Remedazo’s Post

If you’ve been placed on the kidney transplant waiting list, or are in the process of being listed, it’s natural to feel confused or overwhelmed by the process. Many patients experience a lack of transparency when it comes to understanding how they’re ranked or how decisions are made. If you pass the evaluation, you’ll be added to the national transplant list, managed by the Organ Procurement and Transplantation Network (OPTN). While UNOS still operates key aspects of the system under a temporary contract, the Health Resources and Services Administration oversees the process as part of the ongoing OPTN Modernization Initiative. The transplant list includes everal factors that determines when and how you might receive a kidney How Do You Get Listed? First off, getting on the kidney transplant waiting list is the result of a detailed medical evaluation at a transplant center. This evaluation assesses your overall health, your ability to undergo surgery, and how well you’ll likely manage post-transplant care. If you pass the evaluation, you’ll be added to the national transplant list, managed by the United Network for Organ Sharing (UNOS). How Are People Prioritized on the List? The following factors will influence your priority: 🥔 Blood type and HLA matching: Your blood type and tissue type need to be compatible with the donor's for a successful transplant. 🥔 Sensitization score (CPRA): If you have developed antibodies due to previous transplants, blood transfusions, or pregnancies, you might have a harder time finding a match. A high CPRA score means you’re "sensitized" and will be given higher priority when a compatible kidney becomes available. 🥔 Waiting time: Time on the waiting list matters, but it’s not the only factor. Patients accrue waiting time from the moment they begin dialysis or are listed as transplant candidates. 🥔 Estimated Post-Transplant Survival (EPTS): This score predicts how long you’re expected to live post-transplant. Younger, healthier patients tend to have higher EPTS scores and may be matched with kidneys that are expected to last longer. 🥔 Kidney Donor Profile Index (KDPI): This score is assigned to donor kidneys based on factors like the donor’s age and health. Lower KDPI kidneys are considered "higher quality" and may be reserved for younger recipients, while higher KDPI kidneys might go to older or sicker patients. 🥔 Geographic proximity: The location of the donor and recipient also matters. it’s crucial to stay informed about your status. Here are a few key questions to ask 🥔 "Can you provide an update on my current status on the kidney transplant waiting list?" 🥔 "How much waiting time have I accrued, and how does that affect my priority?" 🥔 "Have I been considered for any organs recently, and if not, why?" It’s essential to stay in communication with your transplant center and ask specific questions to ensure you’re in the best possible position to receive a transplant

Congratulations!💐💐 Dr Sandeep gangaya Attawar, Vijil Rahulan, Dr.Prabhat Dutta, Dr.Mahesh,Dr.Sonali Arora,Dr.Anoop, Dr.Unmil,Moiz Lalani,Dr. Owais Tisekar, Dr.Manjunath, Dr.Samuel, Dr.Menander,KIMS Hospitals and Team. ##Achieving a new milestone of 500 Thoracic OrganTransplantation and benchmarking International guidlines is remarkebale. Dr Sandeep gangaya Attawar ##MyInspiration## has made significant contributions to the field of Thoracic Organ transplantation particularly in India. His dedication and expertise have played a vital role in leading successful Heart and Lung transplant programs in the Country. Little tought behind the reason to celebrate 500 Thoracic Organ Transplantation and successful transplant program Implementation across the country by Dr Sandeep gangaya Attawar and Team 1.Limited Infrastructure: Developing countries like India lack the necessary infrastructure and facilities required to carry out complex organ transplant procedures. which includes specialized hospitals, transplant centers, and skilled healthcare professionals. The lack of resources and expertise can hinder the availability and success of Heart and lung transplantation. 2.Organ Shortage: A significant challenge of our country, is the limited availability of suitable organs for transplantation. The demand for Heart and lung transplantation exceeds the number of organs available for transplantation, leading to long waiting lists and delays in the process.This problem been amplified due to limited access to organ donation programs and low awareness about the importance of organ donation. 3.Funding and Financial Constraints: The cost associated with transplantation is substantial, including pre-transplant evaluations, surgical procedures, post-operative care, immunosuppressant medications, and long-term follow-up. country is struggling to allocate adequate funding for such high-cost medical procedures due to competing healthcare priorities, limited healthcare budgets, or a lack of health insurance coverage for patients. 4.Lack of Skilled Healthcare Professionals: Thoracic Organ Transplantation is a highly specialized procedure that requires a team of skilled healthcare professionals, including transplant surgeons, Cardiologist, pulmonologists, anesthesiologists, and critical care nurses. our country experience a shortage of such specialists, making it challenging to perform successful transplants. In some places, medical professionals may not have access to updated techniques and training in the field of transplantation. 5.Post-Transplant Care: After a Organ transplant, patients require long-term and comprehensive care to prevent complications, monitor organ function, and manage immunosuppressive therapy. our country face challenges in providing adequate and consistent post-transplant care due to limited resources, infrastructure, and follow-up systems. This can impact the overall success and survival rates of lung transplant recipients.

