Opthea’s Post

🌟 Exciting news from the SQUEEZE project! 🌟   We are thrilled to announce the first patient visit for our #MethMex trial, coordinated by our dedicated team at the Medical University of Vienna, under the expert guidance of Karolina Anderle and Helga Lechner-Radner. This milestone marks a significant step forward in our journey to optimize the methotrexate dose and route for #RheumatoidArthritis patients.   💉🔬 The MethMex trial, officially known as the Methotrexate Dose Route Optimization Trial, aims to enhance treatment effectiveness and improve patient outcomes. After overcoming the necessary steps required to launch the clinical trial, we are proud to now have officially started our study in Vienna.   🌍 With Vienna leading the way, visits in Solna (Sweden), Leiden (Netherlands) and Oslo (Norway) - our other clinical centers for the MethMax Trial approved by regulatory authorities - are soon to follow. Stay tuned as we continue to advance this important research, making strides toward better treatments for #RA.   #ClinicalTrials #HorizonEurope #EUproject #HADEA #ClinicalStudy #MedicalResearch #SQUEEZE #InnovationInHealthcare

This event will focus on the potential of sozinibercept to transform patient outcomes by delivering superior vision gains in wet age-related macular degeneration (wet AMD), with KOL perspectives on: 1. The wet AMD treatment landscape and unmet medical need addressed by sozinibercept’s novel mechanism of action; 2. The Phase 2b data demonstrating superiority in combination with standard-of-care therapy; and, 3. The company's two ongoing global Phase 3 registrational trials (COAST and ShORe) evaluating sozinibercept in combination with standard-of-care VEGF-A inhibitors. Additionally, Opthea will provide a strategic outlook. A live question and answer session will follow the formal presentations. Register to attend here: https://lnkd.in/e7SfvNYv #AMD #AMDResearch #biopharma #eyehealth #maculardegeneration #medicaleducation #Opthea #retinalspecialists #wetAMD #WetAMDClinicalTrials #wetAMDstudies

Get up to speed on the latest information on biosimilars. Mark your calendars for this enlightening session during the NASP Conference! Amanuel Y. Kehasse, PharmD, PhD will share insights on biosimilar adoption and its integration into clinical practice. 💡 #biosimilars #healthcareinnovation #NASP2023 #speakersession #specialtypharmacy

2024 marks another exciting chapter for Nucleus Network’s growth tracjectory with the addition of our up coming 3rd dedicated Phase I unit in Sydney. If would like to find out more about this expansion or simply want to know more about the clinical trial landscape in Australia, feel free to reach out for a chat. #nucleus #clinicaltrials #phase1

Nucleus Network will be taking first-in-human (FIH) clinical trials to the next level in 2024 with the recent announcement of its Australian Eastern Seaboard expansion into New South Wales. The addition of the new 70-bed facility in Sydney’s NorthShore Health Precinct, together with expanded Melbourne operations and existing Brisbane and Minneapolis facilities, will see Nucleus Network increase its global bed capacity by almost 40%. Expected to open in Q4 of 2024, the addition of the Sydney clinic, together with expanded Victorian operations in Melbourne and Geelong, and existing Brisbane and Minneapolis facilities is expected to allow the commencement of at least 40 more studies each year, increasing Nucleus Network’s global FIH clinical trial capacity across its sites. Having successfully delivered more than 1000 Phase 1 clinical trials and with expertise in providing innovative clinical trial solutions for global sponsors, this strategic investment reinforces Nucleus Network’s commitment to provide customers with multi-region clinical research support. #clinicaltrials #australia #biotech Teena Pisarev Chris Hickey Jeffery Wong Stewart Walker Chen Huang Kathlyn Tilley Yi (Amy) Ai

// NASH/MASH clinical trials // Why is integrating PROs into studies on NASH crucial? Kayentis has the tools and experience to make your NASH clinical trials successful! #kayentis #eCOA #ePRO #DCT #NASH

Important milestone for our company as we announced early completion of enrollment in LunAIRo, Apnimed’s Phase 3 #OSA #clinicaltrial examining the efficacy and safety of AD109 compared to placebo at six-months and one-year. We believe AD109 has the potential to be the first nighttime oral pharmacologic treatment for people with obstructive #sleepapnea who are either intolerant of, or refuse to use, positive airway pressure therapy. We want to thank the patients who volunteered to participate in this study, extend our gratitude to the investigators for their support and give a shout out to our amazing clinical and medical colleagues who made this important step possible. Topline data expected mid-2025. Learn more about the study design and its presentation at #ATS2024: https://bit.ly/4draxhP #biotech #innovation

At the American Thoracic Society Conference 2024, 35Pharma will present an engaging oral session titled “6036 – HS135, A Novel Activin and GDF Trap, Is Highly Efficacious in Models of Group 1 and Group 2 Pulmonary Hypertension (PH)” on May 19 at the San Diego Convention Center. This presentation will delve into the preclinical data of HS135 and feature insights on the company’s Phase I novel Activin and GDF inhibitor in models of Pulmonary Hypertension. The forthcoming Phase I clinical trial will be a single-center, double-blind, randomized, placebo-controlled study conducted in healthy postmenopausal women. Key outcomes will include safety, pharmacokinetics, and changes in biomarkers associated with Activin and GDF biology following subcutaneous administration of HS135, with dosing slated to commence in the first half of 2024. To know more about HS135 Phase I Clinical Development, visit: https://lnkd.in/gBC_xRY4 #ATS2024 #35Pharma #PulmonaryHypertension #HS135 #ActivinGDF #ClinicalTrial #Phase1 #Biomarkers #DrugDevelopment #MedicalConference

Congrats to the entire TSTrials and Equipo Ciencia team for their commercial launch. Our team has been privileged to have been working alongside this team over last several months and it has been nothing short of amazing to be part of their story. Our team is looking forward to witnessing their continued impact on #globalpublichealth! Follow TSTrials for the latests updates and developments! #ClinicalResearch #TrialInnovation #TSTrials #EquipoCiencia #PublicHealth #clinicaltrials #sitemanagement

🧬 #UKPGx2024 is here! 🧬 We're at the Royal College of Physicians, London, for a packed day of talks, networking and collaboration in the fields of pharmacogenetics and stratified medicine! See you all very soon! #Pharmacogenetics #Pharmacogenomics #PGx #UKPGx #StratifiedMedicines