Precision Neuroscience’s Post

Event-Related Potentials (ERPs) have been increasingly used to understand the neural mechanisms underlying problems with memory and attention in patients to peak performance in athletes. ERPs are brain responses measured through electroencephalography (EEG) that are time-locked to specific sensory, cognitive, or motor events. By studying ERPs, we can capture rapid neural processes that reflect attention, decision-making, and motor preparation, all critical components of brain functions and brain performance. I will be talking about the the use of ERPs for Neurofeedback Practitioners at the ISNR-Conference in Chicago this year. Register here: https://lnkd.in/dfqn79T8

https://lnkd.in/gp7hNn4Q Precision Neuroscences update. Mapping of human thoughts. A revolutionary initiative. Must watch #Neuroscience #AI #profmkb#GALTER_PROF.MAHENDRA

🧠 Excited to share that our first 5-MeO-DMT paper is now available as a preprint! 🧠 In January, we had the amazing opportunity to spend a month in Mexico with Joel Brierre and Victoria Wueschner, hosting six retreats to gather this EEG data. It feels surreal to now see it come together in the form of a paper. A huge shoutout to the absolute wiz George Blackburne for pulling this off!! "Complex slow waves radically reorganise human brain dynamics under 5-MeO-DMT" - George Blackburne, Rosalind G McAlpine, Marco Samuel Fabuš, Alberto Liardi, Sunjeev K Kamboj, Pedro Mediano, Jeremy I Skipper. https://lnkd.in/e87CHGTk Abstract: 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a psychedelic drug known for its uniquely profound effects on subjective experience, reliably eradicating the perception of time, space, and the self. However, little is known about how this drug alters large-scale brain activity. We collected naturalistic electroencephalography (EEG) data of 29 healthy individuals before and after inhaling a high dose (12mg) of vaporised synthetic 5-MeO-DMT. We replicate work from rodents showing amplified low-frequency oscillations, but extend these findings with novel tools for characterising the organisation and dynamics of complex low-frequency spatiotemporal fields of neural activity. We find that 5-MeO-DMT radically reorganises low-frequency flows of neural activity, causing them to become incoherent, heterogeneous, viscous, fleeting, nonrecurring, and to cease their typical travelling forwards and backwards across the cortex compared to resting state. Further, we find a consequence of this reorganisation in broadband activity, which exhibits slower, more stable, low-dimensional behaviour, with increased energy barriers to rapid global shifts. These findings provide the first detailed empirical account of how 5-MeO-DMT sculpts human brain dynamics, revealing a novel set of cortical slow wave behaviours, with significant implications for extant neuroscientific models of serotonergic psychedelics. ... and massive thank you to F.I.V.E. and Tandava Retreats for supporting this work and hosting us!

The first paper coming out of our collab study with F.I.V.E. and UCL on the neurological effects of 5-MeO-DMT. It was more than a pleasure working with Rosalind McAlpine, George Blackburne, and the rest of the team! #psychedelicresearch #psychedelictherapy #psychedelicscience

I'm biased, but this is some of the coolest psychedelic research to date. The learning uncovered by the incredible team at UCL, in collaboration with Joel Brierre, Victoria Wueschner and the teams at F.I.V.E. and Tandava Retreats is set to revolutionize how we understand psychedelics–especially 5-MeO-DMT–and their effects on the brain. From the abstract: "These findings provide the first detailed empirical account of how 5-MeO-DMT sculpts human brain dynamics, revealing a novel set of cortical slow wave behaviours, with significant implications for extant neuroscientific models of serotonergic psychedelics" Follow Rosalind McAlpine for more on the final print of this paper and stay tuned for some amazing growth at KVI, F.I.V.E. and Tandava! #psychedelicresearch #research #neuroscience #mentalhealth #healing #5meodmt #dmt #science