Understanding the kidney transplant listing process can be complex, and many patients and families often have misconceptions about how it works. Clarifying some key elements, especially regarding kidney transplant recipients who are highly sensitized or have a high Kidney Donor Profile Index (KDPI), is crucial. These factors determine how quickly someone can receive a transplant and why the process may be slower for certain individuals. 📝 Initial Evaluation: The journey starts when a patient with kidney failure is referred for a transplant evaluation. A multidisciplinary team evaluates their health, comorbidities, and surgery suitability. If approved, they are added to the national transplant list. 📋 Listing on the National Registry: Once listed, the patient’s medical information, including blood type, HLA antibodies, and other factors, is entered into the national database to match kidneys based on multiple criteria. The KDPI measures the expected function of a donor kidney. A lower KDPI (0-20%) means a donor kidney will likely function longer, while a higher KDPI (80-100%) suggests a shorter lifespan. Patients with a high KDPI score are offered kidneys from donors with more risk factors (e.g., older age or medical conditions). ⏳ Wait Times: Patients may misunderstand why they are offered certain kidneys. Those accepting a higher KDPI kidney might receive a transplant sooner but must weigh the risks of reduced kidney longevity. ⚖️ Trade-offs: Choosing a high KDPI kidney may reduce the wait but increases the chance of needing another transplant in the future. Some patients are highly sensitized, meaning they have higher levels of HLA antibodies, often due to previous transplants, transfusions, or pregnancies, making it harder to find a compatible donor kidney. 🔬 Highly sensitized patients often wait longer because their body may reject most kidneys. Finding a compatible donor is like finding a "needle in a haystack." 🌍 National listing improves chances for highly sensitized patients by expanding the donor pool but involves logistical challenges like organ transportation and surgery coordination. Why It Takes Longer to Find a Match 🚦 Immune barriers make it harder for highly sensitized patients to find matches, so they are offered fewer kidneys. ⛓️ Careful matching is crucial to avoid rejection, especially for high KDPI or highly sensitized patients, which extends the wait time. 📊 Organs are allocated based on how well the kidney matches the recipient’s immune system, geographic proximity, and wait time. Highly sensitized patients must be matched more carefully, leading to longer waits.

