Nalu Medical, Inc.’s Post

📢 Abbott secures expanded FDA approval for Proclaim DRG neurostimulation system The expanded FDA approval allows the Proclaim DRG neurostimulation system to provide full-body MRI scans of patients, while they are implanted with the device. Abbott said that its Proclaim is the only FDA-approved DRG technology to provide targeted relief for people with complex regional pain syndrome (CRPS) types 1 and 2 of the lower limbs. CRPS is a rare and painful condition characterised by a continuous or intermittent burning, stinging or tearing sensation and has been found to be more excruciating than childbirth or amputation of a limb. Its Proclaim DRG stimulation can be an effective option for people who suffer from CRPS and struggle to control the pain, said the medical device maker. Abbott neuromodulation vice president Pedro Malha said: “As we continue to work holistically across chronic pain care, we’re excited to see this new MRI expanded indication for our proprietary and unique Dorsal Root Ganglion Stimulation therapy become another valuable tool in the hands of treating physicians helping people get back to living a life on their terms.” In a separate development, Abbott has completed the first procedures using its new Volt Pulsed Field Ablation (PFA) System to treat abnormal heart rhythms, such as atrial fibrillation (AFib). Read more online: bit.ly/3Hnj4TY 📰 Follow Medical Device Developments to receive the latest medical device news daily and to subscribe to our weekly newsletter #MedicalDeviceDevelopments #abbott #crps

𝐅𝐫𝐨𝐦 𝐇𝐖𝐒𝐆 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐭𝐨 𝐂𝐥𝐢𝐧𝐢𝐜𝐚𝐥 𝐏𝐫𝐚𝐜𝐭𝐢𝐜𝐞  Did you know that all HWSG research is based on real-world clinical data collected at Xpert Clinics? One of our recent #HWSG studies identified factors influencing pain and function in 2681 patients undergoing surgical A1 pulley release (#TVR). 𝐃𝐫. 𝐉𝐞𝐫𝐨𝐞𝐧 𝐒𝐦𝐢𝐭, Hand Surgeon at Xpert Clinics, shares how he incorporates these findings into his daily clinical practice: 𝐉𝐞𝐫𝐨𝐞𝐧: "I use HWSG research findings during my preoperative consultations for A1 pulley release to guide patient counseling and manage expectations regarding treatment outcomes. For instance, we now understand that worse pain and function scores at intake, along with ≥3 preoperative steroid injections, predict poorer postoperative outcomes. Patients with worse preoperative symptoms represent a group with a more advanced disease that is more difficult to treat. It's rewarding to see the results of our work reflected in clinical research and to apply these insights in my daily practice." Thank you, Jeroen, great to see how our HWSG research directly impacts everyday clinical care! 🔗 𝐇𝐖𝐒𝐆 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐛𝐞𝐡𝐢𝐧𝐝 𝐭𝐡𝐢𝐬 𝐩𝐨𝐬𝐭:  JE Koopman et al. Factors associated with self-reported pain and hand function following surgical A1 pulley release. J Hand Surg Eur Link: https://lnkd.in/g5ZXrpiC

📅 Join Prof. Dr. Matthias Lars Grünewald on Wednesday, May 8, 2024 | 9:00am CEST | 3:00pm SGT | 5:00pm AEST in this live #ClinicalView webinar for an overview of some clinical outcomes that Surgical Pleth Index (SPI) may enable, and to hear practical tips on its usage during clinical practice. Prof. Dr. Matthias Grünewald will also cover the advantages of combining both analgesia and depth of anaesthesia monitoring in order to help you achieve greater haemodynamic stability and faster patient recovery. hashtag 🔔 Don't miss this opportunity! #patientmonitoring #AoA #depthofanaesthesia #anaesthesiamonitoring #analgesiamanagement

Effective conservative treatment of medial epicondylitis with physical therapy–a case study Timothy Hui British Journal of Medicine and Medical Research 13 (3), 1-5, 2016 Background and Purpose Like other common tendinopathies, there is debate as to whether medial epicondylitis and tendinitis treatment should focus on inflammation or degeneration management. This case study demonstrates the effectiveness of physical therapy when both are addressed. Case Description A patient with bilateral medial epicondylitis and tendinitis recovered with physical therapy directed at both inflammatory and degenerative elements. Soft tissue manipulation, phonophoresis, and electrical stimulation were utilized at areas detected by microcurrent injury detection. Therapeutic exercise in the clinic and home were also utilized. Outcomes In 11 treatments, strength increased from 4/5 to 5/5 or 5-/5. Pain decreased from 8/10 to 0/10 on Verbal Numerical Rating Scale (VNRS). Patient experienced full return to ADLs, no pain or restrictions. Discussion Three aspects were unique to this case. First, soft tissue manipulation was used to palpate and remodel degenerative tissues. Second, microcurrent injury detection mapped out specific areas of injured tissues. Finally, modalities were applied to these specific areas, which changed from the flexor tendon and muscle to the proximal cubital tunnel. Used together, the patient experienced full recovery in a timely manner. This case suggests that tendinitis may be a combination of degenerative and inflammatory elements which should both be addressed in a treatment plan. #snsinstitutions #snsdesignthinkers #designthinking

