Primrose Bio’s Post

Prima RNApols™ are compatible with any DNA template sequence and length, facilitating the manufacturability of long mRNAs (>10 kb) for self-amplifying mRNA-based drugs, and achieving higher yields per DNA template unit. Work with us: https://bit.ly/3XTud85 #PrimroseBio #PrimaRNApols #mRNA #vaccines #therapeutics

Primrose Bio's innovative RNA polymerases, Prima RNApols™, surpass T7 RNA polymerase (T7 RNApol) across many metrics. T7 RNApol is known to be inefficient and generates unwanted double-stranded RNA (dsRNA) byproducts that may trigger adverse immune responses. Prima RNApols break these barriers by delivering higher mRNA yields, greater purity of target RNAs, and drastically reduced dsRNA levels. Discover more: https://bit.ly/3XBwofj #mRNA #vaccines #therapeutics #PrimaRNApols

🎉 It's been ONE YEAR since Primrose Bio launched to enable the discovery and production of new complex therapeutics and vaccines! 🚀 We are incredibly grateful to our dedicated and talented team, visionary partners, and supportive community who have all played a vital role in our journey. Here's to more innovation and progress ahead to deliver significant value to our pharmaceutical customers! #primrosebio

Primrose Bio's PeliCRM197® is the highest purity CRM197 commercially available. It's also the only commercially sold recombinant CRM197 used in marketed vaccines, with GMP certification since 2011. Get started with a free sample for new customers at: https://bit.ly/4ejlxx3 #CRM197 #Pelicrm197 #vaccines

A Drug Master File (DMF) for PeliCRM197® is maintained with the US FDA to simplify your regulatory filings. Upon request, we provide a Letter of Authorization to permit reference to the PeliCRM197® DMF in your applications. This saves you time and effort by not needing to describe PeliCRM197 as a starting material in your submissions and enables the FDA to reference the DMF in their review of your dossier. Learn more: https://bit.ly/4cT0DE2 #CRM197 #PrimroseBio #vaccinedevelopment

Primrose Bio and ExploRNA Therapeutics will co-develop and offer RNA polymerases and capping compounds, co-optimized to enhance mRNA quality, manufacturing performance, and therapeutic safety and efficacy. This partnership provides mRNA drug developers superior manufacturing solutions and innovative design options through advanced capping chemistry. Read the press release: https://lnkd.in/gmeAKu8g #mRNA #PrimaRNApols #vaccines #therapeutics

We are exhibiting at RNA Leaders USA Congress, taking place September 4-5, 2024 in San Diego, CA. Visit booth #25 to meet with Michele Rubino and Sabrina Baffert, MPH on optimizing mRNA vaccine & therapeutic production. Book a meeting with us via PartneringONE. We are looking forward to it! #RNALeaders #PrimaRNApols #PrimroseBio

Primrose Bio's Diane Retallack, PhD, will be presenting at RNA Leaders USA on September 5, 2024. Join us to learn more about tackling the cost and quality challenges of #mRNA manufacturing to accelerate innovation and commercialization of RNA therapeutics and vaccines. #RNALeaders

Primrose Bio is hiring a Senior Research Associate in our Process Development group. We are seeking a highly motivated individual to support processes involving fermentation, primary recovery, and purification development for internal and external protein products. Join us in San Diego for a dynamic start-up environment, comprehensive benefits, and the chance to expand global health through innovative biologics!

August 1 is RNA Day! We recognize RNA Day on Aug. 1 for AUG (adenine, uracil, and guanine) being the start codon in RNA. Join Primrose Bio in celebrating the versatility and importance of RNA in scientific breakthroughs, from research to innovative vaccines and therapies. #RNADay #mRNA #PrimaRNApols