What is the most effective strategy for pre-oxygenation in the critically ill patient pre-intubation? – Michael Christie Pre-oxygenation is a critical step in the management of critically ill patients prior to intubation, aimed at minimizing the risk of hypoxemia during the procedure. The effectiveness of various pre-oxygenation strategies has been the subject of extensive research, highlighting the importance of optimizing oxygen delivery to improve patient outcomes. One of the most widely accepted methods for pre-oxygenation involves the use of a tight-fitting face mask to deliver supplemental oxygen. Studies indicate that while a standard pre-oxygenation period of three minutes is common, extending this duration to eight minutes offers limited additional benefits in terms of preventing desaturation in critically ill patients (Simpson et al., 2012). However, it is crucial to note that the incidence of hypoxemia can be significantly reduced with effective pre-oxygenation techniques (Simpson et al., 2012). In addition to traditional methods, apneic oxygenation has emerged as a valuable adjunct during intubation, particularly in patients who are already hypoxic or in situations where intubation may be prolonged. This technique involves delivering oxygen via nasal cannula during the apneic phase of intubation, which can help maintain oxygen saturation levels and reduce the incidence of hypoxia (Crewdson et al., 2021; , Semler et al., 2016). Research shows that apneic oxygenation can extend the time to serious desaturation, particularly in patients with acute lung injury (Engström et al., 2010). Furthermore, a randomized controlled trial demonstrated that apneic oxygenation significantly decreases the risk of hypoxemia during intubation in critically ill patients (Semler et al., 2016). High-flow nasal cannula (HFNC) therapy is another innovative strategy that has gained traction in the ICU setting. HFNC can provide effective pre-oxygenation by delivering high-flow oxygen, which has been shown to prevent desaturation during intubation attempts, especially in patients with mild to moderate hypoxemia (Miguel-Montanes et al., 2015). The use of non-invasive positive pressure ventilation (NIPPV) has also been advocated, as it can improve oxygen stores and reduce the risk of desaturation during intubation (Divatia et al., 2011; , Myatra et al., 2016). The positioning of the patient during intubation can also influence the effectiveness of pre-oxygenation strategies. Maintaining a semi-recumbent position is recommended to optimize functional residual capacity and minimize the risk of desaturation, particularly in critically ill patients (Frost et al., 2010). https://lnkd.in/grYEE3Xx 👈click here to read more...

🌟 This month we are bringing our #StaffSpotlight to Jacquie Peck, a Clinical Nurse Specialist who does fantastic work with bowel cancer patients and their families. Read more about her role, bowel cancer tests and symptoms below: "I see patients at all stages of their care, so from diagnostic tests, to surgery, chemotherapy and systemic anti-cancer therapies, radiotherapy, through to symptom control and follow-up care, so no two days are the same. It’s a busy but very rewarding job. "There are three main tests for bowel health. The first is a FIT test (Faecal Immunochemical Test). This is a stool test, that checks for microscopic levels of blood that often cannot be seen. In the UK people aged 60-74 are sent this in the post as part of the national bowel cancer screening programme. Bowel cancer is most common in people over the age of 50 so in coming years this screening threshold will be lowered to people over the age of 50. "The second test is a colonoscopy - this is a detailed examination of the whole of the large bowel using a flexible camera. The third is a virtual colonoscopy via a CT scan, this looks at the large bowel and surrounding structures and helps to diagnose the cause of any symptoms. "Both the colonoscopy and virtual colonoscopy looks for signs of bowel disease. The most common of these includes inflammatory bowel disease (Crohns and ulcerative colitis), diverticular disease, irritable bowel syndrome, polyps and cancer. "Bowel screening is the best way to detect cancer at its earliest stage, so I would encourage everyone to take up bowel screening when it is available to them. "Anyone who has the following symptoms should see their doctor for review and further investigation: * Change in bowel habit for more than 3 weeks. This can be constipation or diarrhoea; * Unexplained weight loss; * Waves of abdominal pain; * Iron deficiency anaemia – causing extreme tiredness or fatigue; * A lump in the abdomen; * Bleeding from your back passage, bright or darker red in colour; * Feeling like you haven’t fully emptied your bowels or needing to open your bowels. "I love that I really get to know patients and their families and in many cases I support them for a number of years. Bowel cancer is often highly treatable and it’s really rewarding to see many patients be cured of their disease. In fact, due to advancements in surgery, radiotherapy and medicines over the last 20 years, more and more patients are living for longer, even when cancer has spread to other parts of the body. It’s a very stimulating field and I am excited to see how we can further evolve treatment and improve outcomes in the next 20 years."

