ProJect Pharmaceutics GmbH’s Post

Are you sure your stopper is dry enough to be safe enough for your lyophilized drug product's stability? Have you ever experienced increase in residual moisture content in your lyophilized drug product and could not explain why? Do you know the moisture uptake capacities & water release characteristics of your lyo stopper? An increased residual moisture content could be caused by incomplete drying of the stopper after sterilization. Some stoppers feature a higher moisture uptake potential, weaker stopper drying kinetics and lower water release characteristics than others. Some stoppers are simply subjected to an inefficient drying process at the CMO – without anyone noticing. Check out our “check your lyo stopper“ service offering: You do not need to have a project running with us. You do not need to disclose your API nor any other details of your drug product. We simply need the sterilization and drying process protocol for your stoppers as performed at your CMO, and some stoppers (~ 100 pcs). Our experts will conduct a comparative evaluation on your stoppers versus modern state-of-the-art stoppers and carefully evaluate stopper drying kinetics, moisture uptake potential & water release characteristic. If you also want to find out whether you are already using a stopper that safeguards your lyo product, contact us at info@project-pharmaceutics.com. To learn more about our fields of expertise visit: https://lnkd.in/e_bPukQ3 #processdevelopment #lyophilization #freezedrying #pharmaceuticalmanufacturing #CRO

Membrane Solutions' SteriPure-B Cartridge Filters use the asymmetric polyethersulfone (PES) membrane's high flux and high capacity to their advantage, giving a higher throughput and better performance than other PES pleated cartridge filters on the market.    We've optimized SteriPure-B PES cartridge filters to slow down the velocity of flow rate decline and increase the particle and colloid capacity on the membrane surface. It results in longer service time and reduces the operating cost of filtration system, the cost of replacement filters, and downtime in many applications, including: · Culture media · Buffers · Large volume parenterals · Bulk pharmaceutical products · Ultrapure water · High-purity chemicals · Wine & beer filtration   Check out the graph to see the CHO serum-free media filtration throughput-pressure drop curves of the 0.2 µm SteriPure-B and two other PES cartridge filters from different brands. Is the high-throughput SteriPure-B PES pleated cartridge filter what your plant needs? Don't hesitate to contact us and explore more about our superior-quality product:Violet.Huang@membrane-solutions.com Ph:8613962559693 #water #quality #pharmaceutical #PES #filter #filtration #chemical

Dextrose Monohydrate Dextrose Monohydrate, also known as Glucose Monohydrate. Dextrose Monohydrate is a white crystalline powder that is derived from corn starch. Dextrose Monohydrate is a natural sweetener that is easily absorbed by the body, providing a quick source of energy. It has a moderate sweetness and is commonly used as a bulking agent in food and beverage production. It can also be used in the pharmaceutical and medical industries as a source of glucose in intravenous fluids. Product Specification: Chemical Name: Dextrose Monohydrate Chemical Formula: C6H12O6-H2O H.S. Code: 1702.30.3100 CAS No: 5996-10-1 Origin: Maize Starch Physical Appearance: Crystal White Powder SEND US YOUR REQUIREMENTS: info@marsoleo.com . . #marsoleo #marsoleochemicals #dextrosemonohydrate #glucosemonohydrate #whitecrystallinepowder #cornstarch #moderatesweetness #bulkingagent #sweetener #BeverageProduction #Confectionery #pharmaceutical #mdedicalindustry #glucoseintravenousfluids #intravenusfluids #qualityingredients #CrystalWhitePowder #marsoleoproducts #processingperfection #intravenousglucose #bulkagent #productspecifications #malaysianexports #oilexportercompany

Check out our newest article on "Complexities related to the amorphous content of lactose carriers" in International Journal of Pharmaceutics X. This article elaborates on the increased attention of regulatory agencies and formulators to amorphous content of lactose in DPI formulations. Amorphous lactose is difficulty to define, different quantification methods exist, it can be unstable over time and QbD studies are challenging to execute. Interested to discuss further on this topic? Reach out to me or one of my colleagues! Thanks to my co-authors Marly Bastiaansen and Lorina Bisharat from DFE Pharma. https://lnkd.in/d6_VD2Y9

Soap and detergents are produced for a wide range of applications in industry. Soap is often a basic ingredient in the process industry and in the cosmetic and pharmaceutical industries. An example is the pumping of industrial detergents; either chlorinated, alkaline or silicate containing detergents. All of these cleaners may well be pumped with an air-operated diaphragm pump. The viscosity of the soap can often be a problem, such as during the transfer pumping action, which can be a problem for centrifugal pumps. Volumetric pumps are a good alternative to centrifugal pumps. Another application is the pumping of soap as a base ingredient for shampoo. If soap residue and build-up cumulates and remains in the pump, the soap will deteriorate and bacterial growth will occur. Because of the potential for contamination from bacteria, sanitary double diaphragm pumps can be used, particularly in the cosmetic and pharmaceutical industries as they are easy to clean during CIP and SIP processes. Find out more about our Verderair diaphragm pumps here: https://bit.ly/4brfXrV #verder #verderliquids #verderair #diaphragmpump

