Pitzer College’s Post

🔬💡 Unlocking Insights with Molecular Dynamics and Docking Simulations! 💊🧬 Delve into the world of molecular interactions and lead discovery processes through cutting-edge in silico techniques! Molecular dynamics (MD) simulations offer a dynamic perspective on macromolecular receptors and their small molecule ligands, providing invaluable insights into their behavior and function. #MolecularDynamics #MoldrugAISystems #DockingSimulations #DrugDiscovery #ComputationalBiology #Bioinformatics #Science #Innovation #Research #Therapeutics #Biotechnology

Excited to share insights into the revolutionary world of Recombinase Polymerase Amplification (RPA)! Discover how enzymes drive rapid DNA/RNA amplification under isothermal conditions, fueling advancements in diagnostics, research, and biotechnology. Learn about vital components like T4 UvsX Recombinase and Bst DNA/RNA Polymerase, and how SBS Genetech's expertise ensures high-quality enzyme production for your scientific breakthroughs. Explore the future of molecular biology with us! #RPA #MolecularBiology #Biotechnology #Diagnostics #Research

"Excited to share that our research article titled 'Molecular Docking Study, and ADMET Analysis for Synthesized Novel Zn(II) Complexes as SARS-CoV-2 Inhibitors' has been published in the Turkish Computational and Theoretical Chemistry Journal. Check out the article here: https://lnkd.in/d6sHX9iF IF: 2.45 Grateful to my co-authors and the journal for this opportunity. #Research #Chemistry #SARSCoV2 #Publication"

🔬 Our latest scientific paper publication highlighting the use of the ADDobody scaffold as a new nanobody platform 🔬   We are pleased to announce the publication in Structure of a scientific research paper demonstrating the potential to expand the scope of therapeutic applications for ADDomer, with the engineering of a new synthetic nanobody called ADDobody.   📄 Title: Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders 🔗 Link to the Paper: https://lnkd.in/e4nDzrGA   This programme, carried out in collaboration with the University of Bristol, combined synthetic and structural biology methods with selection using ribosome display to produce and validate high-avidity super-binders for detection, binding, and neutralisation of diverse pathogenic or toxic targets, such as snake venom.   Let's continue to push for novel new treatments to address major unmet medical needs. #Innovation #HealthcareAdvancements #nanoparticles #biotechinnovation

🌟 Exploring the Intricacies of Protein-Protein Interactions (PPI) 🌟 At #Pronetbio, we are dedicated to advancing the understanding of protein-protein interactions, a critical foundation of molecular biology. Whether you're exploring signaling pathways or drug discovery, our comprehensive suite of services is designed to support cutting-edge research in this field. 🔬 Our services include: Yeast Two-Hybrid (Y2H) for direct interaction detection; Co-immunoprecipitation (Co-IP) to validate protein complex formation; Surface Plasmon Resonance (SPR) for real-time binding affinity measurements; Mass Spectrometry (MS) to analyze complex interaction networks. From custom protein expression to antibody production and high-quality mass spectrometry, we empower researchers with the tools and expertise needed to explore molecular interactions in depth. Our commitment? Making scientific research simpler, faster, and more efficient. 💡 Discover how our tailored solutions can accelerate your research: www.pronetbio.com #ProteinScience #BiotechInnovation #ProteinInteractions #MolecularBiology #DrugDiscovery #PPI #CoIP #MassSpec #BiotechResearch #Pronetbio #ProNetBiotech

A new paper in ChemCatChem (Chemistry Europe) from the lab of Kevin D. Walker, who calls both Michigan State University Department of Chemistry and Michigan State University Department of Biochemistry & Molecular Biology home! The team behind this paper includes Irosha Nawarathne, Zhen Li, Aimen Al-Hilfi, and Kenneth Merz. "Biocatalytic and Regioselective Exchange of 2-O-Benzoyl for 2-O-(m-Substituted)Benzoyl Groups to Make Precursors of Next-Generation Paclitaxel Drugs" https://lnkd.in/gqqGdizT

