Learn how scientists are using varying techniques and technologies to further their multiple sclerosis drug discovery research with this literature review. http://ms.spr.ly/6041YuP8t #lifesciences #drugdiscovery
Revvity for Life Sciences’ Post
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The Echo® MS+ system can combine sample preparation, analysis, and reporting to overcome high-throughput challenges in drug discovery. Reliable mass spectrometric data can be collected at up to 1 sample per second. Curious to know more about what is possible and how it is possible? Learn more here 👉 https://bit.ly/4cfUXUo #EchoMS+ #AEMS #PharmaDiscovery #HTS
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Biostatistician | Data Analyst| Statistical Consultant | Health Care Research | Clinical Research | Analyzing projects | Meta-Analysis | Data Entry expert| More than 50 Published Articles
We're delighted to share a summary of our mini review article in Frontiers in Drug Discovery journal with IF 3.1. In this article we reviewed the anticancer properties of Cryptotanshinone. For more detailed results please read the full text: https://lnkd.in/d_5_KHzX
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Researchers at the University of Toronto have developed a #DeepLearning model, called PepFlow, that can predict all possible shapes of peptides. PepFlow can inform drug development through the design of peptides that act as binders. #DrugDiscovery Learn more 👉 https://uoft.me/PepFlow
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DNA-encoded library (DEL) technology accelerates drug discovery by using vast libraries of tiny molecules, each tagged with DNA for rapid identification and sorting. Enhanced with dynamic libraries, a path-coding algorithm, binding profiler validation, and MicroMapping for precise spatial analysis, this approach streamlines the search for new medicines. Learn more in this on-demand webinar.
Revolutionizing Drug Discovery: DEL and Micromapping Technology
event.on24.com
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Missed SLAS earlier this month? Make sure to download our poster! From the 3rd to 7th February, we were in Boston for the Society for Laboratory Automation and Screening (SLAS) International Conference, discussing our work with human iPSC technology for research and drug discovery. Alongside discussions on quality iPSC manufacturing, functional QC and in vitro models, we presented a poster titled "Differentiation of multiple iPSC lines to different cell types to enable cohort analysis in neurodegeneration: challenges and learnings". Listen to our Project Manager, Sian Humphreys presenting the key findings in the poster: https://hubs.la/Q02m2bc70 Click here to download the poster: https://hubs.la/Q02m24Zy0 #iPSCs #SLAS #biotech #StemCells #DrugDiscovery
Axol Bioscience - Poster Presentation at SLAS 2024
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Assay technologies and methodologies have been developed to identify chemicals that can be used for drug discovery. Miniaturized assays and encoded libraries help to increase the speed and efficiency of this process. To create more accurate formats, complex cell models of disease states are being utilized. This review article focuses on recent developments in high-throughput assay technologies that are used to identify starting points for drug discovery. Furthermore, it will provide recommendations for selecting high-quality leads that can be used for drug development. #AssayTechnologies #DrugDiscovery #HighThroughputAssays #EncodedLibraries #CellModels #DrugDevelopment #ScienceAndTechnology #ResearchAndDevelopment
Advancements in Assay Technologies and Strategies to Enable Drug Discovery
pubs.acs.org
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"Make or break questions for a drug discovery project often come down to, “does modulating this target do what we want?” and, “what else does modulating this target do?” In order to answer those questions quickly and make drug discovery decisions with confidence, an understanding of target engagement and corresponding on- and off-target effects on biology is critical. " https://lnkd.in/g3W2gTN5 #drugdiscovery #drugdelivery #decisiontools
Minimum Viable Experiments with Imperfect Molecules: a Minipump Minireview
drughunter.com
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Unlock the potential of bioanalytics with advanced technologies and techniques. Discover how to develop and validate methods that meet regulatory requirements, and how to tackle the most complex challenges. Access our curated series of technical content to make the most of your research. Achieve unprecedented levels of sensitivity—learn how 👇 https://bit.ly/3N6GwbD #Bioanalysis #SCIEX #DrugDiscovery
New Frontiers in Bioanalysis
sciex.com
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Let’s enable drug discovery together by embracing new possibilities in target acquisition and innovation, streamlining research processes, and achieving reliable, consistent results. And more is yet to come. What are you waiting for?
𝗨𝗻𝗹𝗼𝗰𝗸𝗶𝗻𝗴 𝗠𝗲𝗺𝗯𝗿𝗮𝗻𝗲 𝗣𝗿𝗼𝘁𝗲𝗶𝗻𝘀 𝘄𝗶𝘁𝗵 𝘁𝗵𝗲 𝗡𝗮𝘁𝗶𝘃𝗲𝗠𝗣™ 𝗧𝗮𝗿𝗴𝗲𝘁𝘀 Working with complex membrane proteins, like GPCRs and ion channels, is a major challenge in drug discovery. These targets are vital for many biological processes yet notoriously difficult to handle, especially when 𝗹𝗶𝗽𝗶𝗱 𝗶𝗻𝘁𝗲𝗿𝗮𝗰𝘁𝗶𝗼𝗻𝘀 and 𝗽𝗵𝘆𝘀𝗶𝗼𝗹𝗼𝗴𝗶𝗰𝗮𝗹 𝘁𝗲𝗺𝗽𝗲𝗿𝗮𝘁𝘂𝗿𝗲𝘀 add layers of complexity. This Summer, the NativeMP™ Targets have changed the game by maintaining membrane proteins in their native environment—enabling high-quality assays, deep insights into 𝗽𝗿𝗼𝘁𝗲𝗶𝗻-𝗹𝗶𝗽𝗶𝗱 𝗶𝗻𝘁𝗲𝗿𝗮𝗰𝘁𝗶𝗼𝗻𝘀, and application versatility at physiological conditions. We were already able to present data from a wide array of protein classes, acquired detergent-free, rapidly solubilized, and stabilized directly from the cell. Even large and complex targets, such as 𝗧𝗟𝗥𝟱, 𝗔𝗕𝗖𝗔𝟭𝟮, or coexpression of 𝗜𝗧𝗚𝗕𝟯/𝗔𝗩 have been possible. And more is yet to come. What are you waiting for? 👉 Let’s enable drug discovery together by embracing new possibilities in target acquisition and innovation, streamlining research processes, and achieving reliable, consistent results. #drugdiscovery #membraneproteins #nativeMP
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Choosing the right cells for drug testing can make all the difference in understanding how your drug interacts with a living system. But with so many cell types out there, you still do not find the tissue you need? Fret not! Contact Kosheeka at +919654321400 to take advantage of custom tissue culture to accelerate your research. #cellculture #primarycells #research #drugtesting #kosheeka
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