OrciTrials’ Post

In the world of clinical research, patient recruitment is often the greatest challenge. At Lampgen Clinical Research, we’ve seen firsthand how critical it is to have the right strategies in place to ensure trials run efficiently. When these principles are ignored, patient recruitment can falter, impacting timelines and overall study success. Here are 5 key principles that can make or break your enrollment strategy: 1. Strong Sponsor-Site Relationships Maintaining direct, clear communication between sponsors and sites is essential. When third-party involvement clouds the relationship, it can lead to misunderstandings, slower responses, and ultimately, delays in patient enrollment. Sponsors need to actively support sites, not just oversee them. 2. Every Patient Matters Every patient brings value to the study. When sites fail to emphasize the importance of each patient or overlook potential candidates, recruitment numbers drop. Patients must feel valued and understood for recruitment to succeed, which requires dedicated attention from both CRAs and site staff. 3. Data-Guided Oversight Without continuous data monitoring, it’s impossible to know where bottlenecks are forming. Inaccurate or slow data feedback leads to missed opportunities and recruitment shortfalls. By leveraging real-time data, sites can act quickly to address challenges and keep recruitment on track. 4. Thoughtful Trial Design Complex or unnecessary enrollment criteria can deter eligible patients and frustrate sites. Simplifying where possible ensures that recruitment isn’t hindered by design flaws. When enrollment criteria are too restrictive, sites may struggle to meet targets, leading to delays. 5. Enrollment-Driven Decision Making Every decision in a trial should be made with enrollment in mind. When decisions are made without considering their impact on recruitment, patient enrollment suffers. A dedicated focus on how each action affects enrollment ensures that the process moves smoothly. At Lampgen, we ensure that our elite CRAs are well-equipped to manage these challenges, keeping trials on track and patient recruitment at the forefront of every decision. #OncologyResearch #PatientEnrollment #ClinicalTrials #CRAStaffing #DataDrivenDecisions #SponsorSiteRelationships #TrialSuccess #OncologyCRAs #ClinicalTrialManagement #EnrollmentStrategy

Is patient recruitment sabotaging your clinical trials? - High dropout rates - Missed enrollment targets - Compromised data integrity They can lead to costly delays and potential project failure. Here are 3 ways we ensure that doesn't happen to our clients: 1. Early-stage recruitment tools: - Our approach includes targeted social media campaigns and efficient pre-screening processes to strategic media partnerships and a dedicated patient database. 2. Strong investigator network: - Established relationships with trusted investigators with years of collaboration in the field ensure a steady flow of qualified patients. 3. Dedicated recruitment follow-up: - Our compact and flexible clinical team structure allows rapid issue solving and reactivity that cannot be followed with larger clinical teams. Don't let patient recruitment challenges derail your clinical trial. Ready to accelerate your patient recruitment? Let's discuss your current challenges. #clinicalresearch #CRO

48% of sites report patient recruitment and enrollment as a top challenge. A Recruitment Lead can be a valuable tool in your arsenal! See how they can lessen patient burdens and reduce recruitment challenges: https://bit.ly/3xoySEI #Patientrecruitment #ClinicalResearch #PatientCentricity #MedTech

Clinical trials are the backbone of developing new and better medical treatment, but 80% of them are delayed, mainly due to recruitment issues. How can we improve? From my perspective, it would help to 1) Raise awareness among patients about the possibility of participating in a clinical trial. The vast majority (some studies say 85%) of patients do not know about the possibility of participating in a clinical trial. This is a big problem and a responsibility that we in the industry have to work together to improve. 2) Involve patients early in the process. Include the patient perspective in the design phase of the clinical trial. Get input from the relevant patient population on things like the number of site visits, interventions, compensation for transport and other costs, the possibility of DCT or a hybrid trial design. Getting their input early on will minimise the risk of designing a trial that doesn't fit patients' needs. 3) Dedicate the necessary resources to patient recruitment. Recognise that it is a discipline that requires investment to avoid high costs when the clinical trial is delayed due to recruitment issues. 4) Have a plan for post-trial communication. Many clinical trial participants are left without any updates once the trial has ended. But ensuring they receive a 'thank you for your time and effort' message along with the results of the trial is the bare minimum we should aim for. I believe these four steps will improve the problems of recruiting participants for clinical trials. They are not easy solutions, but the steps are something that will benefit clinical research. #ClinicalTrials #PatientEngagement #ClinicalResearch #Patientrecruitment

Breaking Down Clinical Trial Enrollment Challenges: A 55% Hurdle Did you know that 55% of clinical trials fail due to enrollment challenges? Despite best efforts, the complex nature of recruitment makes complete control over all variables nearly impossible. But does this mean we’re at an impasse? Not quite. Here are a few areas ripe for improvement: ✅ Patient-Centric Design: Building protocols with patient needs and preferences in mind can significantly improve participation rates. Flexible visit schedules, reduced study burden, and creating welcoming site environment of comfort & familiarity options are key considerations. ✅ Data-Driven Recruitment Strategies: Leveraging real-world data and AI to identify and target the right patient populations can streamline recruitment efforts. Carefully selected study material ensures both compliance and comfort to the patient. ✅ Diversity & Inclusion: Addressing systemic barriers to participation ensures trials are representative and inclusive, while also tapping into broader patient pools. ✅ Continuous Monitoring: Real-time dashboards and predictive analytics allow for dynamic adjustments to recruitment strategies, addressing issues before they escalate. The goal isn’t to achieve perfection but to focus on incremental, actionable improvements. By embracing innovation and collaboration, we can turn enrollment challenges into opportunities for growth and success. There is lot of scope for creative design solutions that puts patient well-being first while also fulfilling the scientific clinic requirements. What strategies have you seen that work well? Let’s share insights and drive change together! #ClinicalResearch #ClinicalTrials #PatientRecruitment #Innovation #Research #ClinicalStudies #ClinicalTrial #ClinicalTrials #LifeSaving #Pharma #HealthInnovation #CRO #CRA #LinkedInCommunity #ResearchMatters #PharmaIndustry #HealthCareProfessionals #HealthCareHeroes #ScienceInAction #BehindTheScenes #SavingLives

