Owkin’s Post

Dive into a new era of spatial discovery with Visium HD! 🚀 Enjoy single cell-scale resolution and continuous tissue coverage for your whole transcriptome analysis. 🔬🌟 #SpatialGenomics #VisiumHD #ResearchExcellence"

🌈 You've always wanted -or you really need it!- to implement FAST of The Twinkle Factory in FLIM? Now you can! Just published in Advanced Science. A series of three variants, shortT-FAST, midT-FAST & longT-FAST, featuring differentiable fluorescence lifetimes when bound to the same fluorogenic ligand. Into highly-multiplexed imaging? Into lifetime-responsive biosensors? Into FRET-FLIM? The rest is up to you! 🍭 https://lnkd.in/dgUCd3FM #FAST #splitFAST #FLIM

Great to have been part of Visiopharm's spatial biology webinar series, showcasing how we are using the software at OracleBio to generate robust data. If you missed it, check out the recording below! #oraclebio #visiopharm #digitalpathology

This new paper on ✨Med-Gemini✨ research from @GoogleResearch and @GoogleDeepMind shows how the multimodal and long context capabilities of Gemini 1.5 can be used to get state-of-the-art results on a variety of 2D and 3D medical imaging and genomic risk score tasks. State-of-the-art results in most every medical benchmark examined. Check out the thread by amazing senior author Dr. @AziziShekoofeh for more details! 🧵⬇️

Learn how image features can be applied for different applications to measure the relative location of fluorescence signals and track morphological changes in cell populations. Aaron Middlebrook, Sr. Staff Scientist, BD, will highlight real-time imaging (RTI)–enabled cell sorting applications, experimental design and panel considerations. Watch this webinar on demand > https://lnkd.in/gRn_ni2b #rtisfc #bdbiosciences #flowcytometry #spectral

Learn firsthand how to perform whole slide imaging of 40+ protein markers at unprecedented speed. Join us for a webinar with the AFC Association Française de Cytométrie on April 23 that will showcase a new imaging workflow to identify key cell populations and the spatial context of their interactions in complex tissues. Also hear about recent publications using this approach. Sign in here: https://lnkd.in/gPFja9pE #tissueimaging #ImagingMassCytometry #themoreyouknow

📢Today we share the #Article "Ultrasound Radiomics Nomogram to Diagnose Sub-Centimeter Thyroid Nodules Based on ACR TI-RADS" 👨🔬by Wenwu Lu et al. Find out more here👉 https://lnkd.in/dcZWPF4u Keywords: radiomics; thyroid nodules; thyroid imaging reporting and data system (TI-RADS)

Tired of manual quantification and examination of colonies? Increase your clonogenic assay throughput and reproducibility using live-cell imaging and analysis. ➡️ Automatically quantify the number of colonies in a well  ➡️ Evaluate colony size and circularity  ➡️ Track colony formation over time, label-free Learn more via 🔗 https://bit.ly/3XUEEc7

