Pulse Biosciences, Inc.’s Post

Nice new paper about the benefits of surgical ablation for atrial fibrillation compared to no therapy during other cardiac surgery (see link below). Over 30,000 patients reviewed in the paper, and like many others before, shows improved survival if AF is treated during other cardiac surgery. Unfortunately 80% of patients received no surgical AF therapy - a trend the CT surgical community must improve. As I’ve said for a while regarding surgical AF therapy: some things are better than other things, but something is better than nothing. At the very least do an excellent LAA exclusion. If you’d like to gain some more insight: Armin Kiankhooy has a great video on CTSNet / Cardiothoracic Surgery Network describing AF team building plus a great baseball analogy for growing your surgical AF therapy skills. Waikato Cardiothoracic Unit #atrialfibrillation #cardiacsurgery #cardiothoracicsurgery #ablation

🔬 Excited to share a new contribution to cardiovascular surgery research! I am pleased to announce the recent publication of our article in the European Heart Journal - Case Reports. As a physician-researcher in the field of cardiovascular surgery, I have had the privilege of working on a fascinating project titled "Veno-arterial extracorporeal membrane oxygenation as perioperative support to redo cardiac surgery for inoperable adult patients: a case series." This study presents a case series exploring the use of extracorporeal membrane oxygenation (ECMO) as perioperative support in redo cardiac surgery for adult patients deemed inoperable. We believe these findings could have a significant impact on how to approach challenging cases, providing new insights and possible solutions. I extend my gratitude to my incredible research team for their hard work and dedication, as well as to the European Heart Journal - Case Reports for providing us with the platform to share our work. 📖 If you're interested in delving into more details, I invite you to read the full article here: https://lnkd.in/eVtmB-uJ I appreciate any feedback and hope that this work inspires future research and advancements in cardiovascular surgery! #CardiovascularSurgery #MedicalResearch #ScientificPublication #ECMO #Cardiology

Minimally Invasive Cardiac Surgery with smartcanula: Superior Drainage, Exceptional Results! Exciting discoveries from a single-center study, November 2022! Our smartcanula (24 Fr) has demonstrated remarkable performance in minimally invasive cardiac surgery, ensuring optimal venous drainage at low negative pressures. Here's a snapshot of the key findings: 🔍 Study Highlights: 📊 Methods: A retrospective single-center study with 58 patients across various procedures. 💡 Scientific Insights: Adequate drainage is pivotal for successful outcomes, fostering blood-less operating fields and minimizing haemodilution. 🚀 Innovation Unveiled: smartcanula facilitates optimal perfusion in Minimally Invasive Cardiac Surgery (#MICS), delivering unparalleled results. 🔬 Results Snapshot: 🕒 Procedure Efficiency: Insertion/removal was uncomplicated, with sufficient drainage in all cases. 📉 Negative Pressure: Achieved at 27.2 ± 12.3 mmHg, ensuring optimal conditions. 🩸 Blood Parameters: Minimal impact on postoperative platelets, lactate dehydrogenase, and leukocytes. 🌐 Conclusions: The venous smartcanula allows for optimal venous drainage at low negative drainage pressures, facilitating sufficient perfusion in MICS. 📚 Authors: Karel M Van Praet, Markus Kofler, Alexander Meyer, Simon H Sündermann, Matthias Hommel, Volkmar Falk, Jörg Kempfert 🔍 Read the Full Study: Explore the comprehensive study in Innovations, November 2022. Together, let's advance cardiac surgery with smartcanula! 💙 🏥 #MedTech #HeartSurgery #CardiacSurgery #MedTechInnovation

🔍 Comparison of Multidimensional Frailty Instruments for Estimation of Long-term Patient-Centered Outcomes After Cardiac Surgery 📚 Earn 1.0 CME Credit 👨⚕️ Authors: Louise Sun, Habib Jabagi MD, BSC, MSc, MLP, FRCSC, Jiming Fang, Douglas Lee 🧑🔬 Key Findings: Significant variations in frailty assessment across different instruments. HFRS showed highest accuracy for short-term, while PFI excelled in long-term predictions. 💡 Clinical Relevance: This study emphasizes the importance of selecting appropriate frailty assessment tools for predicting patient outcomes post-cardiac surgery. It offers insights into optimizing preoperative risk stratification and health resource planning, enhancing patient-centered care. 📖 Read the full article for in-depth analysis and implications for clinical practice. ➡️ https://ow.ly/T7Ga50QlHsq #CardiacSurgery #FrailtyAssessment #PatientCare #MedicalResearch #PhysicianInsights #CME

This study explored the connection between elevated Cold-induced RNA-binding protein (CIRP) levels and the incidence of acute kidney injury (AKI) following cardiac surgery, focusing on surgeries involving cardiopulmonary bypass (CPB). #AKI #CardiacSurgery #CPB

