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HumaTein™ a cell culture biomaterial supplement consisting of full native human ECM (Extracellular Matrix), useful for in vitro 4D bioprinting and cell culturing as well as clinical translational studies @RokitHealthcare https://buff.ly/4bGTZBs #organregeneration#skinregeneration

Enhancing Quality Control in Cell Therapies Cell therapies have revolutionized the field of regenerative medicine, offering promising treatments for a variety of medical conditions. Maintaining the safety, efficacy, and consistency of cell-based therapies is paramount for their successful application in clinical settings. Quality control measures play a vital role in evaluating the quality of these therapies, from development to administration. This article explores the current approaches to quality control in cell therapies, including the utilization of functional measurement techniques such as transepithelial electrical resistance (TEER), to ensure the quality and safety of these promising treatments. https://lnkd.in/gN5PHh8B Stop by booth 1930 to see our novel microinjector for RPE and IO injections and our automated TEER system for high throughput screening of barrier integrity and RPE layer functionality!, ARVO in Seattle, May 5-9. #worldprecision

What can we learn from angiogenesis assays? Learn about in vitro angiogenesis assays and their impact on regenerative medicine in this infographic, sponsored by PromoCell. Download now >>> https://bit.ly/4ecN3gH

The cell therapy field is experiencing a major shift from personalized treatments to scalable, more accessible therapies. While this shift promises to revolutionize disease treatment by making advanced therapies more affordable and available, there are challenges to realizing the full potential of allogeneic therapies, including: 💰Cost efficiency and scalability ⚖️ Variability 💼 Regulatory compliance In my latest article for Manufacturing Chemist, I explore the current state and future trajectory of allogeneic cell therapies and discuss how the industry can usher in a new era of personalized and accessible medicine. Read the full piece below. 👇 https://lnkd.in/gYj4kdwA #CellTherapy #Biotech #GeneTherapy

Non-surgical interventional treatments for knee osteoarthritis: The need for different perspectives, cross-specialty collaboration, and preclinical and translational research https://bit.ly/49HiVqU #OA #Osteoarthritis #KneeOsteoarthritis

Targeting mitochondrial function in #glaucoma using a gene-independent approach by over expressing enhanced NDI1 gene (eNdi1) have shown to reduce #retinalganglioncell loss in a #glaucoma mouse model. I look forward to see the next steps of the work being developed by Vzarii Therapeutics (https://lnkd.in/ewG9PPBF). https://lnkd.in/eeErg_FX

𝐢𝐏𝐒𝐂 𝐂𝐞𝐥𝐥 𝐓𝐡𝐞𝐫𝐚𝐩𝐲 𝐋𝐚𝐧𝐝𝐬𝐜𝐚𝐩𝐞 🧪 55+ therapy developers across 6 countries are advancing the field of iPSC cell therapy. Here are the three pillars of iPSCs: 1. 𝐕𝐞𝐫𝐬𝐚𝐭𝐢𝐥𝐢𝐭𝐲 𝐢𝐧 𝐑𝐞𝐠𝐞𝐧𝐞𝐫𝐚𝐭𝐢𝐯𝐞 𝐌𝐞𝐝𝐢𝐜𝐢𝐧𝐞: iPSCs can differentiate into various tissue types, making them highly adaptable for a range of regenerative treatments. 2. 𝐏𝐫𝐨𝐥𝐢𝐟𝐞𝐫𝐚𝐭𝐢𝐨𝐧 𝐂𝐚𝐩𝐚𝐛𝐢𝐥𝐢𝐭𝐢𝐞𝐬: iPSCs can undergo numerous cell divisions while maintaining their undifferentiated state, allowing for the generation of sufficient cell populations for therapeutic applications. 3. 𝐏𝐞𝐫𝐬𝐨𝐧𝐚𝐥𝐢𝐬𝐞𝐝 𝐌𝐞𝐝𝐢𝐜𝐢𝐧𝐞 𝐏𝐨𝐭𝐞𝐧𝐭𝐢𝐚𝐥: iPSCs are derived by reprogramming somatic cells, resetting their genetic program to produce patient-specific pluripotent cells, which is crucial for personalised medicine. Nice. ➡️ Despite their promise, iPSC therapies face significant challenges, such as mitigating the risk of tumours by removing undifferentiated cells and efficiently guiding iPSCs to differentiate into specific, functional cell types for effective therapies. Not nice. 𝘏𝘰𝘸 𝘥𝘰 𝘺𝘰𝘶 𝘵𝘩𝘪𝘯𝘬 𝘳𝘦𝘴𝘦𝘢𝘳𝘤𝘩𝘦𝘳𝘴 𝘤𝘰𝘶𝘭𝘥 𝘳𝘦𝘥𝘶𝘤𝘦 𝘵𝘶𝘮𝘰𝘶𝘳 𝘳𝘪𝘴𝘬𝘴 𝘪𝘯 𝘪𝘗𝘚𝘊 𝘵𝘩𝘦𝘳𝘢𝘱𝘪𝘦𝘴? 𝐒𝐨𝐮𝐫𝐜𝐞: 𝐋𝐢𝐧𝐝𝐯𝐢𝐥𝐥𝐞 𝐁𝐢𝐨 𝐟𝐨𝐫 𝐭𝐡𝐞 𝐢𝐧𝐟𝐨𝐠𝐫𝐚𝐩𝐡𝐢𝐜 – check out their website. #celltherapy #stemcells #biotech #CGTweekly

🔬Discover the revolutionary 3D perfusion hollow fiber bioreactors from FiberCell Systems Inc. that are transforming cell culture and research. These bioreactors enable in vivo-like cell growth, fostering complex cellular interactions over extended periods. Ideal for co-cultivation, 3D modeling, and parasitology research, they offer unmatched benefits for various applications, including blood-brain barrier models and monoclonal antibody production. 🔍 Explore the full potential of these bioreactors and how they can enhance your research. 👇 Read the full news item via the link in comments #CellCulture #Bioreactors #ResearchInnovation #FiberCellSystems

Why is imaging so important in preclinical research for renal vascular interventions? In this CT scan of arterial and venous renal vascularization in a pig, you’ll see that the renal vein can be bifid. Retrograde catheterization can therefore be very challenging if 100% of the renal blood must be diverted. #preclinical #CTscan #VascularResearch #RenalResearch #MedTech

Gain Therapeutics Presents Preclinical GT-02287 Data at Neuroscience 2024 GT-02287 Demonstrates Disease Modifying Capacity in Both GBA1 and Idiopathic Parkinson’s Disease Models GT-02287 Improves Mitochondrial Function and Provides Neuroprotective Effect in GBA1-Parkinson’s Disease Models GT-02287 Prevents Tau Accumulation in a Cellular Model https://lnkd.in/gNiWjrb9