Motic Scientific’s Post

There's still time to register for today's webinar! 𝐈𝐧𝐭𝐫𝐨𝐝𝐮𝐜𝐢𝐧𝐠 𝐭𝐡𝐞 𝐈𝐧𝐯𝐞𝐫𝐓𝐚𝐮: 𝐂𝐨𝐧𝐟𝐨𝐜𝐚𝐥 & 𝐕𝐢𝐝𝐞𝐨 𝐅𝐋𝐈𝐌 𝐌𝐢𝐜𝐫𝐨𝐬𝐜𝐨𝐩𝐞 #FLIM (Fluorescence Lifetime Imaging Microscopy) is quickly growing in popularity due to its ability to distinguish the #molecular environment of #fluorophores. FLIM provides an additional dimension to standard #widefieldfluorescence imaging, which allows researchers to detect variations of fluorophores that are not apparent with steady-state techniques alone. The new InverTau galvo-scanning confocal FLIM #microscope is fast, accurate, cost-effective, remarkably easy to use, and capable of producing 4k x 4k high-resolution images. ➕ bundled with HORIBA’s revolutionary FLIMera TCSPC camera, users can capture FLIM dynamics at video rates in addition to high-resolution FLIM images. This webinar will cover 👇 🔬The InverTau specifications and features 🔬Demo the EzTime Image software platform’s ease-of-use 🔬The FLIMera’s remarkable FLIM-video capabilities for capturing dynamic-FLIM and quickly scanning samples for regions of interest. Register FREE here: https://lnkd.in/e2nZDx8x #pharma #biopharma #research #design #molecularbiologists #disease #diseaseprogression #drugefficacy #semiconductor #chargecarrier

How does a science with a legacy spanning over four centuries remain pertinent and influential in modern research? NSH Member Alexa Levinson will dive in at her upcoming 2024 NSH Histology Convention education session. Learn more: https://bit.ly/4cLt3Re

Leukocyte Extravasation, the process by which white blood cells, like the macrophages pictured below in cyan, leave the vasculature and enter the tissue space is difficult and hard to accurately capture with standard 2D histology solutions. Using Alpenglow’s 3D Spatial Biology solution, we not only show the macrophages in the tissue space, but we employ our computational tools to quantify the number of cells and cell distance from the vessels to determine the overall degree of migration. Contact us today if this looks like something that could be useful to monitor the biodistribution of your cell therapy, as well as visualize your mechanism of action.   https://lnkd.in/eygbYEgD

Need some advice for the preparation of your experiment at the nanoscale with STELLARIS STED Systems? Read the updated guide to STED sample preparation and find useful hints on the right selection of fluorescent probes for various kinds of STED applications. The new guide includes information on using TauSTED Xtend. 🖼The image shows a two-color confocal vs TauSTED Xtend image of mammalian cells labeled with CF 440 - Phalloidin (glow) and immunostained against tubulin, StarGreen (cyan). #microscopy #sampleprep #STED

Catch the next webinar! 𝐈𝐧𝐭𝐫𝐨𝐝𝐮𝐜𝐢𝐧𝐠 𝐭𝐡𝐞 𝐈𝐧𝐯𝐞𝐫𝐓𝐚𝐮: 𝐂𝐨𝐧𝐟𝐨𝐜𝐚𝐥 & 𝐕𝐢𝐝𝐞𝐨 𝐅𝐋𝐈𝐌 𝐌𝐢𝐜𝐫𝐨𝐬𝐜𝐨𝐩𝐞 #FLIM (Fluorescence Lifetime Imaging Microscopy) is quickly growing in popularity due to its ability to distinguish the #molecular environment of #fluorophores. FLIM provides an additional dimension to standard #widefieldfluorescence imaging, which allows researchers to detect variations of fluorophores that are not apparent with steady-state techniques alone. As this technique expands, higher resolution and faster frame rates are required to match the intricacy and dynamics of #biological processes. FLIM instrumentation is also very costly, preventing some researchers from accessing the many benefits of FLIM. The new InverTau galvo-scanning confocal FLIM #microscope meets these demands: fast, accurate, cost-effective, remarkably easy to use, and capable of producing 4k x 4k high-resolution images. Bundled with HORIBA’s revolutionary FLIMera TCSPC camera, users can capture FLIM dynamics at video rates in addition to high-resolution FLIM images. This webinar will cover: 🔬The InverTau specifications and features 🔬Demo the EzTime Image software platform’s ease-of-use 🔬The FLIMera’s remarkable FLIM-video capabilities for capturing dynamic-FLIM and quickly scanning samples for regions of interest. Don't miss out! Register here: https://lnkd.in/e2nZDx8x #pharma #biopharma #research #design #molecularbiologists #disease #diseaseprogression #drugefficacy #semiconductor #chargecarrier

