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Pharmaceutical manufacturers need to ensure the safety of their products. Part of this process is developing a Technically Unavoidable Particle profile (TUPP). SAXOCON can help you design your TUPP to communicate your expectations clearly to your materials suppliers. Read more about TUPPs here: https://lnkd.in/d_uaZizK #Toxicology #Pharmaceuticals #BioSafety

https://lnkd.in/gxs7kQpu Article Title: Visualization of the obscure inhalation stage in inhalation therapy Author(s): Hiroyuki Ohbayashi* Journal: International Journal of Pharmaceutical Sciences and Developmental Research Journal ISSN: 2640-7760 Abstract: The flow of the inhalation procedure during inhalation therapy can be divided into three successive stages: a pre-inhalation preparatory stage, a drug inhalation stage, and a post-inhalation stage. Among these, the second stage, drug inhalation, is the most important and obscure. Using ambiguous verbal expression, the drug inhalation method is communicated to the patient using terms such as strongly, deeply, and slowly. Patients usually determine their optimal method of drug inhalation device independently, based on their own interpretation and understanding of the verbal instructions. This may make the precise inhalation using an inhalation device unpredictable. The Tokico Inhalation Monitor TM (TIM) was developed to resolve the unpredictability of this second (drug inhalation) stage. The TIM can simultaneously measure the inhalation flow rate, duration, and total volume, and display them on the screen in real-time. This mini-review demonstrates the effects of inhalation instruction using TIM, which allows the second stage of therapy, drug inhalation, to be displayed on a screen in real-time. #Asthma #Chronicobstructivepulmonarydisease #Inhalationtherapy #Inhalationmonitor #MedicinalChemistry #DrugDevelopment #Pharmacokinetics #Pharmacodynamics #Pharmacogenomics #Toxicology #Pharmaceutics #Biopharmaceutics #Pharmacognosy #PharmaceuticalChemistry #PharmacyPractice #CommunityPharmacy #HospitalPharmacy #IndustrialPharmacy #RegulatoryAffairs #DrugFormulation#DrugDelivery #PharmacyManagement #PharmaceuticalTechnology #PharmacyEducation #ClinicalTrials

#GSPCR2024 #PharmaceuticalConference #Pharma2024 #GlobalPharma #InternationalPharmaceuticalConference going to be held during #September 18-19 2024 in #Valencia #Spain #Europe #pharmatech #Pharmacology #toxicology #drugdiscovery #drugdevelopment #drugdesign #noveldrugdeliverysystem #clinicalresearch #biopharmaceuticals #pharmaceuticals #pharmaceuticaltechnology

#GSPCR2024 #PharmaceuticalConference #Pharma2024 #PharmaConference inviting #abstracts on #pharmaceutics #biopharmaceuticals #pharmaceuticaltechnology #pharmaceuticalindustry #AI #drugdiscovery #drugdevelopment #clinicalresearch #pharmacology #toxicology #medicinalchemistry #pharmaceuticalanalysis and topics related to #pharma for more details, please contact at pharma@arcsconf.com

https://lnkd.in/gZZpfqdP Article Title: Regarding the measurement of therapeutic adherence Author(s): Sara Malo* Journal: International Journal of Pharmaceutical Sciences and Developmental Research Journal ISSN: 2640-7760 Adherence to chronic therapies among population living in developed countries has been estimated about 50% [1]. This is a matter of concern, since poor adherence is associated with suboptimal clinical outcomes, increased frequency of adverse effects and high healthcare expenses [2]. #MedicinalChemistry #DrugDevelopment #Pharmacokinetics #Pharmacodynamics #Pharmacogenomics #Toxicology #Pharmaceutics #Biopharmaceutics #Pharmacognosy #PharmaceuticalChemistry #PharmacyPractice #CommunityPharmacy #HospitalPharmacy #IndustrialPharmacy #RegulatoryAffairs #DrugFormulation#DrugDelivery #PharmacyManagement #PharmaceuticalTechnology #PharmacyEducation #ClinicalTrials

✅️ Pharmacodynamics: Its Role in the Pharmaceutical Industry! From drug interactions to therapeutic effects, learn its role in rational drug design. Join us on LinkedIn to explore the profound impact of pharmacodynamics on drug efficacy and safety. Visit More : https://lnkd.in/gxUWJN4e #pharmacology #pharmacy #pharmaceuticalindustry #chemotherapy #toxicology

Drug repurposing breathes new life into existing medications, offering faster and more cost-effective treatment options for other patients in need. However, the safety of the repurposed drug for its new application must be validated. At Attentive Science our veteran teams’ experience in #Pharmacokinetics , #Toxicology and #SafetyPharmacology can help you navigate the landscape of drug repurposing. Let's accelerate innovation together. 💡 🥼 💊 Discover how we can support your drug repurposing projects ➡   https://lnkd.in/dbhR7c9c #DrugDiscovery #CRO #Pharmaceuticals #DrugSafety

