test to predict immunotherapy outcomes in advanced gastric cancer: The TIMES001 trial
cell.com
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Aspiring IT manager at Microsoft
2moLove 😍 this