What is the specific inquiry you aim to resolve through your tissue analysis?

Our new paper entitled 3D atlas of the human fetal chondrocranium in the middle trimester and published in Scientific Data (by Springer Nature Group) is finally online. In this work advanced microCT scanning was used that includes contrast enhancement to generate the first 3D atlas of the human fetal chondrocranium during the middle trimester (13 to 19 weeks). In addition, since cartilage and bone are both visible with the techniques used, the endochondral ossification of cranial base was mapped since this region is so critical for brain and jaw growth. Thanks for all our partners from a wide international team: Joy Richman and Siddharth Vora from The University of British Columbia, Brian Metscher from Universität Wien | University of Vienna and Igor Adameyko from Karolinska Institutet for pursuing this work. Big thanks goes also to Markéta Tesařová, from CTLAB CEITEC of CEITEC - Central European Institute of Technology, who was responsible for microCT scanning, segmentation, creating Figures and writing of the original draft and to Tomas Zikmund for guidance in microCT methodology. The article is Open Access and it is available here: https://lnkd.in/evqZrNcj #CEITECScience #ctlab #3D #atlas #chondrocranium #CT #micro

How does Visiopharm’s software impact the way CRO’s work with clients? 🔍   James Clay, Digital Pathology Manager at HistologiX: “We are doing many more studies now in the spatial biology sphere, like immuno-oncology with lots of multiplex markers. The ability to build spatial relationships how we want, not how it is pre-canned in an algorithm already, is really helpful. Visiopharm has transformed our approach. Before we were always having to fit the study design to the analysis capabilities, whereas now we can fit the analysis approach to the requirements of the study.”   Read the full Q&A with the HistologiX team here: https://hubs.ly/Q024tH3K0 #Phenoplex

Seeing is believing. Coming to ASMS, Single Cell Omni Omics, a true single cell platform that uses sequential analyte detection by MALDI MS. Individual cells are captured, prepped for analyte, visualized, selected, and lasered. Thousands of single cells can be analyzed in minutes. The same cells can be re-prepped for a different analyte, then detected, and repeat. Developed in Anand Mehta laboratory at the Medical University of South Carolina by Jake Dressman and Furkan Bayram , the platform will be presented by Jake on Sunday at the Bruker eXceed symposia, and the software and targeting components by Furkan at the Mass Spectrometry Imaging Workshop on Wednesday afternoon. #glycotime #gogoglycans #IMSIS #spatialbiology #ASMS2024

Checkout the Lumascope 720™ Fully Automated Live Cell Imaging System by Etaluma, Inc. — available now at FroggaBio! Revolutionize your microscopy with walk-away automation, 3-color fluorescence, and high content imaging. 🐸✨ LEARN MORE: https://hubs.li/Q02hs20v0 Explore a new realm of automated microscopy with the Lumascope 720™, offering XY motion control, motorized focus, and compatibility with various objectives. Perfect for live cell imaging at a fraction of the cost! 🔬🌐 #Lumascope720 #Etaluma #MicroscopyInnovation #FluorescenceImaging #HighContentAnalysis #CellCulture #AutomatedMicroscopy #ResearchTools #LabTech #ScientificDiscovery #BioTech #LifeSciences #ImagingSystem #CellBiology #LabEquipment #InnovationInScience #MicroscopeTechnology #FroggaBio #ExploreMicroscopy #LabResearch #ScientificAdvancement #FluorescenceDetection #WalkAwayAutomation #LiveCellImaging #LabInstruments #DigitalMicroscopy #ResearchRevolution #CellVisualization #CuttingEdgeTech #DiscoverMoreWithEtaluma #ExploreTheInvisible