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View profile for Dominic Brittain, graphic

Experienced R&D leader at Novartis

Pleased to be able to share the topline results from our latest Phase III study, the first to show the effects of an siRNA therapy as a monotherapy in lowering cholesterol levels in patients at low or moderate risk of atherosclerotic cardiovascular disease. Thanks to all the V-MONO patients, investigators, site staff and Novartis scientists for making this possible.

Novartis twice-yearly* Leqvio® demonstrated clinically meaningful, statistically significant LDL-C lowering as a monotherapy in patients at low or moderate ASCVD risk

Novartis twice-yearly* Leqvio® demonstrated clinically meaningful, statistically significant LDL-C lowering as a monotherapy in patients at low or moderate ASCVD risk

novartis.com

David Soergel MD

Global Head Drug Dev, CVM at Novartis

2w

Congrats Dominic and team!

Vasilisa Sazonov, PhD

International Therapy Area Head Cardiovascular-Renal-Metabolic

2w

Well done team Leqvio! And thank you.

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Congrats Dominic! I hope you are well.

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Donald Banerji

Physician Scientist -Global Drug Development

2w

Outstanding results! Congratulations Dominic and Team!

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