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Thank you to all for this collaborative work. All my thanks to Arrigo Fruscalzo Ioannis Dedes Michael D. Mueller Carolin Marti Benedetta Guani @Adamantios Athanasiou Adenomyosis is a debilitating gynecologic condition that affects both multiparous older women and nulliparous younger women, inducing a variety of symptoms such as dysmenorrhea, menorrhagia, and infertility. Thermal ablation techniques are new procedures that have been proposed for the treatment of adenomyosis. They include high-intensity focused ultrasound (HIFU), percutaneous microwave ablation (PMWA), and radiofrequency ablation (RFA). Because thermal ablation techniques are minimally invasive or noninvasive, fertility is not impaired while symptoms improve. In addition, hospital stays and financial costs are generally reduced, increasing the interest in these alternative management options. Methods: In this narrative review, we conducted a thorough literature search of PubMed/Medline from the database inception to September 2022. In our search, we focused on noninvasive treatment methods such as HIFU ablation, RFA ablation, and PMWA as well as adenomyosis-specific terms and noninvasive techniques (ultrasonography, ultrasound, or magnetic resonance imaging). The queries were a combination of MeSH terms and keywords. The search was limited to the English language. Abstracts were screened according to their content, and relevant articles were selected. Results: Overall, the results showed that the above-mentioned ablation techniques are effective and safe in providing adenomyosis treatment. Lesion size and uterus volume are reduced, leading to considerable symptom alleviation with all three methods. Positive results concerning safety and fertility preservation have been described as well. Conclusions: Nonetheless, more research is required in this field to compare the efficacy and safety of different ablation techniques with traditional therapies. Such research will help improve these procedures and their associated decision-making processes. https://lnkd.in/exqhZ6jX

Hello Everyone, Today, I want to share a few thoughts on a principle that has not only guided me through my journey with Skinaa Clinic but has also been a cornerstone of my personal and professional life: "Trust your hard work, it is unlocking a new path for you." In our lives, we often encounter obstacles that seem insurmountable. During such times, doubt and fear can easily cloud our judgment. It's in these moments, however, that trusting in the hard work we've put in becomes crucial. It's not just about the effort you expend but also about believing that this effort will bear fruit, even if the results are not immediately visible. At Skinaa Clinic, when we started, the path was not clear, and the challenges were daunting. The world of dermatology is both complex and competitive. Each day presented new challenges, from understanding patient needs to delivering innovative treatments. But it was our commitment to hard work and continuous improvement that set us on a path of growth and success. Remember, every bit of hard work is like planting a seed. At first, it seems like nothing is happening, but underground, everything is changing. You are setting roots, building a foundation so strong that when the results finally sprout, they are robust and fruitful. Trust in this process. Believe in your hard work, for it is indeed paving a new path—a path that could lead you to places beyond your current aspirations. I encourage each of you to persevere, to remain diligent and focused. Embrace the challenges, for they teach you lessons that success alone could not. Let your hard work be your guide, let it open new doors and shine a light on opportunities that were once hidden in the dark. As we continue on our respective journeys, let us not grow weary of doing good, for at the proper time we will reap a harvest if we do not give up. Trust your hard work, trust the process, and watch as it unlocks incredible new paths for you. Thank you. Dr. Atul Jain Skinaa

Pure hard work from the team. Kudos to Karthik Chintharala Niharika Reddy. Thank you everyone. This is an interesting review paper which highlights the important role of gut microbiota in affecting brain function, and its possible effects on neurological disorders. The gut-brain axis can either make brain problems worse or better. Hence, this paper concludes that an imbalance in the gut's microbiota can cause brain inflammation, chemical imbalances, and microglial and mitochondrial impairment— all of which are common features in various neurological disorders. This suggests that the gut-brain axis, through infections, metabolites, immune communication, and microglial and mitochondrial dysbiosis, impacts neurophysiological function and cognition. Understanding these complicated connections helps find new ways of treatment approaches aimed at improving neurological health outcomes for people suffering from neurological diseases. https://lnkd.in/gZsA-cry

Although the human body is an incredibly complex biological system composed of trillions of cells, it is subject to the same fundamental laws of mechanics that govern simple metal or plastic structures. The study of the response of biological systems to mechanical forces is referred to as Biomechanics. Biomechanics is often referred to as the link between structure and function. Although it wasn’t recognized as a formal discipline until the 20th century, biomechanics has been studied by the likes of Leonardo da Vinci, Galileo Galilei, and Aristotle. The application of biomechanics to the musculoskeletal system has led to a better understanding of both joint function and dysfunction, resulting in design improvements in devices such as joint arthroplasty systems and orthotic devices. Basic musculoskeletal biomechanics concepts are important for clinicians eg physical and occupational therapists and orthopaedic surgeons. A therapist assessment of a patient typically includes a biomechanical analysis. Biomechanics is an interdisciplinary field that applies the principles of physics to biological systems to understand how organism move and interact with their surroundings. Biomechanics is concerned with everything from microscopic systems like muscle contraction in cells, all the way to large-scale, whole-body motions like a sprinting athlete . Biomechanics applies the laws of physics with regards to levers, pulleys and other known functions to define and understand the complicated forces involved in biological systems. Thank you to our team Dr S. ATHEENA MILAGI PANDIAN sir, Rashika Murugan Varma V sir MOHAMMED SAHIL S Sudherson M Kriya Sakthi M Aruna V Dhanushya S Krithina Dharmarajan Thanks and Best Regards Biomedourse ATHEENAPANDIAN Subsidiary of ATHEENAPANDIAN - India's No.1 Biomedical Industry for Training & Placements PH. +918807039891 WWW.ATHEENAPANDIAN.COM