🎵 What does your brain sound like? Bear with me - 🔎 We know what the brain looks like. ✊ We've all put our fists together and thought "Really? That small?" 🧠 I personally have a brain-shaped stress ball from TTP plc on my desk that has got me through *many* meetings (thanks again for that Alex Stokoe) But what if we examined the brain with our ears instead of our eyes? 📝 In the latest original article for NeuroTechX's Content Laboratory, Tyler Sloan experiments with spike sonification: translating neural activity into anything from piano notes to a full orchestra (https://bit.ly/3Zlewrz). How did it go? "𝐿𝑖𝑠𝑡𝑒𝑛𝑒𝑟𝑠 𝑚𝑎𝑦 𝑒𝑥𝑝𝑒𝑐𝑡 𝑡ℎ𝑎𝑡 𝑠𝑝𝑖𝑘𝑒 𝑠𝑜𝑛𝑖𝑓𝑖𝑐𝑎𝑡𝑖𝑜𝑛 𝑤𝑖𝑙𝑙 𝑝𝑟𝑜𝑣𝑖𝑑𝑒 𝑎𝑛 𝑎𝑒𝑠𝑡ℎ𝑒𝑡𝑖𝑐𝑎𝑙𝑙𝑦 𝑝𝑙𝑒𝑎𝑠𝑖𝑛𝑔 𝑚𝑒𝑙𝑜𝑑𝑦 - 𝑡ℎ𝑖𝑠 𝑖𝑠 𝑛𝑜𝑡 𝑎𝑙𝑤𝑎𝑦𝑠 𝑡ℎ𝑒 𝑐𝑎𝑠𝑒" 🧑⚖️ But - judge for yourself... 🤝 Thanks to Benjamin Schornstein, Shubhom Bhattacharya & Lina Feng Cortéz Palacín for their editing and design support on this one 💡 Learn more about the Content Lab and get involved:  https://lnkd.in/eg8ZGPJH #Neurotech #DataIsBeautiful #DataVisualisation #Neuroscience #NeuroTechX #NTX

Ever wondered how you instantly recognize that barista pouring your coffee or the bus driver waving you on? From strangers passing by to loved ones sharing a smile, our brains process countless bodies every day. But how are our own brains able to effortlessly decoding gestures, understanding expressions, and simply knowing "that's a person"? We offer some answers to this in my first research paper: "𝐅𝐢𝐧𝐞-𝐠𝐫𝐚𝐢𝐧𝐞𝐝 𝐧𝐞𝐮𝐫𝐚𝐥 𝐫𝐞𝐩𝐫𝐞𝐬𝐞𝐧𝐭𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐛𝐨𝐝𝐢𝐞𝐬 𝐚𝐧𝐝 𝐛𝐨𝐝𝐲 𝐩𝐚𝐫𝐭𝐬 𝐢𝐧 𝐡𝐮𝐦𝐚𝐧 𝐯𝐢𝐬𝐮𝐚𝐥 𝐜𝐨𝐫𝐭𝐞𝐱". You can access the full text here: https://lnkd.in/dgC3U2zN Here we recorded multi-unit spiking activity in two neurosurgical patients in or near the extrastriate body area (EBA), a critical region for body perception. To answer our questions, we combined a wide set of experimental stimuli with linear decoding techniques. Our study revealed a remarkable specialization within the brain for processing bodies. Not only did neurons in the EBA show a strong preference for bodies over other objects, but they also exhibited a distinct bias towards recognizing individual body parts – like arms and legs. This ability even extends to simplified forms like silhouettes, or even abstract representations of bodies. #brain #bodymind #neuroscience #bioRxiv #research #computationalvision P.S. I'm always curious, so hit me up if you have any questions or feedback!

Check out this groundbreaking AI-driven 3D brain tissue map from Harvard and Google in this HPCwire article. Witness how this collaboration is reshaping neuroscience, revealing the brain's mysteries as never before. https://bit.ly/4bS5s0r #LifeSciences #GigaIO #HPCwire

"At the base of the brain lies the brainstem, a thick rope of nerve cells that, according to new research, could sustain wakefulness in human consciousness. The findings, by a team in the US and France, bolster previous work and could lead researchers to new understandings of altered states of consciousness, such as comas and vegetative states." Continue reading "On MRI Scans, Scientists Find What Could Explain Altered States of Consciousness" #MRI #mriscan #scientists #alteredstates #consciousness #shoplocal #buylocal #UprightMRIOfDeerfield

Incredible breakthrough in AI and Neuroscience 🧠 As someone deeply interested in Neuroscience and with experience working with people with language disorders, I’m fascinated by how artificial intelligence is improving communication possibilities, even in cases of severe neurological conditions. This article from UCSF demonstrates how AI helped a paralyzed woman regain her voice, transforming brain signals into speech. Seeing machine learning applied to decode brain activity and restore speech is an exciting step forward. It’s inspiring to see how AI can offer such impactful solutions, especially in the field of healthcare, restoring capabilities we thought were lost. Exciting times for AI and Neuroscience! 💡🧠💻 #AI #Psycholinguistics #Neuroscience #Innovation #Healthcare #MachineLearning https://lnkd.in/dvumz_vj