Osmind reposted this
Chief Medical Officer at Osmind. Radically Genuine, Relentlessly Curious Psychiatric MedTech Leader, Harvard Trained
Speaking of anhedonia, at Osmind we recently added two scales specific to anhedonia as it is increasingly emerging as a key symptom that differentially responds to certain interventions like TMS and KOR antagonists are on the way to help as well.
Psychiatrist-Psychoanalyst, Org/Healthcare Consulting, Transcranial Magnetic Stimulation, Neuroscience & Complexity Lover, Doorknob Comments Podcast, Psychology Today Blog ExperiMentations, Vibrant #988, Speaker/Teacher
Remarkable data comparing TMS - Transcranial Magnetic Stimulation - with medication in treatment resistant depression unresponsive to at least 2 medications, with psychotherapy. They found in a direct comparison that TMS was 5.5 times more likely to achieve depression remission (27.1% versus 4.9%) and 2.5 times more likely to achieve at least a 50% improvement (37.5% vs 14.6%). TMS responders showed greater improvement in anxiety and loss of ability to enjoy things ("anhedonia") versus those receiving medications, with similar improvement in rumination, cognitive reactivity, and sleep problems. https://lnkd.in/eH7VEUvi Accelerated TMS protocols have even greater efficacy, and are still emerging https://lnkd.in/eR6muJvv #depression #psychiatry #TMS #psychopharmacology