🫀 Advancing Cardiac Surgery with Mechanical Circulatory Support (MCS) 🛠️ Cardiac surgery is evolving, tackling increasingly complex cases with innovative strategies. The integration of proactive mechanical circulatory support (MCS) is crucial in managing perioperative low cardiac output syndrome (P-LCOS), a major predictor of mortality in cardiac patients. 🔍 Key Insights: 1. Early Identification: Recognizing high-risk patients through preoperative indicators like cardiogenic shock and elevated lactate levels. 2. Proactive MCS: Implementing MCS preemptively to prevent severe organ hypoperfusion, rather than reacting after P-LCOS develops. 3. Multidisciplinary Approach: Emphasizing collaboration across specialties for better outcomes. 4. Tailored Strategies: Developing specific MCS plans for conditions such as AMI-CS, valvular surgeries, and pulmonary thromboendarterectomy. 🔬 Benefits of Protected Cardiac Surgery: • Early MCS use improves patient survival rates by mitigating severe complications. • Strategic planning and shared decision-making enhance patient care and ethical considerations. 👥 Collaborative Efforts: Adopting a multidisciplinary approach ensures timely interventions and improved resource utilization, ultimately leading to better patient outcomes. #cardiaccriticalcare #postcardiotomy #shock #MCS #ECMO #proactive #MDTapproach https://lnkd.in/gJT7wikV

This study explored the connection between elevated Cold-induced RNA-binding protein (CIRP) levels and the incidence of acute kidney injury (AKI) following cardiac surgery, focusing on surgeries involving cardiopulmonary bypass (CPB). #AKI #CardiacSurgery #CPB

One recent trend that has interested me while working as a critical care nurse has been the incidence of post operative atrial fibrillation following cardiothoracic surgery. Statistically, our patients have a 25% likelihood of having a post operative atrial fibrillation (POAF) event. This is typically contributed to pericardial inflammation due to oxidative stress and ectopic misfiring as well as often some sort of electrolyte imbalance exists as well. Studies have shown that preoperative administration of a low dose b-blocker to cardiac patients has shown a 48% reduction in risk of POAF. This an ultimately improve patient outcomes as post operative atrial fibrillation is often associated with stroke, thrombophlebitis, MIs and extended hospital stays. This is an area that I believe needs to be researched more extensively so that better treatment guidelines can be made regarding the use of beta blockers in reducing cardiac arrythmia events in patients that are known to be high risk. References: Masuda, Y., Luo, H. D., Kang, G. S., Teoh, K. L.-K., & Kofidis, T. (2020). Meta-analysis of the benefit of beta-blockers for the reduction of isolated atrial fibrillation incidence after cardiac surgery. JTCVS Open, 3, 66–85. https://lnkd.in/eVUDWUx4 Norhayati, M. N., Shaiful Bahari, I., Zaharah, S., Nik Hazlina, N. H., Mohammad Aimanazrul, Z., & Irfan, M. (2020). Metoprolol for prophylaxis of postoperative atrial fibrillation in cardiac surgery patients: systematic review and meta-analysis. BMJ Open, 10(10), e038364. https://lnkd.in/eFdZdpJr

The study aimed to investigate the role of cold-induced RNA-binding protein (CIRP) in the development of acute kidney injury (AKI) following cardiac surgery. Elevated extracellular CIRP levels, particularly associated with prolonged cardiopulmonary bypass (CPB) #CardiacSurgery #CIRP #Kidney

CARDIAC SURGERY Cardiac surgery, or cardiovascular surgery, is surgery on the heart or great vessels performed by cardiac surgeons. It is often used to treat complications of ischemic heart disease (for example, with coronary artery bypass grafting); to correct congenital heart disease; or to treat valvular heart disease from various causes, including endocarditis, rheumatic heart disease, and atherosclerosis.It also includes heart transplantation.The earliest operations on the pericardium (the sac that surrounds the heart) took place in the 19th century and were performed by Francisco Romero (1801) in the city of Almería (Spain), Dominique Jean Larrey (1810), Henry Dalton (1891), and Daniel Hale Williams (1893).The first surgery on the heart itself was performed by Axel Cappelen on 4 September 1895 at Rikshospitalet in Kristiania, now Oslo. Cappelen ligated a bleeding coronary artery in a 24-year-old man who had been stabbed in the left axilla and was in deep shock upon arrival. Access was through a left thoracotomy. The patient awoke and seemed fine for 24 hours but became ill with a fever and died three days after the surgery from mediastinitis.Open-heart surgery is any kind of surgery in which a surgeon makes a large incision (cut) in the chest to open the rib cage and operate on the heart. "Open" refers to the chest, not the heart. Depending on the type of surgery, the surgeon also may open the heart. Dr. Wilfred G. Bigelow of the University of Toronto found that procedures involving opening the patient's heart could be performed better in a bloodless and motionless environment. Therefore, during such surgery, the heart is temporarily stopped, and the patient is placed on cardiopulmonary bypass, meaning a machine pumps their blood and oxygen. Because the machine cannot function the same way as the heart, surgeons try to minimize the time a patient spends on it #snsinstitutions #snsdesignthinkers #designthinking