🚀 Transforming Clinical Trials with Block Enrollment: Supercharging Recruitment and Streamlining Timelines 🔍 At Ora, we’re harnessing the power of Block Enrollment to redefine patient recruitment and accelerate study timelines. Our Block Enrollment model is an innovative approach that brings together streamlined recruitment, cost efficiency, and enhanced data quality—all while supercharging enrollment speed. Here’s why Block Enrollment is a game-changer for clinical trials: 🔹 Fewer Sites, Faster Enrollment: With Block Enrollment, we can achieve robust recruitment goals with fewer sites, saving time and cutting logistical complexities. 🔹 Focused Physician Engagement: By concentrating study timeframes, our approach allows physicians to devote full attention to studies, optimizing protocol adherence and reducing variability. 🔹 Standardization Across Sites: With fewer time gaps and consistent visit timing, Block Enrollment helps deliver cleaner data and minimizes errors. 🔹 Enhanced Planning for Sponsors: Sponsors benefit from a recruitment model that’s both cost-effective and highly predictable, keeping studies on track and on budget. Discover more about how Ora’s Block Enrollment model can advance your clinical trials and drive results. Connect with us at https://hubs.la/Q02XylkL0. #Ora #CRO #BlockEnrollment #SuperchargeRecruitment #ClinicalTrials #PatientRecruitment #Ophthalmology #ClinicalResearch

🎯 What is the #1 cause of clinical trial delays? Below expectations. Delayed. Blocked. Does that ring a bell? 👇 It’s 𝗽𝗮𝘁𝗶𝗲𝗻𝘁 𝗿𝗲𝗰𝗿𝘂𝗶𝘁𝗺𝗲𝗻𝘁. Recruitment issues are often the #1 reason for protocol amendments—something I’ve encountered time and time again in my career (unfortunately). Unrealistic timelines, non-existent patients, and high site workloads are just a few of the usual suspects. Here are some of the biggest roadblocks I’ve seen: 🚫 𝗧𝗵𝗲 𝗺𝘆𝘁𝗵𝗶𝗰𝗮𝗹 𝗽𝗮𝘁𝗶𝗲𝗻𝘁: A protocol designed for someone who barely exists. 🌍 𝗚𝗲𝗼𝗴𝗿𝗮𝗽𝗵𝘆 𝗺𝗶𝘀𝗺𝗮𝘁𝗰𝗵: Disease prevalence doesn’t align with site locations. ⏳ 𝗨𝗻𝗿𝗲𝗮𝗹𝗶𝘀𝘁𝗶𝗰 𝘁𝗶𝗺𝗲𝗹𝗶𝗻𝗲s: Recruitment and implementation plans uneralistic from the beginning. 📢 𝗟𝗶𝗺𝗶𝘁𝗲𝗱 𝗮𝘄𝗮𝗿𝗲𝗻𝗲𝘀𝘀: Trials aren’t promoted beyond the investigator’s immediate network. 🏥 𝗦𝗶𝘁𝗲 𝗼𝘃𝗲𝗿𝗹𝗼𝗮𝗱: Busy sites that simply don’t have capacity to prioritize your trial. ⚔️ 𝗖𝗼𝗺𝗽𝗲𝘁𝗶𝘁𝗶𝗼𝗻: Other trials in the same indication capturing more attention. 🚪 𝗗𝗿𝗼𝗽𝗼𝘂𝘁𝘀: Protocols that don’t consider patients’ realities or needs. I’m sure I’m not the only one who’s faced these challenges! If you know what I’m talking about, let’s share experiences! And if you’ve cracked the code on recruitment, please enlighten us with your tips. 😊 I’m thrilled to dive deeper into this topic over the next few weeks, culminating in a special Lunch & Chat on Dec 20th 2024 at 1:00 PM CET with Marija-Jasna Basic as our guest speaker ! 🗓 Save the date—event details are coming soon! Let’s work together to break through recruitment barriers and make clinical trials more effective for everyone. 👉 What about you? What’s the most common recruitment blocker you’ve encountered—and how did you overcome it? ⭐⭐⭐ Hi, I'm Virginie! I support innovative pharma companies in planning and executing their early clinical phases smoothly. Activate the 🔔 to follow me and share your experiences. Let's create a supportive clinops community together!

What are your ideas for improving results in clinical trial recruitment? Dave Beaulieu explains C6’s approach here. https://lnkd.in/eNGhdi7z #ClinicalTrials #ClinicalResearch #ClinicalTrialRecruitment #HealthTech #Pharma #PatientRecruitment