Soap and detergents are produced for a wide range of applications in industry. Soap is often a basic ingredient in the process industry and in the cosmetic and pharmaceutical industries. An example is the pumping of industrial detergents; either chlorinated, alkaline or silicate containing detergents. All of these cleaners may well be pumped with an air-operated diaphragm pump. The viscosity of the soap can often be a problem, such as during the transfer pumping action, which can be a problem for centrifugal pumps. Volumetric pumps are a good alternative to centrifugal pumps. Another application is the pumping of soap as a base ingredient for shampoo. If soap residue and build-up cumulates and remains in the pump, the soap will deteriorate and bacterial growth will occur. Because of the potential for contamination from bacteria, sanitary double diaphragm pumps can be used, particularly in the cosmetic and pharmaceutical industries as they are easy to clean during CIP and SIP processes. Find out more about our Verderair diaphragm pumps here: https://bit.ly/4brfXrV #verder #verderliquids #verderair #diaphragmpump

USP <795> states that pharmacists performing non-sterile compounding must ensure that the finished preparation has its accepted potency, purity, quality, and characteristics. The tests described in USP <61> and USP <62> are used to determine if non-sterile products meet quality requirements. Read more about microbial tests for non-sterile drug products: https://lnkd.in/gY9YDrRS

Alcohol Swab Pads Making Machine -Food Grade (H1) required -Medium-Hi Temp. (approx 140-150⁰C) -Slow rotating (under 200rpm) -Bearing type 6005 -Heaters element inside tube *issue: premature bearing failure caused by temperature *solved with hitemp grease from LUBCON (max 200⁰) #machinery #grease #hitemp #alcoholswab #pharmaceutical #industrial #medical #foodgrade #lubricants #lubrication

𝐘𝐨𝐮𝐫 𝐭𝐚𝐛𝐥𝐞𝐭𝐬 𝐥𝐨𝐨𝐤 𝐥𝐢𝐤𝐞 𝐭𝐡𝐢𝐬 𝐚𝐟𝐭𝐞𝐫 𝐭𝐡𝐞 𝐬𝐭𝐚𝐛𝐢𝐥𝐢𝐭𝐲 𝐭𝐞𝐬𝐭? 😑 Don't worry - we've got you covered! 👇 🤯 This core has caused quite a headache for one of our customers. For hygroscopic plant extracts, a regular coating may not be sufficient. 💡 At BIOGRUND we have solved the problem with a PVA coating ➡ 𝐏𝐕𝐀 (𝐏𝐨𝐥𝐲𝐯𝐢𝐧𝐲𝐥 𝐚𝐥𝐜𝐨𝐡𝐨𝐥) is used in coating to form a protective layer around tablets or other pharmaceutical products. This layer helps enhance stability, particularly for sensitive active ingredients or substances prone to moisture absorption ➡ 𝐃𝐨 𝐲𝐨𝐮 𝐮𝐬𝐞 𝐏𝐕𝐀 𝐜𝐨𝐚𝐭𝐢𝐧𝐠𝐬 𝐟𝐨𝐫 𝐬𝐞𝐧𝐬𝐢𝐭𝐢𝐯𝐞 𝐩𝐫𝐨𝐝𝐮𝐜𝐭𝐬? 💬 If you'd like to see the photo of the final result after stability testing, please drop a comment below 👇 #moistureprotection #troubleshooting #pvacoating

🌡️🏭 Ensuring Precise Temperature Control in Pharmaceutical Warehouses 🌡️🏭 Did you know that maintaining the right temperature is crucial for storing pharmaceutical products? Most medications should not be stored above 25°C, making temperature control a top priority during the design phase. That's where Pharmaceutical Cooling Wholesalers come in! At EcoCooling, we take pride in our efficient and hygienic solutions. Our evaporative coolers use Electrically Commutated (EC) fans, the most efficient on the market. By operating at half speed, we can reduce fan energy use by over 85%. Additionally, our systems fully comply with legionella control regulations, ensuring hygienic operation through principles such as droplet avoidance and regular maintenance. For more information on possible installation techniques or to explore our innovative solutions, contact EcoCooling directly. Together, let's revolutionize pharmaceutical evaporative cooling and ensure the integrity of vital medications! 💊💙 #TemperatureControl #PharmaceuticalCooling #EcoCooling https://lnkd.in/exsbZS-Z