Orchard Therapeutics - U.S.’s Post

“Impressive” is a term that fails to honor this astonishing compendium of information, insight, and wisdom. As is typical for newborn screening, we can find here the foundation of data, the logic, and the structural wisdom for what we now call genomic medicine, but which will be known in a few years simply as medicine. 1590 references.

MNSI goes global! Last week we had the privilege of presenting our thematic learning at the International Joint Congress of the International Society of Obstetric Medicine (ISOM) and the Society of Obstetric Medicine of Australia and New Zealand (SOMANZ). We presented several learnings from our safety investigations exploring the following themes: ➡ Think Beyond Sepsis: Common themes from two maternal deaths secondary to haemophagocytic lymphohistioctosis ➡ Review of Maternity and Newborn Safety Investigation reports following maternal death from pulmonary embolism ➡ Learning from maternal Sudden Explained Death in Epilepsy (SUDEP): Thematic analysis of safety investigations in England ➡ First trimester deaths in England from venous thromboembolism associated with hyperemesis: Learning and safety prompts ➡ Deaths in England in the first trimester of pregnancy: national patterns and safety recommendations We will be sharing our posters soon and a webinar series to take a deeper dive into these important learnings. 🔗To express interest in this series of webinars please complete the form at this link: https://lnkd.in/ed5wXZCh

𝐓𝐀𝐏𝐒 𝐚𝐧𝐝 𝐇𝐃𝐅𝐍 𝐚𝐫𝐞 𝐬𝐢𝐦𝐢𝐥𝐚𝐫 𝐢𝐧 𝐭𝐡𝐚𝐭 𝐭𝐡𝐞 𝐌𝐂𝐀 𝐃𝐨𝐩𝐩𝐥𝐞𝐫 𝐮𝐥𝐭𝐫𝐚𝐬𝐨𝐮𝐧𝐝 𝐢𝐬 𝐭𝐡𝐞 𝐨𝐧𝐥𝐲 𝐧𝐨𝐧𝐢𝐧𝐯𝐚𝐬𝐢𝐯𝐞 𝐝𝐢𝐚𝐠𝐧𝐨𝐬𝐭𝐢𝐜 𝐭𝐨𝐨𝐥 𝐭𝐨 𝐝𝐞𝐭𝐞𝐜𝐭 𝐟𝐞𝐭𝐚𝐥 𝐚𝐧𝐞𝐦𝐢𝐚. In maternal alloimmunization, MCA doppler ultrasounds are initiated if antibody titers reach a critical threshold; 1:16 for most antibodies except Kell which is critical at any level OR in a pregnancy where the mother has had a previously affected baby. In TAPS, MCA doppler ultrasounds should be initiated every 2 weeks, alongside the routine fluid checks for TTTS. It’s important to remember that TAPS and TTTS are different diseases, and TAPS presents with no other signs, except in advanced stages. Bi-weekly (every 2 weeks) ultrasounds are recommended from 16 weeks in most countries, and this should include MCA Doppler, DVP for both twins, and umbilical artery flow direction recorded. #MCAMay #AlloHopeFoundation #TAPSSupport #fetalanemia #MCAdoppler #HDFN #maternalalloimmunization The Allo Hope Foundation Fetal Therapy LUMC, Leiden

What is a fetal monitor ? A fetal monitor is a medical device used during pregnancy to monitor the heart rate and other vital signs of the fetus. This helps healthcare providers assess the health and well-being of the fetus, especially during labor and delivery. What is the fetal monitor including? Generally, a fetal monitor typically includes the following components. Ultrasound Transducer: To monitor the fetal heart rate. Tocotransducer: To measure uterine contractions. Display Unit: To show the heart rate and contraction patterns. Recording Device: To document the data for medical records. How to use the fetal monitor in the hospital? Preparation: The healthcare provider explains the procedure to the patient and ensures they are comfortable. Placement of Sensors: The ultrasound transducer is placed on the abdomen to monitor the fetal heart rate, and the tocotransducer is placed to measure uterine contractions. Monitoring: The devices are connected to a monitor that displays the heart rate and contractions in real time. Adjustment: The healthcare provider may adjust the position of the sensors to get the best readings. Recording and Interpretation: The data is recorded and interpreted by healthcare providers to assess the well-being of the fetus. Our hottest fetal monitor BFM-700 AND BFM-700+ are recommendede for u. Own software development, update free of charge. Welcome your kind inquiry anywhere anytime. 😊 🌹 #fetalmonitor #ultrasoundfetalmonitor #medicalproducts #healthcare #fetaldevice

New Post on Neonatal Research Long-term outcomes after preterm birth; the next step https://lnkd.in/e8qHDWfy

