Samahitha Research Solutions’ Post

In case you haven’t seen: There is an ongoing consultation on an improved guidance on non-inferiority trials:

Is It Truly Pneumonia? Concentrate on Raises questions about Medical clinic #Truly #penumonia #raises #medical #clicic Go Link : https://lnkd.in/gFqVnU6u

Need CME credit? Review management strategies of several clozapine-related adverse effects and outline considerations when addressing inadequate positive symptom response to clozapine in our latest CME article! https://lnkd.in/eifPvAZM

ConcePTION’s goal is to give women the opportunity to take informed decisions about their health and treatment also during the vulnerable periods of pregnancy and breastfeeding. This is hard, because these women are often excluded from clinical trials to protect their babies. And to be able to offer sound advice, a lot of data is needed. To be able to explore the safety of medicines during breastfeeding at a scale that provides enough data to fill the knowledge gap, animal models and in vitro studies are necessary. A recent publication outlines why isolated epithelial cells from Göttingen Minipigs are a good fit to create an in vitro model to study the blood milk barrier. Read about the paper: https://lnkd.in/dTDBbrNQ Read the paper: https://lnkd.in/d6jRT9Fy Chiara Bernardini, Salvatore Nesci, Debora La Mantia, Roberta Salaroli, Nina Nauwelaerts, Domenico Ventrella, Alberto Elmi, Fabiana Trombetti, Augusta Zannoni & Monica Forni Innovative Health Initiative (IHI)

How can #DrugUtilisation studies help to close knowledge gaps about #MedicationSafety in pregnancy? 🤔Learn more in this recent IMI ConcePTION publication. How BBMRI-ERIC is contributing to the Conception project 👉https://lnkd.in/dw_NnUnD 

Drug utilisation studies are used to explore the medical, social and economic effects of the marketing, distribution, prescription and use of a medicine in society. Unlike clinical trials, these studies are performed after a treatment has already been brought to market. In the case of medicine safety in pregnancy and breastfeeding, drug utilisation studies play an important role in filling the knowledge gap, providing a firm foundation for safety studies by contextualising spontaneous reporting of serious adverse events. In a paper recently published in Journal of Pregnancy, the authors outline how these studies should be designed to be useful for this purpose. Read about the paper: https://lnkd.in/d5Hb-KY8 Read the paper: https://lnkd.in/dNrbzE_K Sandra Lopez Leon, Anja Geldhof, Julie Scotto, Keele Wurst, Meritxell Sabidó, Jinping Mo, Ditte Mølgaard-Nielsen, Jorieke van Kamme-Bergman, Xuan Ahn Phi & Sue Jordan Innovative Health Initiative (IHI) #IMICarrytheTorch

Firm Step - Defining Step

JUST PUBLISHED | Traditionally, studies on medicine safety during pregnancy and around the time of conception focus on the mothers. There is a need to explore the safety of paternal drug exposure and its potential effects on pregnancies. A recent publication from the ConcePTION project in Pharmacoepidemiology and Drug Safety outlines the knowledge gaps. Read the paper https://lnkd.in/dP4gyrS4 Read about the paper https://lnkd.in/dFCuJVWN Sneha Gaitonde, Yola Moride, Elizabeth Suarez, Sandra Lopez Leon Innovative Health Initiative (IHI)

🤰 We are learning more and more about #MedicineSafety for women during #pregnancy and near the time of #conception. But how does the #MedicationUse and #DrugExposure of fathers affect pregnancies? This new IMI ConcePTION project publication in the Wiley journal "Pharmacoepidemiology and Drug Safety" outlines what we do (and do not) know. 👉 https://lnkd.in/dP4gyrS4

How to Get Semaglutide: The Ultimate Guide to Affordable Access