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Thank you so much for all your lovely messages yesterday ❤️ I'm going to give some background on him and what happened. As well as dolated cardiomyopathy he has something called coarctation of the aorta...dead tissue in his aorta that doesn't grow so its like water trying to get through a squeezed hosepipe...it cant...so pressure builds up and reduced flow through. Age 3 he was one of the youngest in the country (only Bristol offered it) and part of a study offering younger children a Stent as an alternative to open heart surgery. As it wasn't previously offered there was no proof of the benefits as seen in other countries such as Saudi. It's not without risk but any surgery has risks but reduces recovery time and no scar tissue in the aorta, meaning extra surgery at some point. Last year the research paper was published, of which Oliver was part of (and will continue to be) and now it's being g slowly offered elsewhere. Well.....he was all prepped and all the risks explained and options. His aorta has dead tissue which has meant that as he grows it narrows, meaning the blood can't get through meaning his blood pressure is raised and initially when it was discovered age 3, the aorta should be 10mm fully open but his was at 2mm at the problem area and had they waited he would have had a stroke/died. He's had it widened once and they initially thought it'd be dilated as and when necessary until he is 16-18. As they've researched they've seen that the stents can fracture once at full capacity (like a balloon) so he was thinking that an adult Stent would be possible though risky as the artery has to be big enough to take it and risk of losing his leg. The echo he had showed reduced blood flow. ⏩to the op....blood flow actually ok and Stent still functioning (echocardiogram doesnt always paint a true picture) Sought second opinion and agreed that there was no need to do anything.. He would have physically been able to have the new Stent but not justifiable for the potential risks involved as it wasn't necessary. He will have it placed in a few years but as the echo doesnt tell the truth fully, they will go by his blood pressure and when its bad enough to need an extra set of blood pressure meds instead. He's staying in and feels like 💩 as they still had to go in through his groin so has a fair wound but oddly pleased he didn't need anything doing as there's less risk the older he is. He's now ordering me around like im his personal butler! Life's been a rollercoaster for 11 years (he was in exactly 11 years ago and we were faced with an uncertain future)but life has a funny way of teaching us lessons and helping us learn and grow. We give thanks to his amazing surgeon Demetris Taliotis and the many like him for saving Oliver's life and all the other heart warriors out there. Excuse the essay but hard to explain briefly! #positivity #heartwarrior #NHS

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Got a minute for a funny thought? What if surgeons could play with dogs, use cool video game gloves, and solve puzzles in a make-believe world? Here’s how these fun ideas could make a surgeon’s day awesome: 💡Pet Therapy Breaks Imagine stepping out of a tense surgery to be greeted by a wagging tail or a purring friend. Hospitals and clinics introducing pet therapy areas can offer surgeons a much-needed mental reset. These brief, joyful interactions have been shown to reduce stress and increase feelings of happiness. Plus, who can resist those furry faces? 💡Haptic Feedback Gloves Enter the world of sci-fi with haptic feedback gloves designed for surgeons. These gloves could simulate the feeling of tissues and organs, offering a unique way to practice complex procedures without the need for actual patients or cadavers. It’s a blend of video gaming and serious medical training, adding an element of fun to the relentless pursuit of perfection. 💡 Virtual Reality (VR) Escape Rooms After a day of making critical decisions, why not unwind with decisions of a different kind? VR escape rooms for surgeons could blend relaxation with critical thinking, offering a fun, immersive way to decompress while solving puzzles in fantastical settings. It’s a way to keep the brain engaged, but in a completely different world, far away from the pressures of the hospital. _____________ If you liked this, why not sign up for my newsletter? 📨 You’ll be joining a warm community of over 900+ folks where I share tips and bits to help you get on in your medical career and keep a good balance in life. Looking forward to having you with us! 👉 https://ehabbadran.ck.page

Hi, Help Save Our dear Friend and colleague Pradeep: Urgent Support Needed Following a Devastating Accident Day before, our friend and colleague Pradeep a dedicated service engineer working in Bangalore, faced a horrific road accident when his motorcycle collided head-on with a car. Now in critical condition, he urgently needs a craniotomy to survive, but the cost of this life-saving surgery is a staggering ₹700,000/- a sum that is far beyond his financial reach. *The cost of his treatment amounts to Rs. 7,00,000. Unfortunately, this is a significant financial burden for us, and we are unable to cover the expenses on our own.* *Donation Link* : https://lnkd.in/ghtAEbrc - Bank Name: RBL Bank - Account number : 2223330054733417 - Account name : Pradeep B - IFSC code : RATN0VAAPIS (The digit after N is Zero) For UPI Transaction: supportpradeep652@yesbankltd