In a ground-breaking achievement, successfully performed three consecutive lung transplants in 55hours giving a new lease of life to three terminally ill patients. On the occasion of World Organ Donation Day, celebrated on August 13th, Kauvery Hospital extends heartfelt thanks to the organ donors and their families, our impeccable donor organ coordination authority - TRANSTAN, donor hospitals & our coordinators who make a second lease of life possible for our sick patients with respiratory failure. The success of these transplants highlights the importance of organ donation and the life-saving potential it holds. Lung transplantation is a complex procedure where a diseased lung is replaced with a healthy one from a deceased donor. Despite the challenges, these transplants can significantly improve a patient’s survival and quality of life. Currently, there are two or fewer lung transplants happening within Tamilnadu monthly. The Heart and Lung Transplant team headed by Dr Kumud Dhital at Kauvery Hospital completed three such lung transplants within 55 hours showcasing their expertise and dedication. The first patient is a 72-year old with a BMI of 18 with progressive lung fibrosis on home oxygen and ventilator support underwent a single lung transplant. The second patient, who had lost 40 kgs due to his advanced disease from post-COVID fibrosis, received bilateral lung transplants. An out-of-hours virtual crossmatch was performed to ensure safety of donor-recipient matching for the third patient who was immunologically sensitized, and who received bilateral lungs. The first two patients are already off the ventilator and making excellent progress, while the third patient is also recovering well. All three cases were performed without the traditional peri-operative use of circulatory support. All credit to our amazing surgical team - Dr Kumud Dhital, Dr Prakash Ludhani & Dr Ram for their expertise & to our anaesthetic & critical care team headed by Dr Pradeep. Dr. Srinivas Rajagopala, who with his team of transplant pulmonologists, played a crucial role in the management of these patients with very advanced lung failure, will also be spearheading their long-term surveillance and care after hospital discharge. Credit also goes to our staff in Clinical Perfusion, OR technicians, specialist nurses in the OR and ICU, dedicated physiotherapy, and other multi-disciplinary support staff to make this monumental task possible. The smooth course of recovery of all three patients is a testament to the skill and tireless dedication of the broad transplant team. It also reflects on the delivery of the highest standard of care at Kauvery Hospital whilst underscoring the hospital leadership’s unwavering resolve and commitment to provide such advanced medical care to improve patient outcomes.

In a ground-breaking achievement, successfully performed three consecutive lung transplants in 55hours giving a new lease of life to three terminally ill patients. On the occasion of World Organ Donation Day, celebrated on August 13th, Kauvery Hospital extends heartfelt thanks to the organ donors and their families, our impeccable donor organ coordination authority - TRANSTAN, donor hospitals & our coordinators who make a second lease of life possible for our sick patients with respiratory failure. The success of these transplants highlights the importance of organ donation and the life-saving potential it holds. Lung transplantation is a complex procedure where a diseased lung is replaced with a healthy one from a deceased donor. Despite the challenges, these transplants can significantly improve a patient’s survival and quality of life. Currently, there are two or fewer lung transplants happening within Tamilnadu monthly. The Heart and Lung Transplant team headed by Dr Kumud Dhital at Kauvery Hospital completed three such lung transplants within 55 hours showcasing their expertise and dedication. The first patient is a 72-year old with a BMI of 18 with progressive lung fibrosis on home oxygen and ventilator support underwent a single lung transplant. The second patient, who had lost 40 kgs due to his advanced disease from post-COVID fibrosis, received bilateral lung transplants. An out-of-hours virtual crossmatch was performed to ensure safety of donor-recipient matching for the third patient who was immunologically sensitized, and who received bilateral lungs. The first two patients are already off the ventilator and making excellent progress, while the third patient is also recovering well. All three cases were performed without the traditional peri-operative use of circulatory support. All credit to our amazing surgical team - Dr Kumud Dhital, Dr Prakash Ludhani & Dr Ram for their expertise & to our anaesthetic & critical care team headed by Dr Pradeep. Dr. Srinivas Rajagopala, who with his team of transplant pulmonologists, played a crucial role in the management of these patients with very advanced lung failure, will also be spearheading their long-term surveillance and care after hospital discharge. Credit also goes to our staff in Clinical Perfusion, OR technicians, specialist nurses in the OR and ICU, dedicated physiotherapy, and other multi-disciplinary support staff to make this monumental task possible. The smooth course of recovery of all three patients is a testament to the skill and tireless dedication of the broad transplant team. It also reflects on the delivery of the highest standard of care at Kauvery Hospital whilst underscoring the hospital leadership’s unwavering resolve and commitment to provide such advanced medical care to improve patient outcomes.