⚡ 𝗔 𝗡𝗲𝘄 𝗣𝗿𝗼𝘁𝗼𝗰𝗼𝗹 𝗳𝗼𝗿 𝗪𝗶𝗿𝗲𝗹𝗲𝘀𝘀 𝗙𝗶𝗯𝗲𝗿 𝗣𝗵𝗼𝘁𝗼𝗺𝗲𝘁𝗿𝘆 & 𝗕𝗲𝗵𝗮𝘃𝗶𝗼𝗿𝗮𝗹 𝗩𝗶𝗱𝗲𝗼 𝗥𝗲𝗰𝗼𝗿𝗱𝗶𝗻𝗴𝘀 𝗶𝗻 𝗥𝗼𝗱𝗲𝗻𝘁𝘀.  This recently published paper illustrates a protocol for synchronized wireless fiber photometry and video recordings in rodents during behavior! 📈 Fiber photometry is a powerful technique to monitor real-time neural activity by measuring fluorescence signals from specific neuronal populations. Traditionally, this was done using wired setups, limiting natural movement. Now, with wireless systems like TeleFipho (Amuza Inc.), neuronal circuits can be studied during complex, unrestricted behaviors. 📷 This study focuses on VIP+ interneurons in the dorsal CA1 hippocampus of mice, using the ANY-maze 𝗯𝗲𝗵𝗮𝘃𝗶𝗼𝗿𝗮𝗹 𝘃𝗶𝗱𝗲𝗼𝘁𝗿𝗮𝗰𝗸𝗶𝗻𝗴 𝘀𝘆𝘀𝘁𝗲𝗺 to record video and synchronize signals with photometry recordings. This setup ensures precise integration of behavioral data with neural activity, offering a flexible solution for researchers. 𝗞𝗲𝘆 𝗛𝗶𝗴𝗵𝗹𝗶𝗴𝗵𝘁𝘀: 💡 𝗦𝘁𝗲𝗽-𝗯𝘆-𝘀𝘁𝗲𝗽 𝗶𝗻𝘀𝘁𝗿𝘂𝗰𝘁𝗶𝗼𝗻𝘀 for viral injections and optic fiber cannula implantation 💡 𝗗𝗲𝘁𝗮𝗶𝗹𝗲𝗱 𝘀𝗲𝘁𝘂𝗽 𝗮𝗻𝗱 𝗰𝗮𝗹𝗶𝗯𝗿𝗮𝘁𝗶𝗼𝗻 𝗴𝘂𝗶𝗱𝗲𝗹𝗶𝗻𝗲𝘀 for the wireless fiber photometry system 💡 𝗖𝗼𝗻𝗳𝗶𝗴𝘂𝗿𝗮𝘁𝗶𝗼𝗻 𝗳𝗼𝗿 𝘀𝘆𝗻𝗰𝗵𝗿𝗼𝗻𝗶𝘇𝗮𝘁𝗶𝗼𝗻 of fiber photometry and behavioral video recordings 💡 𝗖𝗼𝗺𝗽𝗿𝗲𝗵𝗲𝗻𝘀𝗶𝘃𝗲 𝗴𝘂𝗶𝗱𝗮𝗻𝗰𝗲 on fiber photometry recordings, data extraction, and analysis This methodology is applicable across various rodent models beyond transgenic mice strains and can employ diverse viral constructs carrying genetically encoded calcium indicators (GECIs). In addition to calcium imaging, this methodology is well-suited for studying neurochemical signals using the G-protein coupled receptor activation-based sensor (GRAB) 🔗 Read the full paper at this link 👉 https://lnkd.in/dss86giC *^*^*^*^* 𝘞𝘦'𝘥 𝘭𝘪𝘬𝘦 𝘵𝘰 𝘵𝘩𝘢𝘯𝘬 𝘵𝘩𝘦 𝘢𝘶𝘵𝘩𝘰𝘳𝘴 𝘧𝘰𝘳 𝘵𝘩𝘦𝘪𝘳 𝘵𝘳𝘶𝘴𝘵: 𝘰𝘶𝘳 𝘣𝘦𝘩𝘢𝘷𝘪𝘰𝘳𝘢𝘭 𝘵𝘳𝘢𝘤𝘬𝘪𝘯𝘨 𝘴𝘺𝘴𝘵𝘦𝘮 𝘈𝘕𝘠-𝘮𝘢𝘻𝘦 (www.anymaze.com) 𝘸𝘢𝘴 𝘶𝘴𝘦𝘥 𝘵𝘰 𝘳𝘦𝘤𝘰𝘳𝘥 𝘷𝘪𝘥𝘦𝘰 𝘢𝘯𝘥 𝘴𝘺𝘯𝘤𝘩𝘳𝘰𝘯𝘪𝘻𝘦 𝘴𝘪𝘨𝘯𝘢𝘭𝘴 𝘸𝘪𝘵𝘩 𝘱𝘩𝘰𝘵𝘰𝘮𝘦𝘵𝘳𝘺 𝘳𝘦𝘤𝘰𝘳𝘥𝘪𝘯𝘨𝘴. 𝘞𝘦'𝘳𝘦 𝘨𝘳𝘢𝘵𝘦𝘧𝘶𝘭 𝘧𝘰𝘳 𝘵𝘩𝘦 𝘤𝘪𝘵𝘢𝘵𝘪𝘰𝘯.

Ever wonder the link between immuno oncology and middle earth? Check out this seminar on spatial biology basics to find out!