Pacific BioLabs, Inc.’s Post

Anti-VHH probes: Coated with a cocktail of antibodies against nanobodies from various camelid species to enable their direct binding for quantitation and off-rate analysis - curious? Check out the following webinar:

We are excited to share how Crystal Pharmatech utilizes PBPK modeling for the fastest and most efficient formulation development. Register to attend!   Subject Matter Expert, Ridwan Islam, M. Pharm., Ph.D., will present: “Utility of PBPK Modeling as Step 1 in a 3-Step First Time Right Crystal Pharmatech Formulation”   Abstract: PBPK modelling is a valuable tool to address a much wider range of pharmaceutical applications besides drug-drug interactions. We present here PBPK modeling applications routinely used at our CDMO for in-vitro to in-vivo translation and pharmacokinetic modelling in preclinical species in addition to first-in-human pharmacokinetic predictions. Linking of in-silico quantitative structure–property relationship models with (PBPK) modelling is Step 1 of a tailored Formulation for Phase I. Combined with parameter sensitivity we can clearly identify the key compound API Form and Formulation properties. This leads to the fastest, most efficient formulation development with visibility into future clinical trials.

Systems for Research (SFR) would like to highlight it's partner Refeyn's KaritroMP, the macro mass photometer for informing process development in preclinical settings and early drug development. This pioneering tool performs single-particle analysis, enabling users to visualize distributions of viral particle populations within their samples. It can resolve distinct populations of vectors and reveal changes over time – indicating whether a sample is suitable for further processing and helping users save time and resources. Systems for Research (SFR) is your ultimate companion for Refeyn all across Canada. To read more about the KaritroMP, please visit: https://lnkd.in/e7micNWq To learn more about Systems for Research, please visit: https://sfr.ca/ #massphotometry #particles #analysis #drugdevelopment

There is still time to register! Join us for a groundbreaking discussion on Standardizing Pharmacogenomics Laboratory Processes and Reporting! Panel Talk: Standardizing Pharmacogenomics Laboratory Processes and Reporting Tuesday, March 19th, 2024 | 1:00 PM ET Featuring industry experts: Dr. Vicky Pratt, Kristine Ashcraft, and Glenn Sawyer. Our distinguished panelists will dive into crucial topics such as: • The terminology used to characterize metabolizer status. • Identifying clinically relevant genes and variants for testing. • Aligning supporting evidence from key PGx societies. • Structuring clinical reports to meet requirements. Don't miss this opportunity to be at the forefront of the PGx testing conversation. Register now and secure your spot! For more information visit: https://hubs.li/Q02p63Pl0 Even if you can't attend live, register to get access to the recording and all the valuable takeaways. #PrecisionMedicine #Webinar #PGx #HealthcareInnovation #Pharmacogenetics #Panel #Pharmacogenomics #PGxExperts

The SeromYx team is excited to announce the release of our new white paper titled, "View from the Fc: Five Rules for #mAb Development Risk Reduction." 💡 What you'll learn: 💠 The importance of comprehensive Fc function profiling 💠 The need for whole molecule screening 💠 The impact of the immune complex and Fc engineering on effector function At SeromYx, we specialize in profiling and measuring Fc-driven effector functions, with expertise in both vaccines and #monoclonalantibodies. Our new paper shares valuable insights and lessons learned that could help mAb developers navigate these challenges more effectively. #antibodytherapeutics 🔗 Link to download: https://lnkd.in/dChggSvp

Have you ever wondered how your unique genetic makeup influences your response to medications? Join this insightful webinar on Pharmacogenomics—an field that explores the interaction between genetics and drug response. Pharmacogenomics holds the key to personalized medicine, revolutionizing how we prescribe and tailor treatments to individual patients. By understanding genetic variations, healthcare providers can predict how individuals will respond to medications, leading to safer and more effective therapies. You don't want to miss this webinar. #Pharmacogenomics #NextBio #DNAtesting #PersonalizedMedicine #HealthcareInnovation #Workshop #Genetics #DrugResponse #LearningOpportunity

A very important topic.

🇨🇭 It's not all about CDRs. Discover how #ML-guided protein design is breaking boundaries by optimizing binding affinity, expression, and stability in surprising ways. 👇 Daniel Danciu will share insights on how even significant #CDR modifications—including CDR3—can retain strong binding properties when driven by a custom-conditioned #protein language model. Plus, learn how active-learning can supercharge antibody optimization from early-stage leads. 𝐖𝐡𝐞𝐧? October 9th at 12:45 👑 Franziska Geiger, Jonathan D. Ziegler & myself are looking forward to seeing you there & answer any questions 😎 Cradle x BioTechX

Thank you for sharing Ben Straub! Please read the post below and click through to Jeff Dickinson's recent blog post on PK examples. There will also be an opportunity to see Jeff present at the upcoming PHUSE US Connect 2024 event covering 'Population Pharmacokinetic Analysis Data (ADPPK) Programming in {admiral} and the Pharmaverse. We hope to see you there! #DataSciences #RProgramming #RStats #Pharmaverse

This month, dive into the intricate layers of Multiomics with us! Our advanced approach reveals deep connections between molecules, illuminating disease mechanisms and drug responses. From precision medicine to drug discovery, multiomics is driving breakthroughs. Contact our team for more information. https://bit.ly/3OZ6oGX #Multiomics #MultiomicsMarch #PrecisionMedicine #DrugDiscovery #Psomagen