DEAR MAYO CLINIC: My friend was just diagnosed with Graves’ disease, but I don’t know much about it. I want to be supportive and educate myself. What is Graves’ disease, and how does it affect the body? How is it treated? ANSWER: Graves’ disease is a condition of the immune system that leads to an overactive thyroid. It is caused by antibodies attacking the thyroid by mistake. The thyroid and the hormones it produces are the gas pedal for the body. When someone produces too much thyroid hormones, the body goes into overdrive. Your pulse increases, you overheat, you lose sleep — these symptoms make people feel so unwell that they seek medical attention. This is what leads to additional testing and the diagnosis of Graves’ disease. In overdrive, muscle strength is lost, and the heart beats faster, adding extra wear and tear. Much like a car running at a high RPM (revolutions per minute) for an extensive period of time, that’s not good for the engine. The goal is to treat this overactive phase when treating Graves’ disease. The main complication of Graves’ disease is thyroid eye disease. Inflammation and bulging of the eyes occur in a third of people diagnosed with Graves’ disease. Managing thyroid eye disease requires an endocrinologist to address the thyroid and ophthalmologists who deal with eye changes. Ear, nose and throat (ENT) specialists are occasionally involved in surgeries related to the eye disease as well. All these specialists operate together in a Thyroid Eye Disease Clinic at Mayo Clinic. The morning is dedicated to the patient moving between the different specialties and performing a set of specific tests. At noon, the specialists meet to discuss patient impressions, review the test results and create a care plan. The patient is seen again in the early afternoon, and the care plan is discussed. This includes suggestions on medication or surgery and clinical trials suited for that patient, dwelling in detail on the route the patient is interested in and contrasting it with the other choices. The benefit of this system is that a patient can get all this analysis done in one day, resulting in increased patient satisfaction. Also, the number of clinical trials is increasing, with more available choices forecasted for patients in the near future. Research and innovation surrounding Graves’ disease is another area of focus for the future. The ability to create molecules that hit a specific target has increased tremendously over the last few years. This is particularly effective when we know the mechanism of a disease and what the target should be. With thyroid eye disease, the main complication of Graves’ disease, we know the receptor we aim to block. There have been a number of clinical trials that we are a part of that aim to block that receptor, improve the eye disease and, for some of these drugs, also treat Graves’ disease at the same time. Targeting some of these areas has resulted in noticeable

🅰️🅱️🆎🅾️ Unlocking the Mysteries of Blood Group Testing: Clinical Insights💉🔍 Let's explore the clinical significance of the blood group test and its pivotal role in patient care. Understanding Blood Group Testing: The blood group test, also known as blood typing, is a laboratory procedure designed to determine an individual's blood group based on the presence or absence of specific antigens and antibodies on the surface of red blood cells. The most common blood group systems include the ABO system and the Rh system, which classify blood into distinct groups: A, B, AB, O, and Rh-positive or Rh-negative. Clinical Significance: 1. Blood Transfusion Compatibility: Blood group testing is paramount in ensuring compatibility between donor and recipient blood during transfusion procedures. Matching the blood types of the donor and recipient minimizes the risk of adverse reactions, such as hemolytic transfusion reactions, and promotes safe and effective transfusion practices. 2. Pregnancy Management: Blood group testing plays a crucial role in managing pregnancies, particularly in Rh-negative women. Rh compatibility between the mother and fetus is assessed to prevent Rh isoimmunization, a condition where maternal antibodies attack fetal red blood cells, leading to hemolytic disease of the newborn. 