RIFFATH UZ ZAMAN Rounik’s Post

Blockade of the orexin receptors in the ventral tegmental area could attenuate the stress-induced analgesia: A behavioral and molecular study https://lnkd.in/e9H2GxDx

Implications of Complement Imbalance in COVID-19: A Molecular Mechanistic Discussion on the Importance of Complement Balance https://lnkd.in/erHPjcwz

A new paper on the hot topic of identification/generation of covalent monovalent degraders. From the abstract... Our results show that chemoproteomic approaches can be used to covalently target and degrade challenging transcription factors like CTNNB1 through destabilization-mediated degradation.

If you missed Xiaojing Huang’s webinar on molecular glues, you can now watch it on-demand! This webinar explains how #MassPhotometry can be used to explore how molecular glues mediate complex formation between E3 ligases and their targets. Watch it here! 👉 https://lnkd.in/dVefiyPY

New 3i Investigator Article Alert!! β-Hydroxybutyrate and melatonin suppress maladaptive UPR, excessive autophagy and pyroptosis in Aβ 1-42 and LPS-Induced SH-SY5Y cells https://lnkd.in/gFHGiN7U

Different experimental groups, same western blot bands. These two gels are presented as separate figures in the same article. Should this be a correction or a retraction? Please put your answers in the comments below.

favorale evolution of a SIF (subchondral insufficiency fracture). Case discusion ENG. Thanks for watching, following or sharing. Link in the first comment

I am happy to share our recent publication entitled "Crosstalk of Biostimulants with other Signaling Molecules under Abiotic Stress"

Learn how to use GEMME on disordered proteins: https://lnkd.in/e4qujBdE

Breathtaking preprint by the group of Kai (Jack) Zhang that directly images intact extracted mitochondria using in situ cryo-EM, determining the atomic structures of mitochondrial respiratory supercomplexes in the native membrane enrironment at up to 1.8 Å resolution. https://lnkd.in/gu_jtzKq