📢 More good news in clinical trial breakthroughs! 📢 A recent trial exhibited the efficacy and safety of the Alpha stent in treating unruptured intracranial aneurysms. Developed with a unique mesh design to optimise wall apposition, the Alpha stent underwent structural enhancements, ushering in a new era of stent-assisted coil embolisation. ✳️Unprecedented results - Over the course of the study, 35 adult patients with unruptured intracranial aneurysms in the distal internal carotid artery were evaluated: An impressive 97.1% technical success rate was achieved. It excelled in its ability to facilitate smooth deployment and precise positioning, showcasing its remarkable capabilities. ✳️Treatment efficacy - At the 6-month mark, magnetic resonance angiography revealed 91.4% of patients achieving Raymond-Roy occlusion classification (RROC) I – indicative of complete aneurysm occlusion. Additionally, 8.6% of patients achieved RROC II, signalling significant progress towards occlusion. ✳️Safety is key - Amidst these triumphs, safety remained paramount. With meticulous monitoring, only one patient (2.9%) encountered a procedure-related neurological complication. While experiencing hemiparesis due to acute lacunar infarction, the patient's 6-month modified Rankin Scale (mRS) score remained favourable at 1, emphasising the importance of swift and effective intervention. ✳️Implications for practice - The Alpha stent's exceptional efficacy and safety outcomes underscore its potential as a cornerstone in the treatment of unruptured distal ICA aneurysms. With structural modifications facilitating easier delivery and deployment, neurovascular specialists can now navigate complex cases with newfound confidence and precision. #NeurovascularCare #AlphaStent #ClinicalTrials #Aneurysms #InterventionalTreatment

Does this patient have hip OA? How can we diagnose hip OA early without radiographic imaging? Here is the best physical examination for diagnosing hip OA ➡ The Cluster of Sutlive  Sutlive & associates developed a clinical prediction rule (CPR) for the diagnosis of hip osteoarthritis in patients with C/O unilateral groin, anterior thigh, or buttock pain. Though in our current clinical practice Kellgren-Lawrence grading system is the preferred evaluation method for osteoarthritis, utilizing the clinical prediction rule of Sutlive early conservative management of osteoarthritis can be initiated. Additionally, it reduces the need for radiographs. This rule identifies five(05) diagnostic variables which are as follows: 1️⃣ Active hip flexion causes lateral pain. 2️⃣ Active hip extension causes pain. 3️⃣ Squatting aggravates hip pain. 4️⃣ The hip scour test (aka hip quadrant test) with adduction causes lateral hip or groin pain. 5️⃣ Passive internal rotation at the hip is less than or equal to 25 degrees. The preliminary study conducted by Thomas G. Sutlive holds a moderate clinical value as no validation study has been reported yet.  The link to this study is shared below. https://lnkd.in/dAB4rSd7

📢 More good news in clinical trial breakthroughs! 📢 A recent trial exhibited the efficacy and safety of the Alpha stent in treating unruptured intracranial aneurysms. Developed with a unique mesh design to optimise wall apposition, the Alpha stent underwent structural enhancements, ushering in a new era of stent-assisted coil embolisation. ✳️Unprecedented results - Over the course of the study, 35 adult patients with unruptured intracranial aneurysms in the distal internal carotid artery were evaluated: An impressive 97.1% technical success rate was achieved. It excelled in its ability to facilitate smooth deployment and precise positioning, showcasing its remarkable capabilities. ✳️Treatment efficacy - At the 6-month mark, magnetic resonance angiography revealed 91.4% of patients achieving Raymond-Roy occlusion classification (RROC) I – indicative of complete aneurysm occlusion. Additionally, 8.6% of patients achieved RROC II, signalling significant progress towards occlusion. ✳️Safety is key - Amidst these triumphs, safety remained paramount. With meticulous monitoring, only one patient (2.9%) encountered a procedure-related neurological complication. While experiencing hemiparesis due to acute lacunar infarction, the patient's 6-month modified Rankin Scale (mRS) score remained favourable at 1, emphasising the importance of swift and effective intervention. ✳️Implications for practice - The Alpha stent's exceptional efficacy and safety outcomes underscore its potential as a cornerstone in the treatment of unruptured distal ICA aneurysms. With structural modifications facilitating easier delivery and deployment, neurovascular specialists can now navigate complex cases with newfound confidence and precision. #NeurovascularCare #AlphaStent #ClinicalTrials #Aneurysms #InterventionalTreatment

