NanoPhoria’s Post

Happy to share our recent paper published in Synlett. https://lnkd.in/dHEMMnEz #organic_synthesis

So, its out. Our paper on the collective synthesis of thiosilvatins in Angewandte. Very proud to have been part of this. Read it, it’s good 😊 https://lnkd.in/d2PN_DEC

https://lnkd.in/gu3-XCUQ I am happy to share you all one of my research article on amide bond formation and esterification by using pyfluro as reagent published in chemcom.

I am excited to announce that our new paper, "2-Methylimidazole-1-(N-tert-octyl)sulfonimidoyl Fluoride: A Bench-Stable Alternative to SOF4 as Precursor to N,O-Substituted S(VI) Compounds" has been published in Angewandte Chemie. In this work, we synthesized 2-methylimidazole-1-(N-tert-octyl)sulfonimidoyl fluoride (ImSF) on a gram scale via double fluorination of t-OctNSO. ImSF is a novel, bench-stable analogue of SOF4 which showed to be an interesting starting material for chiral sulfurimidates and sulfuramidimidates. A huge thank you to Fedor Miloserdov and Han Zuilhof who made this possibble! Read the full publication here: https://lnkd.in/ePsSzH7K

Establishment of a low-cost synthetic route for the intermediate Sutezolid with development of a new method for constructing thiomorpholine rings and for reducing nitro groups without using transition metals Successful demonstration of a three-step process on a 100g scale by Dr. Ryan C. Nelson et al. https://lnkd.in/gUmPdK5E #processchemistry #drug #tuberculosis

I know, that it's a bit out-dated, but I finally forced myself to post it. I'm happy to introduce my recent published first-author paper about the protection and photodeprotection of oligonucleotides. Protection of oligonucleotides by cyclization is a known concept. However, the further linearization could be a bit tricky. In our work we used a recently descovered photoreactivity including photo-oxidative cleavage of the double bond in BODIPY-based fluorophore. This photoreactivity combined with the cyclization of the oligonucleotide by such phototether leads to the full linearization of the oligonucleotide and therefore to the restoration of its original function and an effective base-pairing. https://lnkd.in/eRcP8-Jc

This is our latest paper that demonstrate diversified role of proprietary diazirine-grafted polycaprolactone-polyol bioadhesive, as color-changing indicator of bacterial attack at catheter insertion cite. https://lnkd.in/grAnWEzi!

Curious about how it all started? Hear from our co-founder Pritesh Asher, the brains behind Juicy Chemistry, himself. Countdown to 10 years begins! ⏰ #Chemistryis10XJuicier #juicychemistry #organicskincare #organicwellness

Have a look at CHIMIA Journal's exciting special volume, devoted to Scientific Integrity, with a particular emphasis on chemistry, entitled "Scientific Integrity: Added Constraint or Best Practice?" that was edited by Edwin Constable, member of ENRIO, here: https://lnkd.in/eJmdJPfq

As a physicist I find such publications very helpful for highlighting Research Integrity as "an issue for all scientists who should embrace the promotion of best practices in their own disciplines," as mentioned at the introduction. This time, we have a valuable perspective from Natural Sciences!