Nicole McAlpine’s Post

If you missed Crystal Reitman’s presentation, Understanding the Challenges and Guidelines of Cell and Gene Therapy within Viral Clearance, at BPI US West, the on-demand version is now live! Don’t miss Crystal's discussion on the impact of ICH Q5A R2 and important viral safety principles. Watch now: https://okt.to/rExM0v

The March/April issue of Retina Specialist is out now! Inside, multiple experts cover topics such as gene therapy for nAMD, the impact of anti-VEGF biosimilars, pearls for port delivery system refills, a rundown on Eylea HD & more. Read the new issue at www.Retina-Specialist.com #retina #retinaspecialist

As the year 2023 comes to an end, here is a recap of our on-demand webinars. Now you can catch up on what you missed on topics from cell and gene therapy to biopharma 4.0 and much more. Watch Now: https://lnkd.in/gU2FhGMr

Photochemical internalization is an effective strategy that relies on photodynamic reaction to promote siRNA endosomal escape to successfully achieve RNA interference gene regulation, which can improve the synergy and effectiveness of gene-photodynamic combined therapy. However, how to simultaneously improve the delivery efficiency of siRNA and organic photosensitizers remains a severe challenge. In view of this, the researchers designed a micellar nanostructure (PSNA) self-assembled from polymer-DNA molecule chimeras. https://lnkd.in/gPkhDiVE

📢 𝗜𝗧'𝗦 𝗔𝗟𝗠𝗢𝗦𝗧 𝗛𝗘𝗥𝗘! In just a few more days, we have some very exciting news to share. Stay tuned to our countdown to find out what this mysterious column solution is: https://bit.ly/3SOFwfb Can’t wait? The answer is within this poster presented at the 5th Annual Gene Therapy Analytical Development 2023 Conference in November.

Tomorrow is the start of the CGTP Symposium! Who is ready to discuss challenges in the cell and gene therapy field? #casss #cgtp2024

Ever wondered about the intricate web of logistics behind #cellandgenetherapy #clinicaltrials? From sourcing specialized equipment to navigating regulatory requirements, every step is crucial in bringing innovative treatments to patients in need. We understand the nuances of these complex supply chains and have developed an end-to-end process to support your cell and gene therapy trial every step of the way. » https://bit.ly/3V8YOOd

Are you developing a cell or gene therapy? Make sure you start planning early for your long-term follow-up too! To learn more about the scientific and operational considerations to optimize your #LTFU, check out this white paper developed by me and Delphine Saragoussi, MD, MScPH #RWE #CGT #LTFU https://lnkd.in/eT7UNcWv

🔊 plas·mid /ˈplazmid/ noun: plasmid; plural noun: plasmids a genetic structure in a cell that can replicate independently of the chromosomes, typically a small circular DNA strand in the cytoplasm of a bacterium or protozoan. Plasmids are much used in the laboratory manipulation of genes. #AAV #genetherapy #CDMO #viralvectors #science #research #lifesciences #biotechnology #scienceandtechnology #mrna #cartcelltherapy #lentivirus #plasmid #LVV #Lenti #ATMP #cellandgenetherapy #plasmids #pDNA #GMP #biologics #immunotherapy

What tangible patient outcomes is personalised medicine already bringing? As part of our latest Life Sciences in the Spotlight episode, Jason C. Foster examined the impacts that cell and gene therapies are already having and their potential future impacts. Take a listen below, and for the full conversation, check out the entire episode here: https://lnkd.in/d9KyPSCC #LifeSciences #PrecisionMedicine #PersonalisedMedicine #Pharma #PatientOutcomes