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Two papers in Nature describe a new genome editing technique that enables the insertion, inversion and deletion of long DNA sequences at user-specified genome positions. A single-step approach could provide an easier method of genome editing going forward. Read the papers: https://lnkd.in/e3z4zjWV https://lnkd.in/er3zdEp9

  • This is figure 1 from the paper from Patrick Hsu and colleagues, which shows that IS110 mobile genetic elements express a ncRNA that is bound by its encoded recombinase.
Sidharth Mohan, PhD

Biophysicist ★ Biotechnologist ★ Creative problem-solver ★ Results-driven

3mo
Philipp Baaske

I make the invisible visible | Co-Founder & CEO NanoTemper | 🧬 Biophysical Tools for Biotech 🧬

3mo

Very proud to see that our NanoTemper Technologies Monolith instrument was used to mesaure the binding affinities of the IS621 RNP for donor and target DNA, as well as for donor and target DNA containing scrambled LD–RD and LT–RT regions.

Patrick Descombes

Group leader & Senior Expert Genomics chez Nestle Research

2mo

Exciting additions to the genome editing / design toolkit. Congrats to the authors

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Grigory Ryzhakov

labhead at Novartis Institutes for BioMedical Research (NIBR)

3mo

Can’t wait to try it out

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Balaram Ghosh, PhD (he/him)

Associate Professor at Birla Institute of Technology & Science-Pilani, Hyderabad & Principal Investigator at Epigenetic Research Laboratory

3mo

Thanks very much

Yue Peng

Creator of The Next Generation Philosophical-Scientific Framework

3mo

How can it be prevented from unethical usage?

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Anna Nikolova

Cybersecurity & Open Source Enthusiast | Promoting Digital Safety

2mo
Jihyun Ju

Ph.D. in Bio, now Global Business Director at Macrogen. Transitioning from biotech expertise to excel in sales, marketing, organizational management, and talent development, currently achieving significant milestones.

3mo

Good to know!

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