3. Organ and Tissue Transplantation: Matching blood groups between organ donors and recipients is essential in organ and tissue transplantation to reduce the likelihood of rejection and improve graft survival rates. Blood group compatibility is assessed to minimize the risk of immune-mediated complications post-transplantation. Patient Impact: 1. Safe Transfusion Practices: Accurate blood group determination facilitates safe and compatible blood transfusions, reducing the risk of transfusion-related complications and promoting positive patient outcomes. 2. Preventative Care: Knowledge of blood type enables healthcare providers to implement preventative measures, such as Rh immunoprophylaxis in Rh-negative pregnant women, to mitigate the risk of hemolytic disease of the newborn and other Rh-related complications. 3. Optimized Treatment Strategies: Blood group information guides treatment decisions in various clinical scenarios, such as emergency situations, surgical procedures, and trauma care, ensuring tailored and effective therapeutic interventions. The blood group test serves as a cornerstone in transfusion medicine, obstetrics, and transplantology, offering invaluable insights into blood compatibility and patient management. ⚕️I’m Dennis Odoi empowering you to seize control of your health. ⚕️Follow along to join a community of like-minded commanders. ♻️ Repost to save a life #BloodGroupTesting #TransfusionMedicine #PatientCareExcellence Day 123/366 Days

Update 1 on my brother's medical condition - His myositis has worsened, leading to lung fibrosis. My brother needs a lung transplant as early as possible. He is still on ECMO. I am sharing the urgent plea written below with my connections. It is a request to all my connections to help and contribute in any possible way you can. You can also contact me at +918328996455 for any further information. Dear all, I am Itu Dutta, a resident of Rourkela, Odisha, India. I am reaching out to you with a heavy heart and a sense of urgency regarding a critical matter that needs immediate attention. My son, Mr. Debojeet Dutta, age 17, is battling a severe lung injury resulting from myositis, a rare autoimmune disease affecting muscles and lungs. Currently, he's undergoing treatment with ECMO to sustain his life. Debojeet has been battling undetected infections since February 22nd, 2024. Initially treated at HiTech Hospital, Rourkela, and later at Apollo Hospital, Bhubaneshwar, the infection persisted undetected. His condition worsened, and on March 26th, he was transferred to Naruvi Hospital Vellore. At Naruvi Hospital, proper investigations, including CT scans and tests, revealed a rare form of myositis, which has severely affected his lungs, progressing to acute respiratory failure. He has been in the Coronary Care Unit under an external artificial life support machine since March 29th and still requires ECMO support. He has been treated with immunosuppressive drugs, but the treatment has led to no improvement as fluids have started to fill his damaged lungs. Due to the prolonged damage to his lungs, his lungs have started showing signs of fibrosis. As a result, the doctors have declared that he will require a lung transplant as early as possible. The doctors have provided an unofficial estimated cost of INR 20 lakhs for the transplantation.  Despite our best efforts, our family is struggling to meet the exorbitant costs associated with Debojeet's treatment, including medical bills, equipment fees, and other related expenses. In this crisis, I appeal to your generosity and compassion to consider extending financial assistance to alleviate the burden on our family.Anup Kumar Dutta: (Father) A/C no. 10143983957 IFSC code: SBIN0005762 Contact number: +919938271647 Itu Dutta: :(Mother) UPI ID: itudutta174@okicici Contact number: +917978581167 You can also contribute to Milaap-  https://lnkd.in/gM5iUcqV I would appreciate your every share and contribution. You can also pay on my UPI ID, ephimeralsam8@oksbi