A quick summary of the ACOG Committee Opinion on newborn screening with helpful links to professional and patient resource links https://lnkd.in/eKJ92Ji7 #obstetrics #ObGyn #screening #healthcare

Low birth weight has been linked to an increased risk of future diseases, including cardiovascular disease. To address this concern, the Child Health Equity Center champions Kangaroo Care as a low-cost intervention, promoting direct skin-to-skin contact between parents and newborns. This approach is especially valuable in low-resource settings where access to advanced care in a Neonatal Intensive Care Unit (NICU) is limited. What makes Kangaroo Care even more compelling is the strong evidence supporting its short-term benefits, such as reducing neonatal mortality and fostering parental bonding. Importantly, Kangaroo Care is now recognized as both feasible and beneficial not only in NICU settings but also in high-resource environments. Despite this evidence, Kangaroo Care is often considered an auxiliary rather than an essential intervention for premature and low birth weight newborns. However, it's time to rethink this perspective and acknowledge the significant impact Kangaroo Care can have on the well-being and development of these vulnerable infants. Learn more at https://lnkd.in/gP6T3ypH. #ChildHealthEquityCenter #KangarooCare #HealthEquity #Pediatrics #Research #Impact #KidsHealth #PositiveChange

Healthcare for the Next Generation Approximately 7.5 per cent of babies in the UK are born prematurely, according to the Office of National Statistics. Incubators provide a safe and secure environment for preterm babies as they recover and develop, but what should you consider when designing one? Here, Dave Walsha, sales manager at drive system supplier Electro Mechanical Systems Ltd explains. Typically, premature babies will require more care than those born at full term. As their lungs are still underdeveloped, preterm babies will often suffer from breathing issues. Commonly, this presents itself as newborn respiratory distress syndrome (NRDS), a condition found in around half of all babies born between 28 and 32 weeks of pregnancy. Babies with NRDS will struggle to keep their lungs inflated independently, making breathing difficult. Read more here: https://lnkd.in/eH6xEWmy

Fetal monitors play a crucial role in medical centers for several reasons: 1. **Assessment of Fetal Health**: Fetal monitors help in continuously tracking the fetal heart rate and other vital signs, providing real-time data on the health and well-being of the fetus during pregnancy and labor. 2. **Detection of Distress**: These monitors can detect signs of fetal distress, such as abnormal heart rates or patterns, enabling timely interventions that can prevent complications or adverse outcomes. 3. **Guidance for Delivery Decisions**: Monitoring assists healthcare providers in making informed decisions regarding the timing and method of delivery, whether to proceed with a natural birth or to consider a cesarean section if the fetus is in distress. 4. **Evaluation of Uterine Activity**: They also track uterine contractions, allowing healthcare providers to assess labor progress and manage pain relief, and detect any abnormalities in contraction patterns. 5. **High-Risk Pregnancies**: For high-risk pregnancies, continuous fetal monitoring is particularly important to ensure both maternal and fetal safety, allowing for early detection of potential problems and prompt interventions. 6. **Documentation and Legal Protection**: The data collected can serve as a record of fetal well-being and labor progression, which can be useful for medical documentation and in legal contexts if needed. 7. **Maternal Peace of Mind**: Knowing that the fetus is being continuously monitored can provide reassurance and reduce anxiety for expectant mothers, contributing to a more positive childbirth experience. Overall, fetal monitors are essential tools in ensuring the health and safety of both the mother and the fetus during pregnancy and childbirth. #FetalMonitor #CTG #HomeCareProducts #RadiologyEquipment #Endoscopy Equipments #DentalProducts #FirstAidKit #HospitalFurnitures #UltrasoundEquipments #MedicalWeighingScale #PhysiotherapyEquipment #RefurbishedProducts #RespiratoryProducts #CardiologyEquipment #ENTEquipments #GynecologyEquipments #MedicalInstruments #LabEquipments #OphthalmologyEquipment +971501434582 www.thahamed.com.

The Heart as a Mirror: A routine anomaly scan may underestimate the fetal heart especially when there is presence of  repeated pregnancy losses even in young parents. A cardiologist driven analysis of heart unmasks not only the progression from mild to severe fetal cardiac disease.  It also unmasks latent autoimmune maternal disease.  As the presentation to cardiology department was late, we could compare previous images of USG with current echocardiography,  sigh and try to fight the fire.  A lesson again that heart is the clearest mirror. Dr Maitri Chaudhuri  Consultant pediatric cardiologist  # Beyond EFE# AIRD# Fetal Cardiomegaly, dysfunction#Complete heart block  www.babyheart.in