Ophthopedia Update:Is primary trabeculectomy cost-effective for patients with advanced primary open angle glaucoma? Results from the Treatment of Advanced Glaucoma Study economic model: Background/aims Advanced primary open angle glaucoma (POAG) is a lifelong condition. The aim of this study is to compare medical treatment against trabeculectomy for patients presenting with advanced POAG using an economic evaluation decision model. Methods A Markov model was used to compare the two treatments, medical treatment versus trabeculectomy for the management of advanced POAG, in terms of costs and quality-adjusted life-years (QALYs). The uncertainty surrounding the model findings was assessed using probabilistic sensitivity analysis and deterministic analysis. Data for the model came from Treatment of Advanced Glaucoma Study supplemented with data from the literature. The main outcomes of the model presented in terms of Incremental costs and QALYs based on responses to the EQ-5D-5L, Health Utilities Index-3 and a Glaucoma Utility Index. Results In the base-case analysis (lifetime horizon and EQ-5D-5L measure), participants receiving trabeculectomy had on average, an additional cost of £2687, an additional 0.28 QALYs and an incremental cost per QALY of £9679 compared with medical treatment. There was a 73% likelihood of trabeculectomy being considered cost-effective when society was willing to pay £20 000 for a QALY. Over shorter time horizons, the incremental cost per QALY gained from trabeculectomy compared with medical treatment was higher (47 663) for a 2-year time horizon. Our results are robust to changes in the key assumptions and input parameters values. Conclusion In patients presenting with advanced POAG, trabeculectomy has a higher probability of being cost-effective over a patient’s lifetime compared with medical treatment. #Ophthalmology #Ophthotwitter #BJO

📰 **New Practice Guidelines Published in RAPM Journal!** 📰 Delighted to announce the publication of the comprehensive practice guidelines on the **use and safety of corticosteroid injections** in the latest issue of the RAPM Journal. This guideline is a collaborative effort spearheaded by the American Society of Regional Anesthesia and Pain Medicine, alongside several other esteemed societies. 🔍 **Key Highlights:** - **Guideline Scope:** The guidelines cover the safety of injection techniques (landmark-guided, ultrasound, or radiology-aided), the effect of corticosteroids on the efficacy of injectates, and related adverse events. 🛠 **Methodology:** - Experts conducted comprehensive literature reviews and drafted statements and recommendations, refined and voted on for consensus using a modified Delphi process. - The guidelines follow the United States Preventive Services Task Force grading for evidence and strength of recommendations. 📊 **Results:** - **Safety Improvements:** Imaging guidance enhances the safety of certain procedures, including stellate blocks and lower extremity peripheral nerve blocks. - **Specific Benefits:** Non-particulate corticosteroids are beneficial for cluster headaches but not other headaches; provide benefits in transverse abdominal plane blocks and ilioinguinal/iliohypogastric nerve blocks for postherniorrhaphy pain, with minimal benefit for trigger point injections. 💡 **Conclusion:** These guidelines offer crucial recommendations on the use of corticosteroids in sympathetic blocks, peripheral nerve blocks, and trigger point injections, empowering clinicians to make informed decisions for better patient outcomes. A big thank you to all the experts and participants for their dedication and rigorous efforts in developing these guidelines. Your work is instrumental in advancing pain management practices. 📖 Read the full guidelines here: https://bit.ly/3WaCzWW #PainManagement #CorticosteroidInjections #Healthcare #MedicalResearch #RAPM #PatientCare #ClinicalGuidelines

📰 Clinical Research Paper - Extracorporeal Shockwave Therapy Are you considering adding Shockwave to your clinic? The attached recent paper provides a systematic review and meta-analysis of extracorporeal shockwave therapy for knee osteoarthritis. Learn More: https://lnkd.in/eijt_FyQ. #enovis #clinicalresearch #osteoarthritis