Rajesh Aggarwal MD PhD FRCS FACS’ Post

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Founder | Digital Health | GI/Bariatric Surgeon | Investor

Dr. Kimberly Gudzune, of The Johns Hopkins University School of Medicine in Baltimore presented this week at the American Association of Clinical Endocrinology (AACE) annual meeting, in a post hoc analysis of the SURMOUNT-1 trial, from MedPage Today. Dr. Gudzune notes of participants who failed to shed 5% of their body weight at 12 weeks, more than 90% ultimately achieved that clinically meaningful level of weight loss at 72 weeks. But only 30% dropped at least 15% of their body weight at 72 weeks, compared to 84% of the early responders – those who lost at least 5% at 12 weeks. Put another way, 1 in 6 of the early responders failed to lose at least 15% in weight at 72 weeks, compared to over two-thirds of the slow responders. My take – we should focus care upon early responders, in order to maximize benefit across a population; which is further exacerbated by cost, supply and access issues. https://lnkd.in/e4Hn2Vjv

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