Andrew again making peptide conjugation not just easier, but fun too ❗️ 🎉 For those navigating the complex world of conjugate vaccines or targeted therapeutics, simplifying steps like CRM197-maleimide conjugation can make a world of difference. Whether you’re building an in-house process or looking to outsource the development of this critical step, this masterclass is a great opportunity to sharpen your approach. Don't miss out – unless you're already using Fina BioSolutions LLC's Ready-to-Conjugate proteins, in which case, enjoy your extra sleep! 😉 😁 #Vaccines #Conjugation #CRM197 #VaccineDevelopment #BiotechMasterclass #ConjugationTechnology #ProteinEngineering #BiotechInnovation #Therapeutics #LifeSciences #Biopharma

In our recent poll, most people (37%) said that the 𝗯𝗶𝗴𝗴𝗲𝘀𝘁 𝗰𝗵𝗮𝗹𝗹𝗲𝗻𝗴𝗲 𝗳𝗮𝗰𝗶𝗻𝗴 𝗱𝗿𝘂𝗴 𝗱𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆 𝘁𝗼𝗱𝗮𝘆 𝗶𝘀 𝗶𝗱𝗲𝗻𝘁𝗶𝗳𝘆𝗶𝗻𝗴 𝘃𝗶𝗮𝗯𝗹𝗲 𝗱𝗿𝘂𝗴 𝘁𝗮𝗿𝗴𝗲𝘁𝘀, and we understand your pain. Here at IRBM, we use numerous strategies in a coordinated manner, leveraging 𝗼𝘂𝗿 𝗶𝗻𝘁𝗲𝗿𝗱𝗶𝘀𝗰𝗶𝗽𝗹𝗶𝗻𝗮𝗿𝘆 𝗲𝘅𝗽𝗲𝗿𝘁𝗶𝘀𝗲 𝗮𝗰𝗿𝗼𝘀𝘀 𝗰𝗵𝗲𝗺𝗶𝗰𝗮𝗹 𝘀𝘆𝗻𝘁𝗵𝗲𝘀𝗶𝘀, 𝗯𝗶𝗼𝗰𝗵𝗲𝗺𝗶𝘀𝘁𝗿𝘆, 𝗰𝗲𝗹𝗹 𝗯𝗶𝗼𝗹𝗼𝗴𝘆, 𝗮𝗻𝗱 𝗰𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗯𝗶𝗼𝗹𝗼𝗴𝘆 to streamline the drug discovery process. By integrating these approaches, our team of more than 200 scientists can efficiently sift through vast amounts of data and biological samples to pinpoint novel drug targets, thereby 𝗮𝗰𝗰𝗲𝗹𝗲𝗿𝗮𝘁𝗶𝗻𝗴 𝘁𝗵𝗲 𝗽𝗿𝗼𝗴𝗿𝗲𝘀𝘀𝗶𝗼𝗻 𝗳𝗿𝗼𝗺 𝘁𝗮𝗿𝗴𝗲𝘁 𝗮𝗻𝗱 𝗵𝗶𝘁 𝗶𝗱𝗲𝗻𝘁𝗶𝗳𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝘁𝗼 𝗽𝗿𝗲-𝗰𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗿𝗲𝗮𝗱𝗶𝗻𝗲𝘀𝘀. 😂 Want more memes + a lot of other valuable content? Follow us here: https://lnkd.in/dBDQpHTV #targetidentification #drugdiscovery #IRBM #funnyfriday

New Method to Investigate The Structure and Dynamics of Challenging Membrane Proteins #NMR spectroscopy is a versatile method for the investigation of the structure, dynamics and interactions of (bio-)molecules, such as proteins, at high resolution. 💡 A new approach, created by Prof. Franz Hagn and team markedly reduces the complexity of the NMR measurements and heavily facilitates the investigation of large and challenging membrane protein systems of pharmaceutical importance. “With this work, we achieve a breakthrough for future NMR experiments of membrane proteins that always suffered from their high complexity. It can be envisioned that only the functionally relevant part of a membrane protein can be visualized to simplify the experiments even more. Such an approach will speed up the analysis of membrane protein structures and their interaction with drug molecules by NMR.” Prof. Franz Hagn, Institute of Structural Biology, #HelmholtzMunich 👉 Learn more in our news:  https://lnkd.in/dUfqSg3Z #proteins #HighResolution #protein #research #MedicalApproach Technische Universität München #MedicalResearch #DrugDiscovery

When you don't have the resources or bandwidth to pursue certain investigations cross-institutional collaborations can help. Come see how you can form cross-institutional collaborations, what kind of questions can be pursued and other burning questions at the PANIC organized webinar.