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A 45-year-old man is diagnosed with a T3N1 tumour, identified through oesophagogastroduodenoscopy (OGD). The patient began fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) chemotherapy and underwent surgical resection. After 9 months, CT showed three lung metastases. At this point, the original biopsy was tested for HER2 and found to be positive (3+). He has since progressed on capecitabine and oxaliplatin (CAPOX) and trastuzumab as well as paclitaxel and ramucirumab. What would be the most appropriate next step in managing this patient? Join expert Elizabeth Smyth, MD, FRCP, in this series on patients with HER2+ gastric/gastroesophageal junction (GEJ) cancer.  #PeerVoice #meded #pathology #oncology https://lnkd.in/eTkT44WT

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