Medical Xpress’ Post

Summary: A recent study by Ludwig Cancer Research has identified a metabolic switch, PPARβ/δ, in T cells that influences the creation of long-lasting immunity, boosting the body's ability to combat tumors in cancer immunotherapy. This discovery sheds light on how T cells can transform into memory T cells, enhancing their effectiveness in fighting cancer cells and maintaining immune memory, potentially leading to improved cancer treatments. Hashtags: #CancerImmunotherapy #MetabolicSwitch #Tcells #PPARbeta #CancerResearch Tip: Regular exercise plays a crucial role in enhancing immune function and metabolic health, potentially improving the body's ability to fight off infections and diseases. Incorporate a mix of cardiovascular exercise, strength training, and flexibility exercises into your routine to support overall health and well-being. Hashtags: #ExerciseBenefits #ImmuneHealth #MetabolicHealth #HealthyLifestyle #FitnessRoutine Read more here: https://lnkd.in/e3nYbKwG BioMedHack.com is your leading source for the latest news, breakthroughs, and insights in medicine, biohacking, and alternative medicine. Our mission is to help you live healthier and longer by bringing you cutting-edge information and expert advice. Follow us on Facebook, Instagram, and X.

Harnessing innate immune pathways for therapeutic advancement in cancer https://lnkd.in/gQAxtBRC

Study reveals new insights into immune system role in lung cancer risk

Antigen presenting cells in cancer immunity and mediation of immune checkpoint blockade https://lnkd.in/gu3byFdP

🧑⚕️ The first NHS patients have received an experimental vaccine which health leaders think could revolutionise cancer care and treatment. Using mRNA technology, the therapy is being delivered, and it will target melanoma, lung cancer and other ‘solid tumour’ cancers. 🫁 🗣️: “This research is still in the early stages and may be a number of years from being available to patients, but this trial is laying crucial groundwork that is moving us closer towards new therapies that are potentially less toxic and more precise.” 🔗 Read more here: https://ow.ly/roFl50QyIEQ #HealthLeaders #Health #Healthcare #HealthcareSector #NHS #NHSNews #HealthNews #Cancer #CancerTreatment #HealthTechnology

An immunogenetic basis for lung cancer risk https://lnkd.in/gvEc-5jE

Immunotherapies that mobilize a patient's own immune system to fight cancer have become a treatment pillar. These therapies, including CAR T-cell therapy, have performed well in cancers like leukemias and lymphomas, but the results have been less promising in solid tumors. For daily news and analysis subscribe to the https://lnkd.in/gs95BvE8 newsletter. #Transport #Logistics #Vehicles

A re-engeneered polio virus experimental treatment, which is performed in the Duke Cancer institute, can wipe glioblastoma out from terminal patients who face a death sentence because no therapy works. Glioblastoma is one of the most known agressive brain cancer that have to face a lot of patients all over the world. The virus is the creation of, the obsession of Dr. Matthias Gromeier a molecular biologist who has been laboring over this therapy for 25 years, the last 15 at Duke University. Even though scientific collegues say it was too dangerous, polio virus was Dr Gromeier's choice because as luck would have it, it seeks out and attaches to a receptor that is found on the surface of the cells that make up nearly every kind of solid tumor. The modified virus can't cause paralysis or death because it can't reproduce in normal cells but in cancer cells it does and in the process of replicating it releases toxins that poison the cancer cell. The polio infection in cancer cells awaken the immune system which reacts attacking the tumor, in which, a lot of T-cells were found. To satisfy the FDA they did 7 years of safety studies tests on 39 monkeys to prove they didn't get polio and in 2011 the FDA approved a trial in humans giving them the breakthough status. According to Dr. Henry Friedman's words, one of the world's leading cancer doctors, "This is the most promising therapy, I've seen in my career.” This therapy has also been tested with different types of cancer in the laboratory and it is capable to kill lung cancers, breast cancers, colorectal cancers, prostate cancers, pancretic cancers, liver cancers and renal cancers. Look in the attached link, what they learn from each patient and how they overcome and try to solve all the drawbacks and problems that they have to face during the clinical trial. In addition, one question arises during the clinical trial , why this therapy goes so well for some patients and not for others and how they try to answer it. All the scientists, doctors, patients who fight every day against all these diseases are my real heroes and unfortunately society/goverments don't put the focus on them and give the investment they deserve. Enjoy the 60 minutes documental. https://lnkd.in/e5rn42Tj

PD-1H/VISTA mediates immune evasion in acute myeloid leukemia: https://buff.ly/4bnxLUV Authors Tae Kon Kim, Xue Han, Qianni Hu, Esten N. Vandsemb, Carly M. Fielder, Junshik Hong, Kwang Woon Kim, Emily F. Mason, R. Skipper Plowman, Jun Wang, Qi Wang, Jian-Ping Zhang, Ti Badri, Miguel F. Sanmamed, Linghua Zheng, Tianxiang Zhang, Jude Alawa, Sang Won Lee, Amer M. Zeidan, Stephanie Halene, Manoj M. Pillai, Namrata S. Chandhok, Jun Lu, Mina L. Xu, Steven D. Gore, Lieping Chen #Immunology #Oncology

A new way to spot life-threatening infections in cancer patients Leuko "is developing an at-home white blood cell monitor to give doctors a more complete view of their patients’ health remotely. Rather than drawing blood, the device uses light to look through the skin at the top of the fingernail, and #artificialintelligence #AI to analyze and detect when white blood cells reach dangerously low levels." #medicalai #medical #cancer #wortharead