#GSPCR2024 #PharmaceuticalConference #Pharma2024 #PharmaConference inviting #abstracts on #pharmaceutics #biopharmaceuticals #pharmaceuticaltechnology #pharmaceuticalindustry #AI #drugdiscovery #drugdevelopment #clinicalresearch #pharmacology #toxicology #medicinalchemistry #pharmaceuticalanalysis and topics related to #pharma for more details, please contact at pharma@arcsconf.com

https://lnkd.in/g2vwhsjQ Article Title: Development and Evaluation of Rutin-HPβCD Inclusion Complex Based Mouth Dissolving Tablets Author(s): Hitendra S Mahajan*and Krishna G Bhalkar Journal: International Journal of Pharmaceutical Sciences and Developmental Research Journal ISSN: 2640-7760 Abstract: The objective of the present study was to explore inclusion complex of Rutin to improve the aqueous solubility and dissolution rate along with rapid mouth dissolving tablets for oral drug delivery. Rutin is a BCS class II drug having low aqueous solubility and therefore low oral bioavailability. In the present study, inclusion complex of rutin with hydroxypropyl-b-cyclodextrin were prepared by kneading method. Inclusion complex were characterized by 1H NMR, X-ray diffractometry (XRD), differential scanning calorimetry (DSC) studies, and Fourier transform infrared spectroscopy and evaluated for phase solubility study, saturation solubility and in vitro dissolution studies of plain drug (Rutin) and HPβCD inclusion complex. DSC and XRD study demonstrated that there was a significant decrease in crystallinity of pure drug present in inclusion complex (Rutin- HPβCD), which resulted in an increased dissolution rate of Rutin and 1H NMR studies strongly, confirmed that the inclusion complex has formed. The formulation so prepared were characterized for its disintegration, wetting properties, dissolution studies etc. Inclusion complexation results in improvement in solubility and dissolution rate. The inclusion complexation would be suitable method for dissolution and bioavailability enhancement of Rutin. Inclusion complex prepared by kneading method is promising approach for enhancing dissolution rate which increases oral bioavailability of poorly water soluble drugs. #Rutin #HPβCD #Cyclodextrins #Mouthdissolvingtablets #Inclusioncomplexation #Dissolutionenhancement #Pharmacy #Pharmacology #PharmaceuticalSciences #ClinicalPharmacy #MedicinalChemistry #DrugDevelopment #Pharmacokinetics #Pharmacodynamics #Pharmacogenomics #Toxicology #Pharmaceutics #Biopharmaceutics #Pharmacognosy #PharmaceuticalChemistry #PharmacyPractice #CommunityPharmacy #HospitalPharmacy #IndustrialPharmacy #RegulatoryAffairs #DrugFormulation #DrugDelivery #PharmacyManagement #PharmaceuticalTechnology #PharmacyEducation #ClinicalTrials

https://lnkd.in/g2vQd34A Article Title: Validation of spectrophotometric method for determination of esomeprazole and ciprofloxacin in their pure and dosage forms Author(s): Mohsen M Zareh, Monir Z Saad, Wafaa S Hassan, Mostafa E Elhennawy and Mahmoud M Sebaiy* Journal: International Journal of Pharmaceutical Sciences and Developmental Research Journal ISSN: 2640-7760 Abstract: A novel simple, accurate, sensitive and economical spectrophotometric method has been established and validated for the determination of esomeprazole and ciprofloxacin. The method is based on the oxidation of the studied drug by a known excess of potassium permanganate, followed by measuring the decrease in absorption (∆A) of KMnO4 in acidic medium at wavelength of 525nm. The detection limit is reported to be 1.01 and 1.06µg/mL showing a high degree of sensitivity. The proposed method was successfully validated according to ICH guidelines for the determination of esomeprazole and ciprofloxacin with a highly precise recovery and very low relative standard deviation. Finally, the method was compared statistically with a reference method showing equal accuracy, reproducibility and no significant difference with the reported one. #Spectrophotometric #Esomeprazole #Ciprofloxacin #KMnO4 #ICHguidelines #MedicinalChemistry #DrugDevelopment #Pharmacokinetics #Pharmacodynamics #Pharmacogenomics #Toxicology #Pharmaceutics #Biopharmaceutics #Pharmacognosy #PharmaceuticalChemistry #PharmacyPractice #CommunityPharmacy #HospitalPharmacy #IndustrialPharmacy #RegulatoryAffairs #DrugFormulation #DrugDelivery #PharmacyManagement #PharmaceuticalTechnology #PharmacyEducation #ClinicalTrials