Ogden College of Science & Engineering, Western Kentucky University’s Post

Most of our insights into the whys and hows of biology start with #CellLines. As fundamental as their contribution is however, their authenticity is directly related to the credibility of our findings. This information resource, on #Cellasaurus has links to lectures from renowned scientists in the world who presented at the "Cell lines in the 21st century: challenges and opportunities for reproducible research" symposium, held in Lausanne (Switzerland) at the beginning of 2024 who talk about different aspects of cell line authentications and the value of submitting cell line information to Cellasaurus to obtain an #RRID. https://lnkd.in/gZQ-fnWT

STUDENT PUBLICATION Melina Stefanou, who is a student of the Master’s Program Clinical Biochemistry–Molecular Biology, Biology Department, National Kapodistrian University of Athens, wrote an excellent review entitled "The role of APOE in Alzheimer's disease". The review is published in the Student International Biological and Biomedical Research magazine that is created so that master’s students could also publish essays. You can find the review at https://lnkd.in/dntkXj7b

Ben-Gurion University Researcher Receives $1.35 Million Grant from The Human Frontier Science Program ! Prof. Michael Meijler of Ben-Gurion University of the Negev (BGU) has been awarded a significant grant from the Human Frontier Science Program (HFSP), supporting innovative, independent, and original research in the life sciences field. The grant, totaling $1.35 million over three years, will support Prof. Meijler's research in chemical biology at BGU and the NIBN | The National Institute for Biotechnology in the Negev (NIBN). His project focuses on disrupting bacterial communication to combat infections. The HFSP, known for its rigorous selection process, chose Prof. Meijler's proposal as one of 34 from a pool of over 700 applications worldwide. This funding underscores BGU's ongoing contributions to scientific research and its efforts to address critical global health challenges. For more information: https://lnkd.in/gFrb6FJe #ResearchFunding #HFSP #GlobalHealth #ChemicalBiology #Bacterialcommunication

New findings by University at Buffalo researchers reveal that RNA editing may play a larger role in human biology and in the development of human disease than has generally been understood. Published in Communications Biology, the study’s authors — including Peter L. Elkin, MD, professor and chair of the Department of Biomedical Informatics at the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo — conclude that the work provides evidence for a more nuanced understanding of how molecular biology works, especially in terms of how proteins and genes respond to environmental challenges. » Read the full story: http://ms.spr.ly/6047YvaYF #UBuffalo #RNAEditing #BiomedicalInformatics #MolecularBiology

Have a look at the short video in this article, where researcher Nastassia Knödlseder, PhD explains the latest advances in the MELIS-UPF Translational Synthetic Biology Laboratory in the creation of living pills. #acnetreatment #syntheticbiology #research #Barcelona https://lnkd.in/dvVG4Mfg

Want to find out more about NMR for biology research? Check out this insightful video featuring Dr. Al-Hashimi discussing their research on the Structure and Dynamics of Nucleic Acids and the role NMR methods played in their work. https://lnkd.in/ekER36VS. #NMR #BiologyResearch #StructuralBiology #ResearchMethods

In a paper in Nature Communications Biology, researchers from Hokkaido University in Japan explored that 'Overcoming thermostability challenges in mRNA–lipid nanoparticle systems with piperidine-based ionizable lipids'. As shown below： a Lipid structure was expanded with three different cyclic amine moieties, CL6F 14-12, CL16F 14-12, and CL17F 14-12. b Predicted impurity structures when each ionizable lipid was oxidized and subsequently hydrolyzed. c Relative amount of aldehyde impurities in additional lipids was evaluated using NBD-H. d After incubation of FLuc mRNA and lipids in the simplified model, adduct formation was estimated using reversed-phase ion pair chromatography. e Fluc mRNA/LNPs were formulated using CL6F14-12, CL16F 14-12, and CL17F 14-12. For fresh LNPs and LNPs stored for 60 days at 4 °C, the bioluminescence was captured using IVIS 6 h after i.v. administration of LNPs. The relative change in total luminescence from the liver is shown in the graph (0.1 mg/kg FLuc mRNA per mouse, n = 3 biologically independent mice per group). Data were analyzed using the paired Student’s t-test. https://lnkd.in/g8DpZ2CZ

#hiringalert Postdoctoral Associate, Rutgers University: The laboratory is dedicated to exploring the molecular mechanisms of antiphage immunity in bacteria and archaea, explicitly focusing on understanding the function and process of CRISPR-associated nucleotide signalling. Additionally, the lab strives to create innovative instruments for the rapid and precise detection of nucleic acids and the identification of human ailments, utilizing the knowledge acquired from our foundational investigations. The approach is multidisciplinary, merging the fields of biochemistry, cellular biology, microbiology, bioengineering, and structural biology https://lnkd.in/gpijSJ43

We are opening two PhD positions to investigate the genetic and molecular bases of the growth-immunity trade-off in plants! 👇 We want to understand why plants reduce their growth during an immune response, even if they are resistant to pathogens, and how they recover. An ideal candidate has an affinity to both computational and molecular laboratory research. The deadline for application is June 17, 2024. Arabidopsis (embedded in the program CropXR): https://lnkd.in/eFgUi4kV Lettuce (capitalizes on the program LettuceKnow): https://lnkd.in/eVzsWG8V Although the positions differ in the object (lettuce or Arabidopsis) and methodologies for the computational component, both center around the curiosity-driven collaborative research of the same phenomenon. So, if in doubt about which position to choose, please apply for both! #PhD #Immunity #Growth #Lettuce #Plant