A team of NIH-funded found that in a family with an inherited form of Alzheimer’s disease, those who carried a gene variant called APOE3Ch had a delay in cognitive impairment and dementia. More research is needed to see whether APOE3Ch has a protective effect in people beyond this family and to understand how it exerts its protective effect. Learn more about the study: https://lnkd.in/eFizifXg #NIAFunded #NIHAging #CognitiveImpairment #APOE3Ch
National Institute on Aging (NIA)’s Post
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Our last paper was published in the BioMedInformatics MDPI, trying to identify the presence of mutations in ApoE gene in Italian AD population via machine learning approach Thanks to all coworker #med #alzheimer #neurodegeneration #research
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Postdoctoral Research Fellow at ICMR- National Institute of Cholera and Enteric Diseases
Research indicates that individuals with fewer CAG repeats in the HTT gene, often considered milder, exhibit similar cognitive abnormalities to those with more repeats. However, they are less likely to have chorea and are detected later. This suggests neurologists should consider Huntington's disease in elderly patients without typical chorea. https://lnkd.in/gnXbqHgy #huntingtonsdisease #HDpatient #HDnews #neurodegenerativediseases
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Researchers reveal that individuals with two copies of the APOE4 gene variant are almost guaranteed to develop Alzheimer's and experience symptoms earlier. The study, published in Nature Medicine, may redefine this group as having a distinct genetic form of the disease, potentially impacting research, diagnosis, and treatment approaches. The findings highlight the importance of genetic factors in Alzheimer's development and progression. #AlzheimersResearch #GeneticRisk #APOE4Variant #CheckItNow
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MSAT Scientist I Personalized Medicine I Ai/ML| hiPSCs stem cells | Analytics & QC | cGMP | Cell & Gene Therapy | CAR-T ♋I CAR-T | ImmunoTherapy | Gene editing CRISPR🧬✂️ #CAR-T🔬🦠🩸🫁🫀|
Breaking News in Medicine! 🧬 The 2024 #NobelPrize in Physiology or Medicine honors Victor Ambros and Gary Ruvkun for their groundbreaking discovery of microRNA and its transformative role in post-transcriptional gene regulation. Their pioneering work reshapes our understanding of genetic control, opening new horizons for medical breakthroughs and treatments. #NobelPrize2024 #ScientificInnovation #GeneticResearch #MedicalAdvances
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Recent research has shed light on the genetic pathway of neuroblastoma, revealing key genes and mutations involved in its development. This insight paves the way for targeted therapies and personalized treatments for patients. 🧬 #Neuroblastoma #GeneticPathway #ResearchAdvances
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Gene Discovery Links Obesity and Postnatal Depression, Offers Treatment Hope In a groundbreaking discovery reported in Cell, scientists have pinpointed a gene crucial for regulating both obesity and postnatal depression. The gene, known as the TRPC5 gene, was identified through a study involving two boys exhibiting severe obesity and behavioral issues, alongside their mothers who suffered from postnatal depression. This gene, located on the X chromosome, was found to be missing in both boys and inherited from their mothers, who also showed signs of obesity and postnatal depression. Know in Detail: https://lnkd.in/dH7wAiMg #genediscovery #obesity #postnataldepression #mentalhealth #treatmenthope #celljournal #xchromosome #genetics #behavioralissues #personalizedmedicine #momhealth #mentalhealthmatters #obesityresearch
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After decades of research, #genetherapy offers tremendous hope for rare diseases, and the treatment is becoming a reality in clinical practice. On #RareDiseaseDay we take a look at the transformative potential of gene therapy for rare diseases, and the critical role of accurate information in empowering clinicians to advance health equity for these unique patient populations. Read the blog >> https://bit.ly/4aau0Rt #rarediseases #dynamedex #micromedex #rarediseaseday2024
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On #RareDiseaseDay, we look at the transformative potential of gene therapy for rare diseases and the critical role of accurate information in empowering clinicians to advance health equity for these unique patient populations. Read the blog
After decades of research, #genetherapy offers tremendous hope for rare diseases, and the treatment is becoming a reality in clinical practice. On #RareDiseaseDay we take a look at the transformative potential of gene therapy for rare diseases, and the critical role of accurate information in empowering clinicians to advance health equity for these unique patient populations. Read the blog >> https://bit.ly/4aau0Rt #rarediseases #dynamedex #micromedex #rarediseaseday2024
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Polycystic #KidneyDisease (PKD) is a life-threatening, inherited disorder that can lead to kidney function problems and kidney failure. Researchers used innovative 3-D modeling and gene editing techniques to learn more about #PKD genetics and potential treatment approaches. Find out how researchers supported by NCATS, the @National Institute of Diabetes and Digestive and Kidney Diseases and the @National Institute of General Medical Sciences are changing the game using #GeneEditing: https://go.nih.gov/f7kDTet
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Associate Professor, Psychiatry and Neurology, at Harvard Medical School, and Director, Multicultural Alzheimer’s Prevention Program at Massachusetts General Hospital | Neuroimaging, Neuropsych & Biomarkers of Dementia
2moThanks for sharing our work! Thanks again for supporting our research! 👍🏼