How does the presence of splanchnic vein thrombosis impact the prognosis and survival outcomes of younger patients with polycythemia vera or essential thrombocythemia? Read our latest article to learn more! 👉 https://loom.ly/zg3wa7w #mpn #mpnsm
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Last week, we tested your knowledge on the guidelines-based standard of care for treating #CIDP (chronic inflammatory demyelinating polyneuropathy), a chronic, progressive condition that may require long-term management. 70% of you picked the correct answer – there are several guidelines-based treatment options for CIDP: corticosteroids, immunoglobulins, and plasmapheresis. The path to diagnosis and treatment can be a long process for people living with CIDP. We’re committed to doing our part for patients and moving science forward. Learn more: https://lnkd.in/eM_9wmRe
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Hemolysis in patients with severe #ARDS in VV #ECMO? Cell-free Hb may be a mechanism of injury: 🔍 retrospective study including 147 patients 🩸 higher plasma levels of carboxyhemoglobin & lower of haptoglobin in non survivors 🩸 higher haptoglobin associated with lower PVR & SVR 🩸higher COHb associated with higher PVR 🫁 COHb independent predictor of VAP 🪦 both haptoglobin & COHb, indirect markers of hemolysis, independently predicted #ICU mortality 🩸 iron pathway associated with VAP onset (pre #ECLS transferrin) + mortality (pre ECMO iron levels) Open access #FOAMcc #FOAMecmo on ASAIO Journal 🔓 https://bit.ly/3WvArcm
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Fibrinogen buffers the cytotoxicity of circulating histones in vivo and ratios of histones to fibrinogen help identify critically ill patients at highest risk of mortality, who might benefit from anti-histone therapy. https://lnkd.in/gDWe7Svg Julian Toh | Jun Yong | Simon Abrams | Lijun Wang | Jeremy Schofield | Steven Lane (E-mail) | Amy Cilia La Corte | Susan S. Wang | Robert Ariens | Helen Philippou | Jianfeng Xie | Weiping Yu | Guozheng Wang | Cheng-Hock Toh, CBE, MD, FRCP, FRCPath
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Raynaud’s Phenomenon is a common comorbidity of ME/CFS (Carruthers 2011) Sources: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - Clinical Working Case Definition, Diagnostic and Treatment Protocols (Carruthers et al 2011) https://lnkd.in/ePq2q9xd Myalgic encephalomyelitis: International Consensus Criteria (Carruthers et al 2011) https://lnkd.in/eux5uQ-C #pwME #MECFS #MyalgicE #MyalgicEncephalomyelitis #Fibromyalgia #Fibro #RaynaudsDisease #Raynauds #RaynaudsAwarenessMonth #SRUK
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Three-year outcomes from the Evolut Low Risk TAVR Bicuspid Study with the #Evolut self-expanding, supra-annular bioprosthesis demonstrate low rates of all-cause mortality or disabling stroke, aortic valve–related hospitalization, aortic valve reintervention, myocardial infarction, and clinical valve thrombosis. Read the manuscript here: https://lnkd.in/extEP7Zq Risk Info: bit.ly/3b6cHUi
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Authors systematically evaluated a retrospective cohort of 79 patients with low-risk MDS tested for anti-erythrocyte or anti-platelet autoantibodies to assess their frequency and the efficacy of immunosuppression, particularly with steroids. Blood Transfus 2023; 21: 452-460 doi: 10.2450/2022.0184-22 (https://lnkd.in/dYkDNV_U) Bruno Fattizzo; @Fabio Serpenti; @Francesco Versino; @Giulio Cassanello; @Lilla M. Cro; Marzia Barbieri; @Giorgio A. Croci; @Nicoletta Revelli; Matteo G Della Porta; @Wilma Barcellini #low-riskmyelodysplasticsyndromes, #directantiglobulintest, #autoimmunehemolyticanemia, #steroids, #immunethrombocytopenia
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The Localized #Scleroderma Total Severity Scale (LoTSS) is a new global outcome measure that scores the severity of all affected tissues in patients with juvenile localized scleroderma, with four of five modules focused on extracutaneous manifestations. 🔗https://lnkd.in/eKwJ2pAn
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https://lnkd.in/em2vPhXk Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association “red flags” that should prompt evaluation for CS. These include unexplained high- grade atrioventricular block in an individual <60 years of age, unexplained VA, or echocardiographic findings, including reduced LV ejection fraction (LVEF), regional wall aneurysm, or basal septal thinning in the absence of coronary artery disease or another explanation. #whymri #cardiacmultimodality #sarcoidosis
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Take the JAMA Clinical Challenge A man in his 70s presented with 2 progressively enlarging, painless nodular lesions on the forehead & right cheek, initially observed as erythematous nodules 3 months prior. He noted a gradual increase in size with subsequent central ulceration. Patient also noted the development of blackish crusting. The absence of fever, pain, or discharge from the lesions and immunocompromised status due to kidney transplant in 2004 were notable. What is your diagnosis? Comment your answer below. A. Cutaneous histoplasmosis B. Cutaneous blastomycosis C. Rhinosporodiosis D. Cryptococcosis Friday at 12 pm ET we’ll post the answer.
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MD, Cardiologist 🫀🩺 | Passionate About Advancing Heart Health 🌍 | Lifelong Learner 📚 Committed to Enhancing Cardiology
🎯Discordant High-Gradient Aortic Stenosis: Trust the Gradient! ✔️❌Mean Gradient❌ has got more important role than ❌Aortic Valve Area❌! ✔️All-cause mortality for patients with DHG-AS (MG ≥40 mm Hg & EOA >1.0 cm2 ) was similar to that of patients with concordant severe AS! 🔗@JACCJournals https://lnkd.in/eBC-AhA4 #aorticstenosis #echocardiography
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